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Current Diabetes Reports

, Volume 4, Issue 1, pp 53–62 | Cite as

The metabolic syndrome in children and adolescents

  • Martha L. Cruz
  • Michael I. Goran
Article

Abstract

The metabolic syndrome was recently defined by the Adult Treatment Panel III. Despite a lack of uniform definition of the syndrome in pediatrics, recent studies have shown that the syndrome develops during childhood and is highly prevalent among overweight children and adolescents. The hypothesized central role of insulin resistance and obesity as a common underlying feature of the metabolic syndrome also appears to be already manifested in childhood. In view of the current obesity epidemic in children and adolescents, there is a vital need to provide adequate guidelines for the definition of the metabolic syndrome in pediatrics and for the development of screening and treatment strategies. This article focuses on the above issues, as well as on the impact of the syndrome on two major disease outcomes, type 2 diabetes and cardiovascular disease.

Keywords

Insulin Resistance Metabolic Syndrome Impaired Glucose Tolerance Impaired Fasting Glucose National Cholesterol Education Program 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Current Science Inc 2004

Authors and Affiliations

  • Martha L. Cruz
    • 1
  • Michael I. Goran
    • 1
  1. 1.Department of Preventive Medicine, Physiology and Biophysics, Keck School of MedicineUniversity of Southern CaliforniaLos AngelesUSA

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