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Die bulbäre Harnröhrenstriktur

Banale urologische Erkrankung oder chirurgische Herausforderung?

Bulbar urethral strictures

A trivial urological disease or a surgical challenge?

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Zusammenfassung

Harnröhrenstrikturen befinden sich in der Mehrzahl der Fälle in der bulbären Harnröhre und sind dort meistens durch ein Trauma bedingt. Sie können radiologisch einfach und sicher diagnostiziert werden. Bei kurzstreckigen Erstbefunden kann eine einfache Sachse-Urethrotomie bereits zu einer dauerhaften Sanierung der Erkrankung führen. Im Falle eines Rezidivs sollte jedoch ein offen-operatives Verfahren angewendet werden, da ansonsten keine Heilung mehr erreicht werden kann. Dabei kommen in Abhängigkeit vom Befund und der Begleiterkrankungen die End-zu-End-Anastomose, die Graft- oder Flap-Urethroplastik oder die perineale Urethrostomie in Frage. Bei Verzögerung der offen-chirurgischen Therapie kommt es zu einer Aggravierung des Befunds und zu einer Verschlechterung der Prognose der Erkrankung – unabhängig von der dann angewendeten Therapie.

Abstract

Urethral strictures are often located in the bulbar urethra, and bulbar strictures are commonly due to urethral trauma. Diagnosis is confirmed by radiographic imaging of the urethra. In cases of short primary bulbar strictures, a simple internal urethrotomy may be curative. In contrast, open surgery should be performed in long segment or recurrent strictures because recurrence rates are near 100% in these cases. Depending of the actual findings and comorbidities, end-to-end anastomosis, graft urethroplasty, flap urethroplasty, or perineal urethrostomy may be used. If definitive treatment using open surgery is delayed and multiple endoscopic treatments are tried, urethroplasty becomes more complex and success rates of definitive treatment decline.

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Literatur

  1. Andrich DE, Mundy AR (2012) Non-transecting anastomotic bulbar urethroplasty: a preliminary report. BJU Int 109:1090–1094

    Article  PubMed  Google Scholar 

  2. Anger JT, Buckley JC, Santucci RA et al (2011) Trends in stricture management among male medicare beneficiaries: underuse of urethroplasty? Urology 77:481–485

    Article  PubMed  Google Scholar 

  3. Barbagli G, Palminteri E, Guazzoni G et al (2005) Bulbar urethroplasty using buccal mucosa grafts placed on the ventral, dorsal or lateral surface of the urethra: are results affected by the surgical technique? J Urol 174:955–957 (discussion 957–958)

    Article  PubMed  Google Scholar 

  4. Barbagli G, De Angelis M, Romano G et al (2007) Long-term followup of bulbar end-to-end anastomosis: a retrospective analysis of 153 patients in a single center experience. J Urol 178:2470–2473

    Article  PubMed  Google Scholar 

  5. Barbagli G, Guazzoni G, Lazzeri M (2008) One-stage bulbar urethroplasty: retrospective analysis of the results in 375 patients. Eur Urol 53:828–833

    Article  PubMed  Google Scholar 

  6. Barbagli G, Morgia G, Lazzeri M (2008) Retrospective outcome analysis of one-stage penile urethroplasty using a flap or graft in a homogeneous series of patients. BJU Int 102:853–860

    Article  PubMed  Google Scholar 

  7. Barbagli G, De Angelis M, Romano G et al (2009) Clinical outcome and quality of life assessment in patients treated with perineal urethrostomy for anterior urethral stricture disease. J Urol 182:548–557

    Article  PubMed  Google Scholar 

  8. Barbagli G, Montorsi F, Guazzoni G et al (2013) Ventral oral mucosal onlay graft urethroplasty in nontraumatic bulbar urethral strictures: surgical technique and multivariable analysis of results in 214 patients. Eur Urol 64:440–447

    Article  PubMed  Google Scholar 

  9. Barbagli G, Kulkarni SB, Fossati N et al (2014) Long-term followup and deterioration rate of anterior substitution urethroplasty. J Urol 192:808–813

    Article  PubMed  Google Scholar 

  10. Blaschko SD, Mcaninch JW, Myers JB et al (2012) Repeat urethroplasty after failed urethral reconstruction: outcome analysis of 130 patients. J Urol 188:2260–2264

    Article  PubMed  PubMed Central  Google Scholar 

  11. Breyer BN, Mcaninch JW, Whitson JM et al (2010) Multivariate analysis of risk factors for long-term urethroplasty outcome. J Urol 183:613–617

    Article  PubMed  Google Scholar 

  12. Buckley JC, Zinman LN (2012) Removal of endoprosthesis with urethral preservation and simultaneous urethral reconstruction. J Urol 188:856–860

    Article  PubMed  Google Scholar 

  13. Chapman D, Kinnaird A, Rourke K (2017) Independent predictors of stricture recurrence following urethroplasty for isolated bulbar urethral strictures. J Urol 198(5):1107–1112. https://doi.org/10.1016/j.juro.2017.05.006

    Article  PubMed  Google Scholar 

  14. Farrell MR, Lawrenz CW, Levine LA (2017) Internal urethrotomy with intralesional mitomycin C: an effective option for endoscopic management of recurrent bulbar and bulbomembranous urethral strictures. Urology. https://doi.org/10.1016/j.urology.2017.07.017

    PubMed  Google Scholar 

  15. Fossati N, Barbagli G, Larcher A et al (2016) The surgical learning curve for one-stage anterior urethroplasty: a prospective single-surgeon study. Eur Urol 69:686–690

    Article  PubMed  Google Scholar 

  16. Greenwell TJ, Castle C, Andrich DE et al (2004) Repeat urethrotomy and dilation for the treatment of urethral stricture are neither clinically effective nor cost-effective. J Urol 172:275–277

    Article  CAS  PubMed  Google Scholar 

  17. Hussein MM, Moursy E, Gamal W et al (2011) The use of penile skin graft versus penile skin flap in the repair of long bulbo-penile urethral stricture: a prospective randomized study. Urology 77:1232–1237

    Article  PubMed  Google Scholar 

  18. Lumen N, Poelaert F, Oosterlinck W et al (2016) Nontransecting anastomotic repair in urethral reconstruction: surgical and functional outcomes. J Urol 196:1679–1684

    Article  PubMed  Google Scholar 

  19. Mandhani A, Chaudhury H, Kapoor R et al (2005) Can outcome of internal urethrotomy for short segment bulbar urethral stricture be predicted? J Urol 173:1595–1597

    Article  PubMed  Google Scholar 

  20. Pansadoro V, Emiliozzi P (1996) Internal urethrotomy in the management of anterior urethral strictures: long-term followup. J Urol 156:73–75

    Article  CAS  PubMed  Google Scholar 

  21. Rosenbaum CM, Schmid M, Ludwig TA et al (2016) Redo buccal mucosa graft urethroplasty: success rate, oral morbidity and functional outcomes. BJU Int 118:797–803

    Article  PubMed  Google Scholar 

  22. Steenkamp JW, Heyns CF, De Kock ML (1997) Internal urethrotomy versus dilation as treatment for male urethral strictures: a prospective, randomized comparison. J Urol 157:98–101

    Article  CAS  PubMed  Google Scholar 

  23. Strittmatter F, Beck V, Stief CG, Tritschler S (2017) Urethrastriktur – Von der Diagnostik bis zur sinnvollen Therapie. Urologe 56:1047–1057

    Article  CAS  PubMed  Google Scholar 

  24. Tritschler S, Roosen A, Fullhase C et al (2013) Urethral stricture: etiology, investigation and treatments. Dtsch Arztebl Int 110:220–226

    PubMed  PubMed Central  Google Scholar 

  25. Viers BR, Pagliara TJ, Shakir NA et al (2017) Delayed reconstruction of bulbar urethral strictures is associated with multiple interventions, longer strictures, and more complex repairs. J Urol. https://doi.org/10.1016/j.juro.2017.08.081

    PubMed  Google Scholar 

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Correspondence to M. Austen.

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M. Austen, J. Breul und S. Tritschler geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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Austen, M., Breul, J. & Tritschler, S. Die bulbäre Harnröhrenstriktur. Urologe 57, 17–20 (2018). https://doi.org/10.1007/s00120-017-0545-7

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