Child's Nervous System

, Volume 28, Issue 7, pp 1091–1097 | Cite as

Battery life following pallidal deep brain stimulation (DBS) in children and young people with severe primary and secondary dystonia

  • Daniel E. Lumsden
  • Margaret Kaminska
  • Kylie Tustin
  • Hortensia Gimeno
  • Lesley Baker
  • Keyoumars Ashkan
  • Richard Selway
  • Jean-Pierre Lin
Original Paper

Abstract

Background

The finite life of non-rechargeable batteries powering implantable pulse generators (IPG) necessitates their periodic replacement. Children receiving deep brain stimulation (DBS) may require frequent battery changes over their treatment lifetime.

Objectives

We aimed to determine the battery life of IPGs used in pallidal DBS for the treatment of dystonia in children and young people.

Methods

We make use of a review of case notes of all children and young people undergoing DBS surgery at our institution from June 2005 to May 2010.

Results

A total of 54 children and young people underwent surgery on at least one occasion, with a total of 76 IPGs implanted. Replacement IPGs due to battery failure were required in 15 out of 54 (27.8%). The average time to battery failure was 24.5 ± 2.9 months (95% confidence interval), with a range of 13–39 months. Battery life was significantly longer in primary compared to subsequent IPGs. No difference in longevity was seen between different IPG devices.

Conclusions

IPG battery life may be short in children and young people receiving treatment for dystonia. These findings highlight the potential benefits of the recently introduced rechargeable neurostimulators.

Keywords

Dystonia Pallidal Deep brain stimulation Battery 

Notes

Acknowledgments

This work was supported by a grant from the Guy’s and St Thomas’ Charity: Project Number G06070.

References

  1. 1.
    Allert N, Kirsch H, Weirich W, Karbe H (2009) Stability of symptom control after replacement of impulse generators for deep brain stimulation. J Neurosurg 110:1274–1277PubMedCrossRefGoogle Scholar
  2. 2.
    Alterman RL, Miravite J, Weisz D, Shils JL, Bressman SB, Tagliati M (2007) Sixty hertz pallidal deep brain stimulation for primary torsion dystonia. Neurology 69:681–688PubMedCrossRefGoogle Scholar
  3. 3.
    Alterman RL, Shils JL, Miravite J, Tagliati M (2007) Lower stimulation frequency can enhance tolerability and efficacy of pallidal deep brain stimulation for dystonia. Mov Disord 22:366–368PubMedCrossRefGoogle Scholar
  4. 4.
    Andrews C, Aviles-Olmos I, Hariz M, Foltynie T (2010) Which patients with dystonia benefit from deep brain stimulation? A metaregression of individual patient outcomes. J Neurol Neurosurg Psychiatry 81:1383–1389PubMedCrossRefGoogle Scholar
  5. 5.
    Anheim M, Fraix V, Chabardes S, Krack P, Benabid AL, Pollak P (2007) Lifetime of Itrel II pulse generators for subthalamic nucleus stimulation in Parkinson’s disease. Mov Disord 22:2436–2439PubMedCrossRefGoogle Scholar
  6. 6.
    Anheim M, Vercueil L, Fraix V, Chabardes S, Seigneuret E, Krack P, Benabid AL, Vidailhet M, Pollak P (2008) Early stimulation of DYT1 primary generalized dystonia prevents from its secondary irreversible complications. Mov Disord 23:2261–2263PubMedCrossRefGoogle Scholar
  7. 7.
    Blahak C, Capelle HH, Baezner H, Kinfe TM, Hennerici MG, Krauss JK (2011) Battery lifetime in pallidal deep brain stimulation for dystonia. Eur J Neurol 18:872–875PubMedCrossRefGoogle Scholar
  8. 8.
    Chou KL, Siderowf AD, Jaggi JL, Liang GS, Baltuch GH (2004) Unilateral battery depletion in Parkinson’s disease patients treated with bilateral subthalamic nucleus deep brain stimulation may require urgent surgical replacement. Stereotact Funct Neurosurg 82:153–155PubMedCrossRefGoogle Scholar
  9. 9.
    Coubes P, Cif L, El Fertit H, Hemm S, Vayssiere N, Serrat S, Picot MC, Tuffery S, Claustres M, Echenne B, Frerebeau P (2004) Electrical stimulation of the globus pallidus internus in patients with primary generalized dystonia: long-term results. J Neurosurg 101:189–194PubMedCrossRefGoogle Scholar
  10. 10.
    Goto S, Mita S, Ushio Y (2002) Bilateral pallidal stimulation for cervical dystonia. An optimal paradigm from our experiences. Stereotact Funct Neurosurg 79:221–227PubMedCrossRefGoogle Scholar
  11. 11.
    Halbig TD, Gruber D, Kopp UA, Schneider GH, Trottenberg T, Kupsch A (2005) Pallidal stimulation in dystonia: effects on cognition, mood, and quality of life. J Neurol Neurosurg Psychiatry 76:1713–1716PubMedCrossRefGoogle Scholar
  12. 12.
    Isaias IU, Alterman RL, Tagliati M (2008) Outcome predictors of pallidal stimulation in patients with primary dystonia: the role of disease duration. Brain 131:1895–1902PubMedCrossRefGoogle Scholar
  13. 13.
    Isaias IU, Alterman RL, Tagliati M (2009) Deep brain stimulation for primary generalized dystonia: long-term outcomes. Arch Neurol 66:465–470PubMedCrossRefGoogle Scholar
  14. 14.
    Krause M, Fogel W, Kloss M, Rasche D, Volkmann J, Tronnier V (2004) Pallidal stimulation for dystonia. Neurosurgery 55:1361–1368PubMedCrossRefGoogle Scholar
  15. 15.
    Kupsch A, Benecke R, Muller J, Trottenberg T, Schneider GH, Poewe W, Eisner W, Wolters A, Muller JU, Deuschl G, Pinsker MO, Skogseid IM, Roeste GK, Vollmer-Haase J, Brentrup A, Krause M, Tronnier V, Schnitzler A, Voges J, Nikkhah G, Vesper J, Naumann M, Volkmann J (2006) Pallidal deep-brain stimulation in primary generalized or segmental dystonia. N Engl J Med 355:1978–1990PubMedCrossRefGoogle Scholar
  16. 16.
    Moro E, Piboolnurak P, Arenovich T, Hung SW, Poon YY, Lozano AM (2009) Pallidal stimulation in cervical dystonia: clinical implications of acute changes in stimulation parameters. Eur J Neurol 16:506–512PubMedCrossRefGoogle Scholar
  17. 17.
    Ondo WG, Meilak C, Vuong KD (2007) Predictors of battery life for the Activa Soletra 7426 Neurostimulator. Parkinsonism Relat Disord 13:240–242PubMedCrossRefGoogle Scholar
  18. 18.
    Parr JR, Green AL, Joint C, Andrew M, Gregory RP, Scott RB, McShane MA, Aziz TZ (2007) Deep brain stimulation in childhood: an effective treatment for early onset idiopathic generalised dystonia. Arch Dis Child 92:708–711PubMedCrossRefGoogle Scholar
  19. 19.
    Van Buyten JP, Fowo S, Spincemaille GH, Tronnier V, Beute G, Pallares JJ, Naous H, Zucco F, Krauss JK, De Andres J, Buchser E, Costantini A, Lazorthes Y (2008) The restore rechargeable, implantable neurostimulator: handling and clinical results of a multicenter study. Clin J Pain 24:325–334PubMedCrossRefGoogle Scholar
  20. 20.
    Vasques X, Cif L, Gonzalez V, Nicholson C, Coubes P (2009) Factors predicting improvement in primary generalized dystonia treated by pallidal deep brain stimulation. Mov Disord 24:846–853PubMedCrossRefGoogle Scholar
  21. 21.
    Vidailhet M, Vercueil L, Houeto JL, Krystkowiak P, Benabid AL, Cornu P, Lagrange C, du Tezenas MS, Dormont D, Grand S, Blond S, Detante O, Pillon B, Ardouin C, Agid Y, Destee A, Pollak P (2005) Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia. N Engl J Med 352:459–467PubMedCrossRefGoogle Scholar
  22. 22.
    Vidailhet M, Vercueil L, Houeto JL, Krystkowiak P, Lagrange C, Yelnik J, Bardinet E, Benabid AL, Navarro S, Dormont D, Grand S, Blond S, Ardouin C, Pillon B, Dujardin K, Hahn-Barma V, Agid Y, Destee A, Pollak P (2007) Bilateral, pallidal, deep-brain stimulation in primary generalised dystonia: a prospective 3 year follow-up study. Lancet Neurol 6:223–229PubMedCrossRefGoogle Scholar
  23. 23.
    Vidailhet M, Yelnik J, Lagrange C, Fraix V, Grabli D, Thobois S, Burbaud P, Welter ML, Xie-Brustolin J, Braga MC, Ardouin C, Czernecki V, Klinger H, Chabardes S, Seigneuret E, Mertens P, Cuny E, Navarro S, Cornu P, Benabid AL, Le Bas JF, Dormont D, Hermier M, Dujardin K, Blond S, Krystkowiak P, Destee A, Bardinet E, Agid Y, Krack P, Broussolle E, Pollak P (2009) Bilateral pallidal deep brain stimulation for the treatment of patients with dystonia-choreoathetosis cerebral palsy: a prospective pilot study. Lancet Neurol 8:709–717PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Daniel E. Lumsden
    • 1
  • Margaret Kaminska
    • 1
  • Kylie Tustin
    • 1
  • Hortensia Gimeno
    • 1
  • Lesley Baker
    • 1
  • Keyoumars Ashkan
    • 2
  • Richard Selway
    • 2
  • Jean-Pierre Lin
    • 1
  1. 1.Complex Motor Disorder Service, Evelina Children’s HospitalGuy’s and St Thomas’ NHS Foundation TrustLondonUK
  2. 2.Functional NeurosurgeryKing’s College Hospital NHS Foundation TrustLondonUK

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