Abstract
Objective: To investigate the relationship between the prognosis of Epithelial Ovarian Cancer (EOC) and its ascites. Methods: Retrospectively analysis is performed for the clinical, pathological and followed up data of 101 in-patients suffering from epithelial ovarian cancer and operated with tumor debulking surgery in our hospital from January 1986 to December 1993. The patients was divided into two groups based upon the first laparotomy finding with ascites(62) or without(39). Age average, cell type, advanced proportion and survival rate of the patients are evaluated by a χ2 test. Results: For age average and cell type, no statistical difference was noted. However, there were more advanced cases in ascites group than in the other (P<0.01). The 3-, 4- and 5-year survival in the no-ascites group were 87.02%, 73.42%, 57.10% respectively compared with 65.02%, 38.66%, 28.12% in the ascites group. The 5-year survival rate of stage I, II,III, IV patients in no-ascites group are 77%, 70%, 41.1%, 0 respectively, compared with that of 60%, 56.8%, 15.46%, 0 respectively in the ascites group. The results shows that 3-, 4-, and 5-year survival in no-ascites group were significantly higher than those in ascites group(P<0.01). Conclusion: Presence of ascites is a factor of poor prognosis for EOC.
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Feldman GB, Knapp RC, Order SE, et al. The role of lymphatic obstraction in the formation of ascites in a murine ovarine carcinoma[J]. Cancer Res 1972; 32: 1663.
Bolis G, Villa A, Guamerio P, et al. Survival of women with advanced ovarian cancer and complete pathologic response at second-look laparotomy[J]. Cancer 1996; 77: 128.
Schilder RJ, Boente MP, Com BW, et al. The management of early ovarian cancer[J]. Oncology-Hunting 1995; 9: 171.
Kosary CL. FIGO stage, histology, histologic grade, age and race as prognostic factors in determining survival for cancers of the female gynecological system: an analysis of 1973–1987 SEER cases of cancers of the endometrium, cervix, ovary, vulva and vagina[J]. Semin Surg Oncol 1994; 10: 31.
Sainz de la Cuesta R, Goff BA, Fuller AF, et al. Prognostic importance of intraoperative rupture of malignant ovarian epithelial neoplasms[J]. Obstet Gynecol 1994; 84: 1.
Sliutz G. Prognostic factors in ovarian carcinoma[J]. Wien Med Wochenschr 1996; 146: 14.
Ahmed FY, Wiltshaw E, A’Hem RP, et al. Natural history and prognosis of untreated stage I epithelial ovarian carcinoma[J]. J Clin Oncol 1996; 14: 2968.
Puls LE, duniho T, Hunter JE, et al. The prognostic implication of ascites in advanced-stage ovarian cancer[J]. Gynecol Oncol 1996; 61: 109.
Finn CB, Luesley DM, Buxton EJ, et al. Is stage I Epithelial ovarial ovarian cancer overtreated both surgically and systemically? Results of a five-year cancer registry review[J]. Br J Obstet Gynaecol 1992; 99: 54.
Colozza M, Mosconi AM, Gori S, et al. Long-term results in patients with advanced epithelial ovarian carcinoma treated with a combination of cisplatin, doxorubicin, and cyclophosphamide[J]. AM J Clin Oncol 1997; 20: 552.
Zhang GN, Song SQ, Yu J, et al. Intraperitoneal cisplatin and etopside combine with intravenous cyclophosphamide chemotherapy treated epithelial ovarian carcinoma[J]. Chin J Oncol 1996; 18: 87.
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Biography: Song Shui-qin, (1965–), associate professor, Sichuan Province Cancer Hospital, majors in gynecologic oncology.
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Song, Sq., Zhang, Gn., Wu, Yl. et al. Prognosis of epithelial ovarian cancer related to its ascites. Chin. J. Cancer Res. 13, 151–154 (2001). https://doi.org/10.1007/s11670-001-0036-6
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DOI: https://doi.org/10.1007/s11670-001-0036-6