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Co-existent ulcerative colitis and Guillain–Barré syndrome: a case report and literature review

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Abstract

Ulcerative colitis (UC) is a chronic and recurrent inflammatory disease involving the intestine, and Guillain–Barré Syndrome (GBS) is rapid-onset muscle weakness caused by the immune system damaging the peripheral nervous system. UC and GBS can be caused by immune system abnormalities and can co-exist. To date, there are 7 reported cases of GBS in patients with UC. However, only one patient developed UC after GBS treatment. We report a rare case of UC that appeared after intravenous immunoglobulin therapy for GBS. This case report and literature review will allow accurate and prompt diagnosis of co-existent GBS and UC.

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Authors and Affiliations

  1. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757, Aasahimachi-Dori, Chuo-Ku, Niigata, Niigata, 9518510, Japan

    Kentaro Tominaga, Atsunori Tsuchiya, Hiroki Sato, Atsushi Kimura, Chiyumi Oda, Kazunori Hosaka, Yuzo Kawata, Naruhiro Kimura, Kazunao Hayashi, Junji Yokoyama & Shuji Terai

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  1. Kentaro Tominaga
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  2. Atsunori Tsuchiya
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  3. Hiroki Sato
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  4. Atsushi Kimura
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  5. Chiyumi Oda
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  6. Kazunori Hosaka
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  7. Yuzo Kawata
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  8. Naruhiro Kimura
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  10. Junji Yokoyama
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  11. Shuji Terai
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Corresponding author

Correspondence to Atsunori Tsuchiya.

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Conflict of interest

Kentaro Tominaga, Atsunori Tsuchiya, Hiroki Sato, Atsushi Kimura, Chiyumi Oda, Kazunori Hosaka, Yuzo Kawata, Naruhiro Kimura, Kazunao Hayashi, Junji Yokoyama and Shuji Terai declare that they have no conflict of interest. The authors declare that they have no current financial arrangement or affiliation with any organization that may have a direct influence on their work.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from all patients for being included in the study.

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Tominaga, K., Tsuchiya, A., Sato, H. et al. Co-existent ulcerative colitis and Guillain–Barré syndrome: a case report and literature review. Clin J Gastroenterol 12, 243–246 (2019). https://doi.org/10.1007/s12328-019-00939-1

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  • DOI: https://doi.org/10.1007/s12328-019-00939-1

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