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Current Osteoporosis Reports

, Volume 12, Issue 3, pp 313–318 | Cite as

Fractures in Children with Cerebral Palsy

  • M. Zulf Mughal
Pediatrics (M Leonard and L Ward, Section Editors)

Abstract

Children with moderate to severe cerebral palsy are at increased risk of sustaining fracture following minimal trauma. Such fractures predominantly occur in lower limb bones and are associated with low bone mineral density. Risk factors for fracture in this group include nonambulatory status, anticonvulsant use, presence of a joint contractures, immobilization after surgery, and poor nutrition. Aims of this review are to describe the prevalence and pathogenesis of fractures in nonambulant children with cerebral palsy. Interventions and treatments that improve low bone mineral density and which may help to reduce the fracture risk in this population are also discussed.

Keywords

Cerebral palsy Fractures Bone mineral density Physical therapy Bisphosphonates 

Notes

Compliance with Ethics Guidelines

Conflict of Interest

M. Z. Mughal has received honoraria from Novartis, Alexion, and Danone.

Human and Animal Rights and Informed Consent

All studies by the author involving animal and/or human subjects were performed after approval by the appropriate institutional review boards. When required, written informed consent was obtained from all participants.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Royal Manchester Children’s HospitalCentral Manchester University Hospitals NHS Foundation TrustManchesterUK

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