The development of the Universe from its earliest beginnings is regarded as a succession of symmetry-breakings.... The phenomenon of life also fits naturally into this picture. Life too is symmetry-breaking.... Every time a symmetry is broken, new levels of diversity and creativity become possible. It may be that the nature of our universe and the nature of life are such that this process of diversification will have no end.
Freeman John Dyson, Infinite in All Directions (1988)
Abstract
A new pattern of regularity in the formation of chiral molecular biological system hierarchical structures is found. The formation of structures with alternating chirality (spiral structures) allows their stratification. Special attention is given to the emergence of chiral patterns in active media, and to the alternating chiral hierarchies in molecular machine structures (proteins and nucleic acids).
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References
Nikolis, G. and Prigogine, I., Self-Organization in Nonequilibrium Systems: from Dissipative Structures to Order through Fluctuations, New York, 1977.
Shrodinger, E., What Is Life? The Physical Aspects of a Living Cell, Cambridge Univ. Press, 1944.
Blyumenfel’d, L.A., Reshaemye i nereshaemye problemy biologicheskoi fiziki (Solvable and Nonsolvable Problems of Biological Physics), Moscow: Editorial URSS, 2002.
Tverdislov, V.A., Biophysics, 2013, vol. 58, no. 1, p. 128.
Tverdislov, V.A. and Yakovenko, L.V., Moscow Univ. Phys. Bull., 2008, vol. 63, no. 3, p. 151.
Waigh, T.A., Applied Biophysics: A Molecular Approach for Physical Scientists, Wiley-Interscience, 2007.
Blumenfeld, L.A. and Tikhonov, A.N., Biophysical Thermodynamics of Intracellular Processes. Molecular Machines of the Living Cell, New York: Springer-Verlag, 1994.
Finkel’shtein, A.V. and Ptitsyn, O.B., Fizika belka: Kurs lektsii s tsvetnymi i stereoskopicheskimi illyustratsiyami i zadachami (Protein Physics. Lecture Course with Colored Stereoscopic Pictures and Problems), Moscow: KDU, 2005, 3rd ed.
Tverdislov, V.A., Sidorova, A.E., and Yakovenko, L.V., Biofizicheskaya ekologiya (Biophysical Ecology), Moscow: URSS, KRASAND, 2012.
Zhabotinskii, A.M., Kontsentratsionnye kolebaniya (Concentration Oscillations), Moscow: Nauka, 1974.
Vanag, V.K., Dissipativnye struktury v reaktsionno-diffuzionnykh sistemakh. Eksperiment i teoriya (Dissipative Structures in Reaction-Diffusion Systems. Experiment and Theory), Moscow: RCD, 2008.
Prigogine, I. and Kondepudi, D., Modern Thermodynamics, John Wiley & Sons, 1998.
Poptsova, M.S., Autowaves transformation in locally inhomogeneous active mediums, Cand. Sci. (Phys.–Math.) Dissertation, Moscow: Moscow State Univ., 2004.
Blyumenfel’d, L.A., Ross. Khim. Zh., 1999, vol. 43, no. 5, p. 15.
Chernavskii, D.S. and Chernavskaya, N.M., Belokmashina: Biologicheskie makromolekulyarnye konstruktsii (Proteine Machine: Biological Macromolecular Structures), Moscow: Mosk. Gos. Univ., 1999.
Tverdislov, V.A., Chirality as an instrument of stratification of hierarchical systems in animate and inanimate nature, arXiv: 1212.1677.
www.rcsb.org/
http://coiledcoils.chm.bris.ac.uk/ccplus/search/
Lupas, A. and Gruber, M., Adv. Protein Chem., 2005, vol. 70, p. 37.
https://en.wikipedia.org/wiki/Myosin
https://en.wikipedia.org/wiki/Actin
https://en.wikipedia.org/wiki/Troponin
Levinthal, C., Proc. Meeting Held at Allerton House, Monticello, Illinois, De Brunner, J.T.P. and Munck, E., Eds., Univ. of Illinois, 1969, pp. 22–24.
Plasson, R., Kondepudi, D.K., Bersini, H., et al., Chirality, 2007, vol. 19, p. 589.
Wagnière, G.H., On Chirality and the Universal Asymmetry. Reflections on Image and Mirror Image, Zurich: Verlag Helvetica Chimica Acta, 2007, p. 247.
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Original Russian Text © V.A. Tverdislov, E.V. Malyshko, S.A. Ilchenko, 2015, published in Izvestiya Rossiiskoi Akademii Nauk. Seriya Fizicheskaya, 2015, Vol. 79, No. 12, pp. 1728–1732.
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Tverdislov, V.A., Malyshko, E.V. & Ilchenko, S.A. From autowave mechanisms of self-assembly to molecular machines. Bull. Russ. Acad. Sci. Phys. 79, 1516–1520 (2015). https://doi.org/10.3103/S1062873815120230
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DOI: https://doi.org/10.3103/S1062873815120230