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Study of the effects of chemotherapy on auditory function

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Indian Journal of Otolaryngology and Head and Neck Surgery Aims and scope Submit manuscript

Abstract

Chemotherapeutic agents are known to cause multiple toxicities such as myelotoxicity, nephrotoxicity and ototoxicity. A prospective study was carried out on 60 patients receiving Cisplatin based chemotherapy in a tertiary care centre. The effects of Cisplatin on auditory function were studied using metabolic, biochemical and audiological parameters. The auditory effects were correlated with the dose and duration of chemotherapy. The study concluded that a significant percentage (15%) of patients who were subjected to chemotherapy based on Cisplatin developed high frequency sensorineural hearing loss which was permanent and irreversible in nature.

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Authors and Affiliations

  1. 7, Air force Hospital, Mathur Singh Road, 208 004, Kanpur

    A Dutta (Graded specialist ENT), M D Venkatesh (Graded specialist ENT) & R C Kashyap (Graded specialist ENT)

Authors
  1. A Dutta
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  2. M D Venkatesh
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  3. R C Kashyap
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Dutta, A., Venkatesh, M.D. & Kashyap, R.C. Study of the effects of chemotherapy on auditory function. Indian J Otolaryngol Head Neck Surg 57, 226–228 (2005). https://doi.org/10.1007/BF03008019

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  • DOI: https://doi.org/10.1007/BF03008019

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