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Update on Bowel Preparation for Colonoscopy

  • Colon (JC Anderson, Section Editor)
  • Published:
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Abstract

Purpose of review

Colonoscopy is the gold standard for visualization and diagnosis of conditions involving the colon and terminal ileum. It also facilitates screening and prevention of colorectal cancer, which is the second leading cause of cancer death in the USA. Adequate cleansing is essential for thorough visualization of the colon with successful detection of colon polyps.

Recent findings

While the original large-volume polyethylene glycol preparations are still commonly used, several lower volume regimens are widely available and selected based on provider and patient preferences. There remains a strong urge from patients for an even lower volume and more palatable regimen. Split-dose preparation is strongly recommended and additional data has come to support same-day preparation regimens as well. Despite extensive research and comparison of various preparation regimens, between 10 and 25% of patients continue to have inadequate colon cleansing on the day of colonoscopy. Several patient factors have been associated with poor preparation and this chapter will touch on scoring systems, which may be used to predict colon cleansing. Documentation of preparation quality is essential to guide the practitioner in timing of follow-up examination. We recommend the use of the Boston Bowel Preparation Scale (BBPS) which is a validated and reliable scale for evaluation of cleansing. In patients with an inadequate preparation, we emphasize the importance of repeat examinations with consideration of a more aggressive preparation regimen. We predict that dietary liberalization prior to colonoscopy will be more commonly practiced in the future as it improves both patient satisfaction and adherence.

Summary

Thorough bowel cleansing is essential for visualization of the colon with successful detection of colon polyps. While polyethylene glycol regimens are still the most commonly used for preparation, recommendations regarding dose timing and volume continue to evolve to optimize patient satisfaction and success of bowel cleanse. As the patients presenting for colonoscopy are evermore complex with medical comorbidities and extensive medication lists, a patient-centered approach to colonoscopy preparation will likely yield the highest rates of success.

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References and Recommended Reading

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  1. Baxter NN, Goldwasser MA, Paszat LF, Saskin R, Urbach DR, Rabeneck L. Association of colonoscopy and death from colorectal cancer. Ann Intern Med. 2009;150(1):1–8. https://doi.org/10.7326/0003-4819-150-1-200901060-00306.

    Article  PubMed  Google Scholar 

  2. •• Brenner H, Chang-Claude J, Jansen L, Knebel P, Stock C, Hoffmeister M. Reduced risk of colorectal cancer up to 10 years after screening, surveillance, or diagnostic colonoscopy. Gastroenterology 2014;146(3):709–717. https://doi.org/10.1053/j.gastro.2013.09.001. This landmark study provides support for colonoscopy as a screening tool to prevent development of colorectal cancer.

  3. Clark BT, Rustagi T, Laine L. What level of bowel prep quality requires early repeat colonoscopy: systematic review and meta-analysis of the impact of preparation quality on adenoma detection rate. Am J Gastroenterol. 2014;109(11):1714–23; quiz 1724. https://doi.org/10.1038/ajg.2014.232.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Jang JY, Chun HJ. Bowel preparations as quality indicators for colonoscopy. World J Gastroenterol. 2014;20(11):2746–50. https://doi.org/10.3748/wjg.v20.i11.2746.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Froehlich F, Wietlisbach V, Gonvers JJ, Burnand B, Vader JP. Impact of colonic cleansing on quality and diagnostic yield of colonoscopy: the European Panel of Appropriateness of Gastrointestinal Endoscopy European multicenter study. Gastrointest Endosc. 2005;61(3):378–84. https://doi.org/10.1016/S0016-5107(04)02776-2.

    Article  PubMed  Google Scholar 

  6. Harewood GC, Sharma VK, de Garmo P. Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia. Gastrointest Endosc. 2003;58(1):76–9. https://doi.org/10.1067/mge.2003.294.

    Article  PubMed  Google Scholar 

  7. • ASGE Standards of Practice Committee, Saltzman JR, Cash BD, Pasha SF, Early DS, Muthusamy VR, et al. Bowel preparation before colonoscopy. Gastrointest Endosc 2015 ;81(4):781–794. This is the most recent guideline on bowel preparation from the American Society of Gastrointestinal Endoscopy.

  8. Radaelli F, Paggi S, Repici A, Gullotti G, Cesaro P, Rotondano G, et al. Barriers against split-dose bowel preparation for colonoscopy. Gut. 2017;66(8):1428–33. https://doi.org/10.1136/gutjnl-2015-311049.

    Article  CAS  PubMed  Google Scholar 

  9. Menees SB, Kim HM, Wren P, Zikmund-Fisher BJ, Elta GH, Foster S, Korsnes S, Graustein B, Schoenfeld P Patient compliance and suboptimal bowel preparation with split-dose bowel regimen in average-risk screening colonoscopy. Gastrointest Endosc 2014;79(5):811–820.e3, https://doi.org/10.1016/j.gie.2014.01.024.

  10. Hassan C, Fuccio L, Bruno M, Pagano N, Spada C, Carrara S, et al. A predictive model identifies patients most likely to have inadequate bowel preparation for colonoscopy. Clin Gastroenterol Hepatol. 2012;10(5):501–6. https://doi.org/10.1016/j.cgh.2011.12.037.

    Article  PubMed  Google Scholar 

  11. Dik VK, Moons LM, Huyuk M, van der Schaar P, de Vos Tot Nederveen Cappel WH, PC TB, et al. Predicting inadequate bowel preparation for colonoscopy in participants receiving split-dose bowel preparation: development and validation of a prediction score. Gastrointest Endosc. 2015;81(3):665–72. https://doi.org/10.1016/j.gie.2014.09.066.

    Article  PubMed  Google Scholar 

  12. Johnston ER, Keswani RN, Cyrus R, Werth L, Grande D, Yadlapati R. The Nursing Bowel Preparation Assessment Tool (NBPAT) is highly predictive of inpatient bowel preparation adequacy: a prospective pilot study. Gastrointest Endosc. 2015;81(5):AB154.

  13. Hassan C, Bretthauer M, Kaminski MF, Polkowski M, Rembacken B, Saunders B, et al. Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy. 2013;45(2):142–50. https://doi.org/10.1055/s-0032-1326186.

    Article  CAS  PubMed  Google Scholar 

  14. DiPalma JA, Marshall JB. Comparison of a new sulfate-free polyethylene glycol electrolyte lavage solution versus a standard solution for colonoscopy cleansing. Gastrointest Endosc. 1990;36(3):285–9. https://doi.org/10.1016/S0016-5107(90)71025-5.

    Article  CAS  PubMed  Google Scholar 

  15. Ell C, Fischbach W, Bronisch HJ, Dertinger S, Layer P, Runzi M, et al. Randomized trial of low-volume PEG solution versus standard PEG + electrolytes for bowel cleansing before colonoscopy. Am J Gastroenterol. 2008;103(4):883–93. https://doi.org/10.1111/j.1572-0241.2007.01708.x.

    Article  PubMed  Google Scholar 

  16. Corporaal S, Kleibeuker JH, Koornstra JJ. Low-volume PEG plus ascorbic acid versus high-volume PEG as bowel preparation for colonoscopy. Scand J Gastroenterol. 2010;45(11):1380–6. https://doi.org/10.3109/00365521003734158.

    Article  CAS  PubMed  Google Scholar 

  17. • Gimeno-Garcia AZ, Hernandez G, Aldea A, Nicolas-Perez D, Jimenez A, Carrillo M, et al. Comparison of two intensive bowel cleansing regimens in patients with previous poor bowel preparation: a randomized controlled study. Am J Gastroenterol 2017;112(6):951–958. https://doi.org/10.1038/ajg.2017.53. This is the first study showing a high rate of adequate cleansing with an intensive preparation regimen in patients who have had a previous poor bowel cleanse.

  18. Kang SH, Jeen YT, Lee JH, Yoo IK, Lee JM, Kim SH, et al. Comparison of a split-dose bowel preparation with 2 liters of polyethylene glycol plus ascorbic acid and 1 liter of polyethylene glycol plus ascorbic acid and bisacodyl before colonoscopy. Gastrointest Endosc. 2017;86(2):343–8. https://doi.org/10.1016/j.gie.2016.10.040.

    Article  PubMed  Google Scholar 

  19. Xie Q, Chen L, Zhao F, Zhou X, Huang P, Zhang L, et al. A meta-analysis of randomized controlled trials of low-volume polyethylene glycol plus ascorbic acid versus standard-volume polyethylene glycol solution as bowel preparations for colonoscopy. PLoS One. 2014;9(6):e99092. https://doi.org/10.1371/journal.pone.0099092.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Jung YS, Lee CK, Eun CS, Park DI, Han DS, Kim HJ. Low-volume polyethylene glycol with ascorbic acid for colonoscopy preparation in elderly patients: a randomized multicenter study. Digestion. 2016;94(2):82–91. https://doi.org/10.1159/000448887.

    Article  CAS  PubMed  Google Scholar 

  21. Mehta JB, Singhal SB, Mehta BC. Ascorbic-acid-induced haemolysis in G-6-PD deficiency. Lancet. 1990;336(8720):944. https://doi.org/10.1016/0140-6736(90)92317-B.

    Article  CAS  PubMed  Google Scholar 

  22. Siddique S, Lopez KT, Hinds AM, Ahmad DS, Nguyen DL, Matteson-Kome ML, et al. Miralax with Gatorade for bowel preparation: a meta-analysis of randomized controlled trials. Am J Gastroenterol. 2014;109(10):1566–74. https://doi.org/10.1038/ajg.2014.238.

    Article  CAS  PubMed  Google Scholar 

  23. Rex DK, Bond JH, Winawer S, Levin TR, Burt RW, Johnson DA, et al. Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol. 2002;97(6):1296–308. https://doi.org/10.1111/j.1572-0241.2002.05812.x.

    Article  PubMed  Google Scholar 

  24. Berkelhammer C, Ekambaram A, Silva RG. Low-volume oral colonoscopy bowel preparation: sodium phosphate and magnesium citrate. Gastrointest Endosc. 2002;56(1):89–94. https://doi.org/10.1067/mge.2002.125361.

    Article  PubMed  Google Scholar 

  25. Vradelis S, Kalaitzakis E, Sharifi Y, Buchel O, Keshav S, Chapman RW, et al. Addition of senna improves quality of colonoscopy preparation with magnesium citrate. World J Gastroenterol. 2009;15(14):1759–63. https://doi.org/10.3748/wjg.15.1759.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Jin Z, Lu Y, Zhou Y, Gong B. Systematic review and meta-analysis: sodium picosulfate/magnesium citrate vs. polyethylene glycol for colonoscopy preparation. Eur J Clin Pharmacol. 2016;72(5):523–32. https://doi.org/10.1007/s00228-016-2013-5.

    Article  CAS  PubMed  Google Scholar 

  27. Rex DK, DiPalma JA, McGowan J, Cleveland M. A comparison of oral sulfate solution with sodium picosulfate: magnesium citrate in split doses as bowel preparation for colonoscopy. Gastrointest Endosc. 2014;80(6):1113–23. https://doi.org/10.1016/j.gie.2014.05.329.

    Article  PubMed  Google Scholar 

  28. Park SS, Sinn DH, Kim YH, Lim YJ, Sun Y, Lee JH, et al. Efficacy and tolerability of split-dose magnesium citrate: low-volume (2 liters) polyethylene glycol vs. single- or split-dose polyethylene glycol bowel preparation for morning colonoscopy. Am J Gastroenterol. 2010;105(6):1319–26. https://doi.org/10.1038/ajg.2010.79.

    Article  CAS  PubMed  Google Scholar 

  29. Yang HJ, Park SK, Kim JH, Im JP, Yeom DH, Seo GS, et al. Randomized trial comparing oral sulfate solution with 4-L polyethylene glycol administered in a split dose as preparation for colonoscopy. J Gastroenterol Hepatol. 2017;32(1):12–8. https://doi.org/10.1111/jgh.13477.

    Article  CAS  PubMed  Google Scholar 

  30. Flemming JA, Vanner SJ, Hookey LC. Split-dose picosulfate, magnesium oxide, and citric acid solution markedly enhances colon cleansing before colonoscopy: a randomized, controlled trial. Gastrointest Endosc. 2012;75(3):537–44. https://doi.org/10.1016/j.gie.2011.09.018.

    Article  PubMed  Google Scholar 

  31. •• Johnson DA, Barkun AN, Cohen LB, Dominitz JA, Kaltenbach T, Martel M, Robertson DJ, Boland CR, Giardello FM, Lieberman DA, Levin TR, Rex DK, US Multi-Society Task Force on Colorectal Cancer. Optimizing adequacy of bowel cleansing for colonoscopy: recommendations from the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology 2014 ;147(4):903–924. https://doi.org/10.1053/j.gastro.2014.07.002. This guideline from the USMSTF provides an excellent summary of the current literature and makes evidence-based recommendations regarding bowel preparation.

  32. Martel M, Barkun AN, Menard C, Restellini S, Kherad O, Vanasse A. Split-dose preparations are superior to day-before bowel cleansing regimens: a meta-analysis. Gastroenterology. 2015;149(1):79–88. https://doi.org/10.1053/j.gastro.2015.04.004.

    Article  PubMed  Google Scholar 

  33. Enestvedt BK, Tofani C, Laine LA, Tierney A, Fennerty MB. 4-Liter split-dose polyethylene glycol is superior to other bowel preparations, based on systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2012;10(11):1225–31. https://doi.org/10.1016/j.cgh.2012.08.029.

    Article  CAS  PubMed  Google Scholar 

  34. Kilgore TW, Abdinoor AA, Szary NM, Schowengerdt SW, Yust JB, Choudhary A, et al. Bowel preparation with split-dose polyethylene glycol before colonoscopy: a meta-analysis of randomized controlled trials. Gastrointest Endosc. 2011;73(6):1240–5. https://doi.org/10.1016/j.gie.2011.02.007.

    Article  PubMed  Google Scholar 

  35. Bucci C, Rotondano G, Hassan C, Rea M, Bianco MA, Cipolletta L, Ciacci C, Marmo R Optimal bowel cleansing for colonoscopy: split the dose! A series of meta-analyses of controlled studies. Gastrointest Endosc 2014;80(4):566–576.e2, https://doi.org/10.1016/j.gie.2014.05.320.

  36. Chokshi RV, Hovis CE, Hollander T, Early DS, Wang JS. Prevalence of missed adenomas in patients with inadequate bowel preparation on screening colonoscopy. Gastrointest Endosc. 2012;75(6):1197–203. https://doi.org/10.1016/j.gie.2012.01.005.

    Article  PubMed  Google Scholar 

  37. Siddiqui AA, Yang K, Spechler SJ, Cryer B, Davila R, Cipher D, et al. Duration of the interval between the completion of bowel preparation and the start of colonoscopy predicts bowel-preparation quality. Gastrointest Endosc. 2009;69(3 Pt 2):700–6. https://doi.org/10.1016/j.gie.2008.09.047.

    Article  PubMed  Google Scholar 

  38. Seo EH, Kim TO, Park MJ, Joo HR, Heo NY, Park J, et al. Optimal preparation-to-colonoscopy interval in split-dose PEG bowel preparation determines satisfactory bowel preparation quality: an observational prospective study. Gastrointest Endosc. 2012;75(3):583–90. https://doi.org/10.1016/j.gie.2011.09.029.

    Article  PubMed  Google Scholar 

  39. Practice guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration: application to healthy patients undergoing elective procedures: an updated report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration. Anesthesiology 2017 ;126(3):376–393.

  40. Horton N, Garber A, Hasson H, Lopez R, Burke CA. Impact of single- vs. split-dose low-volume bowel preparations on bowel movement kinetics, patient inconvenience, and polyp detection: a prospective trial. Am J Gastroenterol. 2016;111(9):1330–7. https://doi.org/10.1038/ajg.2016.273.

    Article  PubMed  Google Scholar 

  41. • Cheng YL, Huang KW, Liao WC, Luo JC, Lan KH, Su CW, et al. Same-day versus split-dose bowel preparation before colonoscopy: a meta-analysis. J Clin Gastroenterol 2017. This is the most recent meta-analysis proving the superiority of a split-dose regimen over same-day bowel preparation.

  42. • Avalos DJ, Castro FJ, Zuckerman MJ, Keihanian T, Berry AC, Nutter B, Sussman DA Bowel preparations administered the morning of colonoscopy provide similar efficacy to a split dose regimen: a meta analysis. J Clin Gastroenterol 2017. https://doi.org/10.1097/MCG.0000000000000866 . This meta-analysis of 15 trials showed no difference in preparation between split dose and preparation on the morning of colonoscopy.

  43. • Nguyen DL, Jamal MM, Nguyen ET, Puli SR, Bechtold ML. Low-residue versus clear liquid diet before colonoscopy: a meta-analysis of randomized, controlled trials. Gastrointest Endosc 2016 ;83(3):499–507.e1. https://doi.org/10.1016/j.gie.2015.09.045. This meta-analysis showed no difference in preparation between low residue and clear liquid diet.,

  44. Butt J, Bunn C, Paul E, Gibson P, Brown G. The white diet is preferred, better tolerated, and non-inferior to a clear-fluid diet for bowel preparation: a randomized controlled trial. J Gastroenterol Hepatol. 2016;31(2):355–63. https://doi.org/10.1111/jgh.13078.

    Article  CAS  PubMed  Google Scholar 

  45. Stolpman DR, Solem CA, Eastlick D, Adlis S, Shaw MJ. A randomized controlled trial comparing a low-residue diet versus clear liquids for colonoscopy preparation: impact on tolerance, procedure time, and adenoma detection rate. J Clin Gastroenterol. 2014;48(10):851–5. https://doi.org/10.1097/MCG.0000000000000167.

    PubMed  Google Scholar 

  46. Sipe BW, Fischer M, Baluyut AR, Bishop RH, Born LJ, Daugherty DF, et al. A low-residue diet improved patient satisfaction with split-dose oral sulfate solution without impairing colonic preparation. Gastrointest Endosc. 2013;77(6):932–6. https://doi.org/10.1016/j.gie.2013.01.046.

    Article  PubMed  Google Scholar 

  47. Park S, Lim YJ. Adjuncts to colonic cleansing before colonoscopy. World J Gastroenterol. 2014;20(11):2735–40. https://doi.org/10.3748/wjg.v20.i11.2735.

    Article  PubMed  PubMed Central  Google Scholar 

  48. Adams WJ, Meagher AP, Lubowski DZ, King DW. Bisacodyl reduces the volume of polyethylene glycol solution required for bowel preparation. Dis Colon rectum. 1994;37(3):229–33; discussion 233-4. https://doi.org/10.1007/BF02048160.

    Article  CAS  PubMed  Google Scholar 

  49. Clark RE, Godfrey JD, Choudhary A, Ashraf I, Matteson ML, Bechtold ML. Low-volume polyethylene glycol and bisacodyl for bowel preparation prior to colonoscopy: a meta-analysis. Ann Gastroenterol. 2013;26(4):319–24.

    PubMed  PubMed Central  Google Scholar 

  50. Sharma VK, Chockalingham SK, Ugheoke EA, Kapur A, Ling PH, Vasudeva R, et al. Prospective, randomized, controlled comparison of the use of polyethylene glycol electrolyte lavage solution in four-liter versus two-liter volumes and pretreatment with either magnesium citrate or bisacodyl for colonoscopy preparation. Gastrointest Endosc. 1998;47(2):167–71. https://doi.org/10.1016/S0016-5107(98)70351-7.

    Article  CAS  PubMed  Google Scholar 

  51. Baudet JS, Castro V, Redondo I. Recurrent ischemic colitis induced by colonoscopy bowel lavage. Am J Gastroenterol. 2010;105(3):700–1. https://doi.org/10.1038/ajg.2009.637.

    Article  PubMed  Google Scholar 

  52. Ajani S, Hurt RT, Teeters DA, Bellmore LR. Ischaemic colitis associated with oral contraceptive and bisacodyl use. BMJ Case Rep 2012;2012(jul25 1):bcr1220115451. https://doi.org/10.1136/bcr-12-742-2011-5451.

  53. Wu L, Cao Y, Liao C, Huang J, Gao F. Systematic review and meta-analysis of randomized controlled trials of Simethicone for gastrointestinal endoscopic visibility. Scand J Gastroenterol. 2011;46(2):227–35. https://doi.org/10.3109/00365521.2010.525714.

    Article  PubMed  Google Scholar 

  54. Abdul-Baki H, Hashash JG, Elhajj II, Azar C, El Zahabi L, Mourad FH, et al. A randomized, controlled, double-blind trial of the adjunct use of tegaserod in whole-dose or split-dose polyethylene glycol electrolyte solution for colonoscopy preparation. Gastrointest Endosc 2008 ;68(2):294–300; quiz 334, 336, https://doi.org/10.1016/j.gie.2008.01.044.

  55. Kim HJ, Kim TO, Shin BC, Woo JG, Seo EH, Joo HR, et al. Efficacy of prokinetics with a split-dose of polyethylene glycol in bowel preparation for morning colonoscopy: a randomized controlled trial. Digestion. 2012;86(3):194–200. https://doi.org/10.1159/000339780.

    Article  PubMed  Google Scholar 

  56. Nardulli G, Limongi F, Sue G, Zapata L, Bompart I. Use of polyethylene glycol in the treatment of puerperal constipation. G E N. 1995;49(3):224–6.

    CAS  PubMed  Google Scholar 

  57. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006;131(1):283–311. https://doi.org/10.1053/j.gastro.2006.04.049.

    Article  CAS  PubMed  Google Scholar 

  58. Lai EJ, Calderwood AH, Doros G, Fix OK, Jacobson BC. The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research. Gastrointest Endosc. 2009;69(3 Pt 2):620–5. https://doi.org/10.1016/j.gie.2008.05.057.

    Article  PubMed  PubMed Central  Google Scholar 

  59. Calderwood AH, Jacobson BC. Comprehensive validation of the Boston Bowel Preparation Scale. Gastrointest Endosc. 2010;72(4):686–92. https://doi.org/10.1016/j.gie.2010.06.068.

    Article  PubMed  PubMed Central  Google Scholar 

  60. Parmar R, Martel M, Rostom A, Barkun AN. Validated scales for colon cleansing: a systematic review. Am J Gastroenterol. 2016;111(2):197–204; quiz 205. https://doi.org/10.1038/ajg.2015.417.

    Article  PubMed  Google Scholar 

  61. • Clark BT, Protiva P, Nagar A, Imaeda A, Ciarleglio MM, Deng Y, et al. Quantification of adequate bowel preparation for screening or surveillance colonoscopy in men. Gastroenterology 2016;150(2):396–405; quiz e14-5. https://doi.org/10.1053/j.gastro.2015.09.041. This study confirmed the utility of the Boston Bowel Preparation Scale core showing that lower scores are associated with increased risk of missed lesions.

  62. • Kluge MA, Williams JL, Wu CK, Jacobson BC, Schroy PC III, Lieberman DA, et al. Inadequate Boston Bowel Preparation Scale scores predict the risk of missed neoplasia on the next colonoscopy. Gastrointest Endosc 2017. https://doi.org/10.1016/j.gie.2017.06.012. This study confirmed the utility of the Boston Bowel Preparation Scale score showing that lower scores are associated with increased risk of missed lesions.

  63. Sherer EA, Imler TD, Imperiale TF. The effect of colonoscopy preparation quality on adenoma detection rates. Gastrointest Endosc. 2012;75(3):545–53. https://doi.org/10.1016/j.gie.2011.09.022

    Article  PubMed  Google Scholar 

  64. Lebwohl B, Kastrinos F, Glick M, Rosenbaum AJ, Wang T, Neugut AI. The impact of suboptimal bowel preparation on adenoma miss rates and the factors associated with early repeat colonoscopy. Gastrointest Endosc. 2011;73(6):1207–14. https://doi.org/10.1016/j.gie.2011.01.051

    Article  PubMed  PubMed Central  Google Scholar 

  65. Calderwood AH, Thompson KD, Schroy PC III, Lieberman DA, Jacobson BC. Good is better than excellent: bowel preparation quality and adenoma detection rates. Gastrointest Endosc 2015 ;81(3):691–699.e1. https://doi.org/10.1016/j.gie.2014.10.032.

  66. • Murphy CJ, Jewel Samadder N, Cox K, Iqbal R, So B, Croxford D, et al. Outcomes of next-day versus non-next-day colonoscopy after an initial inadequate bowel preparation. Dig Dis Sci 2016;61(1):46–52. https://doi.org/10.1007/s10620-015-3833-3. This large retrospective study showed a high adenoma miss rate in patients with inadequate bowel preparation.

  67. Fatima H, Johnson CS, Rex DK. Patients’ description of rectal effluent and quality of bowel preparation at colonoscopy. Gastrointest Endosc 2010 ;71(7):1244–1252.e2, https://doi.org/10.1016/j.gie.2009.11.053.

  68. Ben-Horin S, Bar-Meir S, Avidan B. The outcome of a second preparation for colonoscopy after preparation failure in the first procedure. Gastrointest Endosc. 2009;69(3 Pt 2):626–30. https://doi.org/10.1016/j.gie.2008.08.027.

    Article  PubMed  Google Scholar 

  69. Ibanez M, Parra-Blanco A, Zaballa P, Jimenez A, Fernandez-Velazquez R, Fernandez-Sordo JO, et al. Usefulness of an intensive bowel cleansing strategy for repeat colonoscopy after preparation failure. Dis Colon rectum. 2011;54(12):1578–84. https://doi.org/10.1097/DCR.0b013e31823434c8.

    Article  PubMed  Google Scholar 

  70. Hayat U, Lee PJ, Lopez R, Vargo JJ, Rizk MK. Online educational video improves bowel preparation and reduces the need for repeat colonoscopy within three years. Am J Med 2016;129(11):1219.e1–1219.e9, https://doi.org/10.1016/j.amjmed.2016.06.011.

  71. Spiegel BM, Talley J, Shekelle P, Agarwal N, Snyder B, Bolus R, et al. Development and validation of a novel patient educational booklet to enhance colonoscopy preparation. Am J Gastroenterol. 2011;106(5):875–83. https://doi.org/10.1038/ajg.2011.75.

    Article  PubMed  Google Scholar 

  72. Tian C, Champlin S, Mackert M, Lazard A, Agrawal D. Readability, suitability, and health content assessment of web-based patient education materials on colorectal cancer screening. Gastrointest Endosc. 2014;80(2):284–90. https://doi.org/10.1016/j.gie.2014.01.034.

    Article  PubMed  Google Scholar 

  73. Tae JW, Lee JC, Hong SJ, Han JP, Lee YH, Chung JH, et al. Impact of patient education with cartoon visual aids on the quality of bowel preparation for colonoscopy. Gastrointest Endosc. 2012;76(4):804–11. https://doi.org/10.1016/j.gie.2012.05.026.

    Article  PubMed  Google Scholar 

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Correspondence to Audrey H. Calderwood MD, MS.

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Cristina C. Rutherford declares that she has no conflict of interest.

Audrey H. Calderwood declares that she has no conflict of interest.

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Rutherford, C.C., Calderwood, A.H. Update on Bowel Preparation for Colonoscopy. Curr Treat Options Gastro 16, 165–181 (2018). https://doi.org/10.1007/s11938-018-0165-3

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