Abstract
Spinel-structured manganese (Mn)-nickel (Ni)-ferrite nanoparticles were synthesized using a chemical co-precipitation method. Coating with PEG (polyethylene glycol) was simultaneously conducted along with the synthesis of Mn-Ni-ferrites. The X-ray diffraction (XRD) and the Fourier-transform infrared (FTIR) analyses revealed a cubic spinel ferrite structure of the synthesized nanoparticles. Transmission electron microscopy (TEM) images showed that the synthesized nanoparticles were rod-shaped with a uniform size distribution and that the average length and width were 15.13 ± 1.32 nm and 3.78 ± 0.71 nm, respectively. The bonding status of PEG on the nanoparticle surface was checked by using FTIR. The relaxivities of the hydrogen protons in the aqueous solutions of the coated particles were determined by using nuclear magnetic resonance (NMR) spectrometry. The T1 and the T2 relaxivities were 0.34 ± 0.11 mM−1s−1 and 29.91 ± 0.98 mM−1s−1, respectively. This indicates that the synthesized PEG-coated Mn-Ni-ferrite nanoparticles are suitable for use as T2 contrast agents.
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Iqbal, Y., Bae, H., Rhee, I. et al. Relaxivities of hydrogen protons in aqueous solutions of PEG-coated rod-shaped manganese-nickel-ferrite (Mn0.4Ni0.6Fe2O4) nanoparticles. Journal of the Korean Physical Society 65, 1594–1597 (2014). https://doi.org/10.3938/jkps.65.1594
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DOI: https://doi.org/10.3938/jkps.65.1594