Journal of Gastrointestinal Surgery

, Volume 11, Issue 4, pp 452–457 | Cite as

Management of Hepatic Angiomyolipoma

  • Ching-Yao Yang
  • Ming-Chih Ho
  • Yung-Ming Jeng
  • Rey-Heng Hu
  • Yao-Ming Wu
  • Po-Huang Lee


Preoperative diagnosis of hepatic angiomyolipoma is difficult, and the treatment for it remains controversial. The aim of this study is to review our experience in the treatment of hepatic angiomyolipoma and to propose a treatment strategy for this disease. We retrospectively collected the clinical, imaging, and pathological features of patients with hepatic angiomyolipoma. Immunohistochemical studies with antibodies for HMB-45, actin, S-100, cytokeratin, vimentin, and c-kit were performed. Treatment experience and long-term follow-up results are summarized. During a period of 9 years, 10 patients with hepatic angiomyolipoma were treated at our hospital. There was marked female predominance (nine patients). Nine patients received surgical resection without complications. One patient received nonoperative management with biopsy and follow-up. One patient died 11 months after surgery because of recurrent disease. We propose all symptomatic patients should receive surgical resection for hepatic angiomyolipoma. Conservative management with close follow-up is suggested in patients with asymptomatic tumors and meet the following criteria: (1) tumor size smaller than 5 cm, (2) angiomyolipoma proved through fine needle aspiration biopsy, (3) patients with good compliance, and (4) not a hepatitis virus carrier.


Angiomyolipoma Hepatic angiomyolipoma Liver tumor 



The authors would like to thank Dr. Kao-Lung Liu (Department of Radiology, National Taiwan University Hospital) for assistance with Fig. 1 and interpretation of radiologic pictures.


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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Ching-Yao Yang
    • 1
    • 2
  • Ming-Chih Ho
    • 1
  • Yung-Ming Jeng
    • 3
  • Rey-Heng Hu
    • 1
  • Yao-Ming Wu
    • 1
  • Po-Huang Lee
    • 1
  1. 1.Department of SurgeryNational Taiwan University Hospital, and National Taiwan University College of MedicineTaipeiTaiwan
  2. 2.Department of TraumatologyNational Taiwan University Hospital, and National Taiwan University College of MedicineTaipeiTaiwan
  3. 3.Department of PathologyNational Taiwan University Hospital, and National Taiwan University College of MedicineTaipeiTaiwan

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