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Laser therapy for recurrent aphthous stomatitis: an overview

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Abstract

Objectives

To evaluate therapeutic effects of laser therapy on patients with recurrent aphthous stomatitis assessing evidences from previously published systematic reviews.

Materials and methods

An overview of systematic reviews was conducted based on PRISMA checklist. Search strategies were developed and adapted for six different electronic databases and a gray literature search was also performed. The methodology quality of the included systematic reviews was assessed by the Measurement Tool to Assess the Methodological Quality of Systematic Reviews 2 (AMSTAR 2).

Results

After a two-step selection, five systematic reviews were included. Methodology quality was considered as a high risk of bias in two systematic reviews, while in the other three were graded as moderate. The systematic reviews’ conclusions demonstrated that all included systematics reviews showed positive effects of laser therapy for pain relief, and most of them demonstrated healing improvement. A meta-analysis was not feasible due to heterogeneity in treatments parameters.

Conclusions

Evidence suggested that laser therapy is an effective tool to treat recurrent aphthous stomatitis; nevertheless, more randomized clinical trials should be conducted to compare different lasers parameters.

Clinical relevance

The present overview evaluated recent evidence about laser therapy for recurrent aphthous stomatitis management in order to contribute for evidence-based dentistry and decision-making. This overview suggests that laser therapy is a safe and promising alternative to treat recurrent aphthous stomatitis, since it promotes wound healing and pain relief.

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Authors and Affiliations

  1. Laboratory of Oral Histopathology, Health Sciences Faculty, University of Brasilia, Asa Norte, Brasilia, DF, 70910-900, Brazil

    Juliana Amorim dos Santos, Ana Gabriela Costa Normando, Isabela Porto de Toledo & Eliete Neves Silva Guerra

  2. Brazilian Centre for Evidence-Based Research, Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil

    Isabela Porto de Toledo, Gilberto Melo & Graziela De Luca Canto

  3. Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), São Paulo, Brazil

    Alan Roger Santos-Silva

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  1. Juliana Amorim dos Santos
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Correspondence to Eliete Neves Silva Guerra.

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Amorim dos Santos, J., Normando, A.G.C., de Toledo, I.P. et al. Laser therapy for recurrent aphthous stomatitis: an overview. Clin Oral Invest 24, 37–45 (2020). https://doi.org/10.1007/s00784-019-03144-z

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