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Complementary Use of LC-ICP-MS and LC-ESI-Q-TOF-MS for Selenium Speciation

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Abstract

We demonstrated the complementary use of inductively coupled plasma–mass spectrometry (ICP-MS) and electrospray ionization quadrupole time-of-flight mass spectrometry (ESI-Q-TOF-MS) for the analysis of Se-containing compounds, such as selenate, selenomethionine (SeMet), and trimethylselenonium ion (TMSe), found in biological samples. The sensitivity of ESI-Q-TOF-MS for Se-containing compounds was strongly dependent on the chemical species. ICP-MS exhibited higher sensitivity than ESI-Q-TOF-MS, and had no species dependency. On the other hand, ESI-Q-TOF-MS enabled easy and robust identification of Se-containing compounds.

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References

  1. K. T. Suzuki and Y. Ogra, Food Addit. Contam., 2002, 19, 974.

    Article  CAS  PubMed  Google Scholar 

  2. P. D. Whanger, J. Am. Coll. Nutr., 2002, 21, 223.

    Article  CAS  PubMed  Google Scholar 

  3. A. Bock, L. Flohe and J. Kohrle, Biol. Chem., 2007, 388, 985.

    Article  PubMed  Google Scholar 

  4. R. F. Burk and K. E. Hill, Annu. Rev. Nutr., 2005, 25, 215.

    Article  CAS  PubMed  Google Scholar 

  5. Y. Ogra and Y. Anan, J. Anal. At. Spectrom., 2009, 24, 1477.

    Article  CAS  Google Scholar 

  6. J. S. Becker and N. Jakubowski, Chem. Soc. Rev., 2009, 38, 1969.

    Article  CAS  PubMed  Google Scholar 

  7. J. Szpunar and R. Lobinski, Anal. Bioanal. Chem., 2002, 373, 404.

    Article  CAS  PubMed  Google Scholar 

  8. A. Prange and D. Pröfrock, Anal. Bioanal. Chem., 2005, 383, 372.

    Article  CAS  PubMed  Google Scholar 

  9. J. Szpunar, Analyst, 2005, 130, 442.

    Article  CAS  PubMed  Google Scholar 

  10. L. Bendahl and B. Gammelgaard, J. Anal. At. Spectrom., 2004, 19, 950.

    Article  CAS  Google Scholar 

  11. Y. Ogra, K. Ishiwata, H. Takayama, N. Aimi, and K. T. Suzuki, J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2002, 767, 301.

    Article  CAS  Google Scholar 

  12. Y. Kobayashi, Y. Ogra, K. Ishiwata, H. Takayama, N. Aimi, and K. T. Suzuki, Proc. Natl. Acad. Sci. U. S. A., 2002, 99, 15932.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. M. Kotrebai, J. F. Tyson, E. Block, and P. C. Uden, J. Chromatogr. A, 2000, 866, 51.

    Article  CAS  PubMed  Google Scholar 

  14. M. Montes-Bayon, E. G. Yanes, C. Ponce de Leon, K. Jayasimhulu, A. Stalcup, J. Shann, and J. A. Caruso, Anal. Chem., 2002, 74, 107.

    Article  CAS  PubMed  Google Scholar 

  15. I. Arnault and J. Auger, J. Chromatogr. A, 2006, 1112, 23.

    Article  CAS  PubMed  Google Scholar 

  16. H. Chassaigne, V. Vacchina, and R. Lobinski, TrAC, Trends Anal. Chem., 2000, 19, 300.

    Article  CAS  Google Scholar 

  17. Y. Ogra, T. Kitaguchi, K. Ishiwata, N. Suzuki, Y. Iwashita, and K. T. Suzuki, J. Anal. At. Spectrom., 2007, 22, 1390.

    Article  CAS  Google Scholar 

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Acknowledgments

This study was supported by JSPS KAKENHI Grants (Nos. 25870739 to Y. A. and 26293030 to Y. O.) and the MEXTSupported Program for Strategic Research Foundation at Private Universities (2013-2017). We also thank Takeda Science Foundation, Japan for financial support.

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Authors and Affiliations

  1. Laboratory of Chemical Toxicology and Environmental Health, Showa Pharmaceutical University, Machida, Tokyo, 194-8543, Japan

    Yasumi Anan, Genki Nakajima & Yasumitsu Ogra

  2. Department of Toxicology and Environmental Health, Graduate School of Pharmaceutical Sciences, Chiba University, Chuo, Chiba, 260-8675, Japan

    Yasumitsu Ogra

Authors
  1. Yasumi Anan
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  2. Genki Nakajima
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  3. Yasumitsu Ogra
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Correspondence to Yasumitsu Ogra.

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Anan, Y., Nakajima, G. & Ogra, Y. Complementary Use of LC-ICP-MS and LC-ESI-Q-TOF-MS for Selenium Speciation. ANAL. SCI. 31, 561–564 (2015). https://doi.org/10.2116/analsci.31.561

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  • DOI: https://doi.org/10.2116/analsci.31.561

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