1 Introduction

The theory of time scales (closed subsets of ℝ) was created by Hilger [1] in order to unify continuous and discrete analysis and in order to extend those theories to other kinds of the so-called dynamic equations. Many authors have expounded on various aspects of the theory of dynamic equations on time scales. We refer the reader to the monograph [2] and the references cited therein. Also, a few papers studied the theory of dynamic inequalities on time scales; see, for example, [317].

Differential equations with ‘maxima’ are a special type of differential equations that contain the maximum of the unknown function over a previous interval. Several integral inequalities have been established in the case when maxima of the unknown scalar function is involved in the integral; see [1821] and the references cited therein.

Recently in [22] we initiated the study of integral inequalities on time scales with ‘maxima’, where some new integral inequalities were established. The significance of our work in [22] lies in the fact that ‘maxima’ are taken on intervals [βt,t] which have non-constant length, where 0<β<1. Most papers take the ‘maxima’ on [th,t], where h>0 is a given constant.

In this paper we continue the study of [22] and investigate some nonlinear dynamic integral inequalities on time scales with ‘maxima’. This paper is organized as follows. In Section 2 we give some preliminary results with respect to the calculus on time scales. In Section 3 we deal with our nonlinear dynamic inequalities on time scales with ‘maxima’. In Section 4 we give an example to illustrate our main results.

2 Preliminaries

In this section, we list the following well-known definitions and some lemmas which can be found in [2] and the references therein.

Definition 2.1 A time scale is an arbitrary nonempty closed subset of the real set ℝ with the topology and ordering inherited from ℝ.

The forward and backward jump operators σ,ρ:TT and the graininess μ:T R + are defined, respectively, by

σ(t):=inf{sT|s>t},ρ(t):=sup{sT|s<t},μ(t):=σ(t)t

for all tT. If σ(t)>t, t is said to be right scattered, and if ρ(t)<t, t is said to be left scattered; if σ(t)=t, t is said to be right dense, and if ρ(t)=t, t is said to be left dense. If has a right-scattered minimum m, define T k =T{m}; otherwise set T k =T. If has a left-scattered maximum M, define T k =T{M}; otherwise set T k =T.

Definition 2.2 A function f:TR is rd-continuous (rd-continuous is short for right-dense continuous) provided it is continuous at each right-dense point in and has a left-sided limit at each left-dense point in . The set of rd-continuous functions f:TR will be denoted by C rd (T)= C rd (T,R).

Definition 2.3 For f:TR and t T k , the delta derivative of f at the point t is defined to be the number f (t) (provided it exists) with the property that for each ε>0, there is a neighborhood U of t such that

|f ( σ ( t ) ) f(s) f (t) ( σ ( t ) s ) |ε|σ(t)s|

for all sU.

Definition 2.4 For a function f:TR (the range ℝ of f may be actually replaced by a Banach space), the (delta) derivative is defined at point t by

f (t)= f ( σ ( t ) ) f ( t ) σ ( t ) t ,

if f is continuous at t and t is right scattered. If t is not right scattered, then the derivative is defined by

f (t)= lim s t f ( σ ( t ) ) f ( s ) σ ( t ) s = lim s t f ( t ) f ( s ) t s ,

provided this limit exists.

Definition 2.5 If F (t)=f(t), then we define the delta integral by

a t f(s)Δs=F(t)F(a).

Lemma 2.1 ([2])

Assume that ν:TR is strictly increasing and T ˜ :=ν(T) is a time scale. If f:TR is an rd-continuous function and ν is differentiable with rd-continuous derivative, then for a,bT,

a b f(t) ν (t)Δt= ν ( a ) ν ( b ) ( f ν 1 ) (s) Δ ˜ s.

Lemma 2.2 ([23])

Assume that a0, pq0, and p0. Then

a q p ( q p k q p p a + p q p k q p ) for any k>0.

3 Main results

For convenience of notation, we let throughout t 0 T, t 0 0, T 0 =[ t 0 ,)T and an interval [ γ , η ] T =[γ,η]T. In addition, for a strictly increasing function α:TR, T ˜ =α(T) is a time scale such that T ˜ T. For f C rd (T,R), we define a notation of the composition of two functions on time scales by

f(γ) α 1 (s)=f ( α 1 ( s ) ) ,γT,s T ˜ .

Example 3.1 Let f(t)= 5 t 2 for tT: N 0 1 2 ={ n :n N 0 } and α(t)= t 2 for tT. Then we have α 1 (t)= t for t T ˜ = N 0 and

f(γ) α 1 (s)= ( 5 γ 2 ) s = 5 s ,s T ˜ .

Theorem 3.1 Let the following conditions be satisfied:

  1. (i)

    The function α C rd ( T 0 , R + ) is strictly increasing.

  2. (ii)

    The functions a, b, p and q C rd ( T 0 , R + ).

  3. (iii)

    The function ϕ C rd ( [ β τ , t 0 ] T , R + ), where 0<β<1 and τ=min{ t 0 ,α( t 0 )}.

  4. (iv)

    The function hC( R + ,(0,)) is increasing.

  5. (v)

    The function u C rd ( [ β τ , ) T , R + ) and satisfies the inequalities

    u ( t ) k + t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s u ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] u ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
    (3.1)
u(t)ϕ(t),t [ β τ , t 0 ] T ,
(3.2)

where k0.

Then, for all t T 0 satisfying

H(M)+ t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] ΔsDom ( H 1 ) ,

we have

u(t) H 1 ( H ( M ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,
(3.3)

where

M=max { k , max s [ β τ , t 0 ] T ϕ ( s ) }
(3.4)

and

H(x)= x 0 x 1 h ( r ) dr, x 0 >0,
(3.5)

which H()=, and H 1 is the inverse of H.

Proof We define a function z: [ β τ , ) T R + by

z(t)= { M + t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] α 1 ( s ) Δ ˜ s , t T 0 , M , t [ β τ , t 0 ] T ,

where M is defined by (3.4). Note that the function z(t) is nondecreasing.

It follows that the inequality

u(t)z(t),t [ β τ , ) T

holds. Therefore, for t T 0 and s [ t 0 , t ] T , we have

max ξ [ β s , s ] T u(ξ) max ξ [ β s , s ] T z(ξ)=z(s).

For t T 0 and s [ α ( t 0 ) , α ( t ) ] T ˜ , we have

h ( max ξ [ β γ , γ ] T u ( ξ ) ) α 1 ( s ) h ( max ξ [ β γ , γ ] T z ( ξ ) ) α 1 ( s ) = h ( max ξ [ β α 1 ( s ) , α 1 ( s ) ] T z ( ξ ) ) = h ( z ( α 1 ( s ) ) ) = h ( z ( γ ) ) α 1 ( s ) .

Then, from the definition of z(t) and the above analysis, we get for t T 0 that

z ( t ) M + t 0 t [ p ( s ) h ( z ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T z ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( z ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T z ( ξ ) ) ] α 1 ( s ) Δ ˜ s M + t 0 t [ p ( s ) h ( z ( s ) ) + q ( s ) h ( z ( s ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( z ( γ ) ) + b ( γ ) h ( z ( γ ) ) ] α 1 ( s ) Δ ˜ s = M + t 0 t [ p ( s ) h ( z ( s ) ) + q ( s ) h ( z ( s ) ) ] Δ s + t 0 t [ a ( s ) h ( z ( s ) ) + b ( s ) h ( z ( s ) ) ] α ( s ) Δ s = M + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] h ( z ( s ) ) Δ s .
(3.6)

From inequality (3.6) we have

z (t) [ p ( t ) + q ( t ) + a ( t ) α ( t ) + b ( t ) α ( t ) ] h ( z ( t ) ) ,

which implies

z ( t ) h ( z ( t ) ) p(t)+q(t)+a(t) α (t)+b(t) α (t).
(3.7)

On the other hand, for t T 0 , if σ(t)>t, then

[ H ( z ( t ) ) ] = H ( z ( σ ( t ) ) ) H ( z ( t ) ) σ ( t ) t = 1 σ ( t ) t z ( t ) z ( σ ( t ) ) 1 h ( r ) d r z ( σ ( t ) ) z ( t ) σ ( t ) t 1 h ( z ( t ) ) = z ( t ) h ( z ( t ) ) .
(3.8)

If σ(t)=t, then

[ H ( z ( t ) ) ] = lim s t H ( z ( t ) ) H ( z ( s ) ) t s = lim s t 1 t s z ( s ) z ( t ) 1 h ( r ) d s = lim s t z ( t ) z ( s ) t s 1 h ( ω ) = z ( t ) h ( z ( t ) ) ,
(3.9)

where ω lies between z(s) and z(t). Hence from (3.8) and (3.9) we have

[ H ( z ( t ) ) ] z ( t ) h ( z ( t ) ) .
(3.10)

Combining (3.7) and (3.10), we get

[ H ( z ( t ) ) ] p(t)+q(t)+a(t) α (t)+b(t) α (t).

An integration for the above inequality with respect to t from t 0 to t yields

H ( z ( t ) ) H(M)+ t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δs.

Since H 1 is an increasing function, we obtain

z(t) H 1 ( H ( M ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,t T 0 ,

which results in (3.3). This completes the proof. □

We introduce the following classes of functions in connection with the nonlinearity of the considered integral inequality.

Definition 3.1 ([24])

We will say that a function hC( R + , R + ) is from class Φ if the following conditions are satisfied:

  1. (i)

    h is a nondecreasing function;

  2. (ii)

    h(x)>0 for x>0;

  3. (iii)

    h(tx)th(x) for 0t1, x0;

  4. (iv)

    1 d x h ( x ) =.

Definition 3.2 ([24])

We will say that a function hC( R + , R + ) is from class Ω if the following conditions are satisfied:

  1. (i)

    h is a nondecreasing function;

  2. (ii)

    h(x)>0 for x>0;

  3. (iii)

    h(tx)th(x) for 0t1, x0;

  4. (iv)

    h(x+y)h(x)+h(y) for x,y0;

  5. (v)

    1 d x h ( x ) =.

Note that the functions h(x)= x and h(x)=x are from class Ω.

In the case when in place of the constant k involved in Theorem 3.1 we have a function k(t), we obtain the following result using functions from class Φ.

Theorem 3.2 Let the following conditions be satisfied:

  1. (i)

    The conditions (i)-(iii) of Theorem  3.1 are satisfied.

  2. (ii)

    The function hC( R + , R + ) and hΦ.

  3. (iii)

    The function k C rd ( T 0 ,[1,)) is nondecreasing.

  4. (iv)

    The function u C rd ( [ β τ , ) T , R + ) and satisfies the inequalities

    u ( t ) k ( t ) + t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s u ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] u ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
    (3.11)
    u(t)ϕ(t),t [ β τ , t 0 ] T .
    (3.12)

Then, for all t T 0 satisfying

H(N)+ t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] ΔsDom ( H 1 ) ,

we have

u(t)k(t) H 1 ( H ( N ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,
(3.13)

where

N=max { 1 , max s [ β τ , t 0 ] T ϕ ( s ) k ( t 0 ) } ,
(3.14)

and H(x) is defined by (3.5).

Proof From inequality (3.11) we obtain for t T 0

u ( t ) k ( t ) 1 + t 0 t [ p ( s ) h ( u ( s ) ) k ( t ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) k ( t ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) k ( t ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) k ( t ) ] α 1 ( s ) Δ ˜ s .
(3.15)

Let us define functions k : [ β τ , ) T R + and w: [ β τ , ) T R + by

k ( t ) = { k ( t ) , t T 0 , k ( t 0 ) , t [ β τ , t 0 ] T , w ( t ) = u ( t ) k ( t ) , t [ β τ , ) T .

Note that the function k (t) is nondecreasing on t [ β τ , ) T .

By conditions (ii) and (iii) of Theorem 3.2, it follows that h ( u ( s ) ) k ( t ) h( u ( s ) k ( t ) ) for t T 0 and s [ t 0 , t ] T . From the monotonicity of k(t) and α(t), we get for t T 0 and s [ t 0 , t ] T that

max ξ [ β s , s ] T u ( ξ ) k ( t ) max ξ [ β s , s ] T u ( ξ ) k ( s ) = max ξ [ β s , s ] T u ( ξ ) k ( s ) max ξ [ β s , s ] T u ( ξ ) k ( ξ ) .
(3.16)

For t T 0 and s [ α ( t 0 ) , α ( t ) ] T ˜ , we have

max ξ [ β γ , γ ] T u ( ξ ) α 1 ( s ) k ( t ) = max ξ [ β α 1 ( s ) , α 1 ( s ) ] T u ( ξ ) k ( t ) max ξ [ β α 1 ( s ) , α 1 ( s ) ] T u ( ξ ) k ( α 1 ( s ) ) = max ξ [ β α 1 ( s ) , α 1 ( s ) ] T u ( ξ ) k ( α 1 ( s ) ) max ξ [ β α 1 ( s ) , α 1 ( s ) ] T u ( ξ ) k ( ξ ) = max ξ [ β γ , γ ] T u ( ξ ) k ( ξ ) α 1 ( s ) .
(3.17)

From inequalities (3.15), (3.16) and (3.17) and the definition of w(t), we have

w ( t ) 1 + t 0 t [ p ( s ) h ( w ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T w ( ξ ) ) ] Δ s w ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( w ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T w ( ξ ) ) ] w ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
(3.18)
w(t) ϕ ( t ) k ( t 0 ) ,t [ β τ , t 0 ] T .
(3.19)

Using Theorem 3.1 for (3.18) and (3.19), we get

w(t) H 1 ( H ( N ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,t T 0 ,

which results in (3.13). This completes the proof. □

In the case when the function k(t) involved in the right part of inequality (3.11) is not a monotonic function, we obtain the following result.

Theorem 3.3 Let the following conditions be satisfied:

  1. (i)

    The conditions (i)-(ii) of Theorem  3.1 are satisfied.

  2. (ii)

    The function ϕ C rd ( [ β τ , ) T , R + ) with max s [ β τ , t 0 ] T ϕ(s)>0, where 0<β<1 and τ=min{ t 0 ,α( t 0 )}.

  3. (iii)

    The function hC( R + , R + ) and hΩ.

  4. (iv)

    The function u C rd ( [ β τ , ) T , R + ) and satisfies the inequalities

    u ( t ) ϕ ( t ) + t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s u ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] u ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
    (3.20)
    u(t)ϕ(t),t [ β τ , t 0 ] T .
    (3.21)

Then, for all t T 0 satisfying

H(1)+ t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] ΔsDom ( H 1 ) ,

we have

u(t)ϕ(t)+f(t) H 1 ( H ( 1 ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,
(3.22)

where H(x) is defined by (3.5) and

f ( t ) = max s [ β τ , t 0 ] T ϕ ( s ) + t 0 t [ p ( s ) h ( ϕ ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T ϕ ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( ϕ ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T ϕ ( ξ ) ) ] α 1 ( s ) Δ ˜ s , t T 0 .
(3.23)

Proof Let us define a function z: [ β τ , ) T R + by

z(t)={ t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] α 1 ( s ) Δ ˜ s , t T 0 , 0 , t [ β τ , t 0 ] T .
(3.24)

Therefore,

u(t)ϕ(t)+z(t),t [ β τ , ) T .
(3.25)

From the definition of the function z(t), it follows that

z ( t ) t 0 t { p ( s ) h ( ϕ ( s ) + z ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T ϕ ( ξ ) + max ξ [ β s , s ] T z ( ξ ) ) } Δ s z ( t ) + α ( t 0 ) α ( t ) { a ( γ ) h ( ϕ ( γ ) + z ( γ ) ) z ( t ) + b ( γ ) h ( max ξ [ β γ , γ ] T ϕ ( ξ ) + max ξ [ β γ , γ ] T z ( ξ ) ) } α 1 ( s ) Δ ˜ s z ( t ) f ( t ) + t 0 t { p ( s ) h ( z ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T z ( ξ ) ) } Δ s z ( t ) + α ( t 0 ) α ( t ) { a ( γ ) h ( z ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T z ( ξ ) ) } α 1 ( s ) Δ ˜ s , t T 0 ,
(3.26)
z(t)ϕ(t),t [ β τ , t 0 ] T ,
(3.27)

where the function f(t) is defined in (3.23).

Since the function f(t): T 0 (0,) is nondecreasing and f( t 0 )= max s [ β τ , t 0 ] T ϕ(s), by using Theorem 3.2 for (3.26) and (3.27), we get

z(t)f(t) H 1 ( H ( 1 ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,t T 0 ,

which results in (3.22). This completes the proof. □

Now we will consider an inequality in which the unknown function into the left part is presented in a power.

Theorem 3.4 Let the following conditions be fulfilled:

  1. (i)

    The conditions (i)-(iii) of Theorem  3.1 and (iii) of Theorem  3.3 are satisfied.

  2. (ii)

    The function k C rd ( T 0 ,(0,)) is nondecreasing and the following inequality

    L:= max s [ β τ , t 0 ] T ϕ(s) k ( t 0 ) n ,n>1
    (3.28)

holds.

  1. (iii)

    The function u C rd ( [ β τ , ) T , R + ) and satisfies the inequalities

    u n ( t ) k ( t ) + t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s u n ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] u n ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
    (3.29)
    u(t)ϕ(t),t [ β τ , t 0 ] T .
    (3.30)

Then, for all t T 0 satisfying

H(1)+ t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] ΔsDom ( H 1 ) ,

we have

u ( t ) 1 n c 1 n n k ( t ) + n 1 n c 1 n + ( L + g ( t ) ) H 1 ( H ( 1 ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,
(3.31)

where

g ( t ) = t 0 t [ p ( s ) h ( w ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T w ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( w ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T w ( ξ ) ) ] α 1 ( s ) Δ ˜ s ,
(3.32)

with

w(t)={ 1 n c 1 n n k ( t ) + n 1 n c 1 n , t T 0 , 1 n c 1 n n k ( t 0 ) + n 1 n c 1 n , t [ β τ , t 0 ] T
(3.33)

for any constant c1.

Proof Define a function z: [ β τ , ) T R + by

z(t)={ t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] α 1 ( s ) Δ ˜ s , t T 0 , 0 , t [ β τ , t 0 ] T .
(3.34)

It follows from inequality (3.29) for t T 0 that

u(t) [ k ( t ) + z ( t ) ] 1 n .

Using Lemma 2.2, for any c1, we obtain

u ( t ) 1 n c 1 n n [ k ( t ) + z ( t ) ] + n 1 n c 1 n = 1 n c 1 n n k ( t ) + n 1 n c 1 n + 1 n c 1 n n z ( t ) = w ( t ) + 1 n c 1 n n z ( t ) , t T 0 .
(3.35)

From inequality (3.28) and applying Lemma 2.2, for any c1, we have

k ( t 0 ) n 1 n c 1 n n k( t 0 )+ n 1 n c 1 n .
(3.36)

Indeed, by using inequality (3.36), we have for t [ β τ , t 0 ] T

u(t)ϕ(t)ϕ(t)+ 1 n c 1 n n z(t)w(t)+ 1 n c 1 n n z(t),
(3.37)

where w(t) is defined by (3.33).

Now we define a nondecreasing function v: T 0 (0,) by v(t)=L+g(t), where L and g(t) are defined by (3.28) and (3.32), respectively.

From the definition of the function z(t), it follows that

z ( t ) t 0 t { p ( s ) h ( w ( s ) + 1 n c 1 n n z ( s ) ) z ( t ) + q ( s ) h ( max ξ [ β s , s ] T w ( ξ ) + 1 n c 1 n n max ξ [ β s , s ] T z ( ξ ) ) } Δ s z ( t ) + α ( t 0 ) α ( t ) { a ( γ ) h ( w ( γ ) + 1 n c 1 n n z ( γ ) ) z ( t ) + b ( γ ) h ( max ξ [ β γ , γ ] T w ( ξ ) + 1 n c 1 n n max ξ [ β γ , γ ] T z ( ξ ) ) } α 1 ( s ) Δ ˜ s z ( t ) v ( t ) + t 0 t [ p ( s ) h ( 1 n c 1 n n z ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T 1 n c 1 n n z ( ξ ) ) ] Δ s z ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( 1 n c 1 n n z ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T 1 n c 1 n n z ( ξ ) ) ] z ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
(3.38)
z(t)ϕ(t),t [ β τ , t 0 ] T .
(3.39)

From inequalities (3.38) and (3.39), we get for c1, n>1

1 n c 1 n n z ( t ) v ( t ) + t 0 t [ p ( s ) h ( 1 n c 1 n n z ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T 1 n c 1 n n z ( ξ ) ) ] Δ s 1 n c 1 n n z ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( 1 n c 1 n n z ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T 1 n c 1 n n z ( ξ ) ) ] 1 n c 1 n n z ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
(3.40)
1 n c 1 n n z(t)ϕ(t),t [ β τ , t 0 ] T .
(3.41)

Applying Theorem 3.2 for (3.40) and (3.41), we obtain

1 n c 1 n n z(t)v(t) H 1 ( H ( 1 ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,t T 0 ,

which results in (3.31). This completes the proof. □

Next we will consider an inequality which has powers on both sizes.

Theorem 3.5 Let the following conditions be fulfilled:

  1. (i)

    The conditions (i)-(iii) of Theorem  3.1 and (iii) if Theorem  3.3 are satisfied.

  2. (ii)

    The function k C rd ( T 0 ,(0,)) is nondecreasing and the following inequality

    K:= max s [ β τ , t 0 ] T { ϕ ε ( s ) , ϕ l ( s ) } m n c m n n k( t 0 )+ n 1 n c m n
    (3.42)

holds for any constant c1 and nmlδε>1.

  1. (iii)

    The function u C rd ( [ β τ , ) T , R + ) and satisfies the inequalities

    u n ( t ) k ( t ) + t 0 t [ p ( s ) h ( u m ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u l ( ξ ) ) ] Δ s u n ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( u δ ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ε ( ξ ) ) ] u n ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
    (3.43)
    u(t)ϕ(t),t [ β τ , t 0 ] T .
    (3.44)

Then, for all t T 0 satisfying

H(1)+ t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] ΔsDom ( H 1 ) ,

we have

u ( t ) 1 n c 1 n n k ( t ) + n 1 n c 1 n + 1 m c 1 m n ( K + λ ( t ) ) H 1 ( H ( 1 ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,
(3.45)

where

λ ( t ) = t 0 t [ p ( s ) h ( w ¯ ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T w ¯ ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( w ¯ ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T w ¯ ( ξ ) ) ] α 1 ( s ) Δ ˜ s ,
(3.46)

with

w ¯ (t)={ m n c m n n k ( t ) + n 1 n c m n , t T 0 , m n c m n n k ( t 0 ) + n 1 n c m n , t [ β τ , t 0 ] T .
(3.47)

Proof We define a function z: [ β τ , ) T R + by

z(t)={ t 0 t [ p ( s ) h ( u m ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u l ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( u δ ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ε ( ξ ) ) ] α 1 ( s ) Δ ˜ s , t T 0 , 0 , t [ β τ , t 0 ] T .
(3.48)

From inequality (3.43) we have for t T 0

u ( t ) [ k ( t ) + z ( t ) ] 1 n , u l ( t ) [ k ( t ) + z ( t ) ] l n , u m ( t ) [ k ( t ) + z ( t ) ] m n , u δ ( t ) [ k ( t ) + z ( t ) ] δ n , u ε ( t ) [ k ( t ) + z ( t ) ] ε n .

By using Lemma 2.2, for any c1, we obtain

u(t) 1 n c 1 n n k(t)+ n 1 n c 1 n + 1 n c 1 n n z(t),t T 0 ,
(3.49)
u ε ( t ) ε n c ε n n k ( t ) + n ε n c ε n + ε n c ε n n z ( t ) u ε ( t ) w ¯ ( t ) + m n c m n n z ( t ) , t T 0 ,
(3.50)
u δ ( t ) δ n c δ n n k ( t ) + n δ n c δ n + δ n c δ n n z ( t ) u δ ( t ) w ¯ ( t ) + m n c m n n z ( t ) , t T 0 ,
(3.51)
u l ( t ) l n c l n n k ( t ) + n l n c l n + l n c l n n z ( t ) u l ( t ) w ¯ ( t ) + m n c m n n z ( t ) , t T 0 ,
(3.52)
u m ( t ) m n c m n n k ( t ) + n m n c m n + m n c m n n z ( t ) u m ( t ) w ¯ ( t ) + m n c m n n z ( t ) , t T 0 .
(3.53)

Moreover, we have

u ε ( t ) ϕ ε ( t ) ϕ ε ( t ) + m n c m n n z ( t ) w ¯ ( t ) + m n c m n n z ( t ) , t [ β τ , t 0 ] T
(3.54)

and

u l ( t ) ϕ l ( t ) ϕ l ( t ) + m n c m n n z ( t ) w ¯ ( t ) + m n c m n n z ( t ) , t [ β τ , t 0 ] T ,
(3.55)

where w ¯ (t) is defined by (3.47). From the definition of the function z(t), it follows that

z ( t ) t 0 t { p ( s ) h ( w ¯ ( s ) + m n c m n n z ( s ) ) z ( t ) + q ( s ) h ( max ξ [ β s , s ] T w ¯ ( ξ ) + max ξ [ β s , s ] T m n c m n n z ( ξ ) ) } Δ s z ( t ) + α ( t 0 ) α ( t ) { a ( γ ) h ( w ¯ ( γ ) + m n c m n n z ( γ ) ) z ( t ) + b ( γ ) h ( max ξ [ β γ , γ ] T w ¯ ( ξ ) + max ξ [ β γ , γ ] T m n c m n n z ( ξ ) ) } α 1 ( s ) Δ ˜ s z ( t ) ρ ( t ) + t 0 t [ p ( s ) h ( m n c m n n z ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T m n c m n n z ( ξ ) ) ] Δ s z ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( m n c m n n z ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T m n c m n n z ( ξ ) ) ] z ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
(3.56)
z(t)ϕ(t),t [ β τ , t 0 ] T .
(3.57)

From inequalities (3.56) and (3.57), we have

m n c m n n z ( t ) ρ ( t ) + t 0 t [ p ( s ) h ( m n c m n n z ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T m n c m n n z ( ξ ) ) ] Δ s m n c m n n z ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( m n c m n n z ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T m n c m n n z ( ξ ) ) ] m n c m n n z ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
(3.58)
m n c m n n z(t)ϕ(t),t [ β τ , t 0 ] T ,
(3.59)

where a nondecreasing function ρ(t): T 0 (0,) is defined by ρ(t):=K+λ(t), where K and λ(t) are defined in (3.42) and (3.46), respectively.

Applying Theorem 3.2 for (3.58) and (3.59), we obtain

m n c m n n z(t)ρ(t) H 1 ( H ( 1 ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,t T 0 ,

which results in (3.45). This completes the proof. □

In the case when the unknown function is involved nonlinearly in the left part of the inequality, we obtain the following result.

Theorem 3.6 Let the following conditions be fulfilled:

  1. (i)

    The conditions (i)-(iv) of Theorem  3.1 are satisfied.

  2. (ii)

    The function ΨC( R + , R + ) is strictly increasing, lim t Ψ(t)=.

  3. (iii)

    The function u C rd ( [ β τ , ) T , R + ) and satisfies the inequalities

    Ψ ( u ( t ) ) k + t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s Ψ ( u ( t ) ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] Ψ ( u ( t ) ) α 1 ( s ) Δ ˜ s , t T 0 ,
    (3.60)
u(t)ϕ(t),t [ β τ , t 0 ] T ,
(3.61)

where k0.

Then, for all t T 0 satisfying

H ˜ ( Ψ ( P ) ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] ΔsDom ( H ˜ 1 )

and

H ˜ 1 ( H ˜ ( Ψ ( P ) ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) Dom ( Ψ 1 ) ,

we have

u(t) Ψ 1 { H ˜ 1 ( H ˜ ( Ψ ( P ) ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) } ,
(3.62)

where

P=max { Ψ 1 ( k ) , max s [ β τ , t 0 ] T ϕ ( s ) }
(3.63)

and

H ˜ (x)= x 0 x 1 h ( Ψ 1 ( r ) ) dr, x 0 >0,
(3.64)

where H ˜ ()=, and H ˜ 1 is the inverse of H ˜ .

Proof Define a function z: [ β τ , ) T R + by

z(t)= { Ψ ( P ) + t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] α 1 ( s ) Δ ˜ s , t T 0 , Ψ ( P ) , t [ β τ , t 0 ] T ,

where P is defined by (3.63). Note that the function z(t) is nondecreasing.

It follows that the inequality

u(t) Ψ 1 ( z ( t ) ) ,t [ β τ , ) T

holds. Therefore, for t T 0 and s [ t 0 , t ] T , we have

max ξ [ β s , s ] T u(ξ) max ξ [ β s , s ] T Ψ 1 ( z ( ξ ) ) = Ψ 1 ( z ( s ) ) .

For t T 0 and s [ α ( t 0 ) , α ( t ) ] T ˜ , we have

h ( max ξ [ β γ , γ ] T u ( ξ ) ) α 1 ( s ) h ( max ξ [ β γ , γ ] T Ψ 1 ( z ( ξ ) ) ) α 1 ( s ) = h ( max ξ [ β α 1 ( s ) , α 1 ( s ) ] T Ψ 1 ( z ( ξ ) ) ) = h ( Ψ 1 ( z ( α 1 ( s ) ) ) ) = h ( Ψ 1 ( z ( γ ) ) ) α 1 ( s ) .

Then, from the definition of z(t) and the above analysis, we get for t T 0 that

z ( t ) Ψ ( P ) + t 0 t [ p ( s ) h ( Ψ 1 ( z ( s ) ) ) + q ( s ) h ( max ξ [ β s , s ] T Ψ 1 ( z ( ξ ) ) ) ] Δ s z ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( Ψ 1 ( z ( γ ) ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T Ψ 1 ( z ( ξ ) ) ) ] z ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
(3.65)
z(t)Ψ(P),t [ β τ , t 0 ] T .
(3.66)

According to Theorem 3.1, from inequalities (3.65) and (3.66), we have

z(t) H ˜ 1 ( H ˜ ( Ψ ( P ) ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,t T 0 ,

which results in (3.62). This completes the proof. □

In the case when in place of the constant k involved in Theorem 3.6 we have a function k(t), we obtain the following result.

Theorem 3.7 Let the following conditions be fulfilled:

  1. (i)

    The conditions (i)-(iii) of Theorem  3.1, (ii) of Theorem  3.2 and (ii) of Theorem  3.6 are satisfied.

  2. (ii)

    The function k C rd ( T 0 ,[1,)) is nondecreasing and the inequality Q= max s [ β τ , t 0 ] T ϕ(s) Ψ 1 (k( t 0 )) holds.

  3. (iii)

    The function u C rd ( [ β τ , ) T , R + ) and satisfies the inequalities

    Ψ ( u ( t ) ) k ( t ) + t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s Ψ ( u ( t ) ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] Ψ ( u ( t ) ) α 1 ( s ) Δ ˜ s , t T 0 ,
    (3.67)
    u(t)ϕ(t),t [ β τ , t 0 ] T .
    (3.68)

Then, for all t T 0 satisfying

H ˜ (1)+ t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] ΔsDom ( H ˜ 1 )

and

k(t) H ˜ 1 ( H ˜ ( 1 ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) Dom ( Ψ 1 ) ,

we have

u(t) Ψ 1 { k ( t ) H ˜ 1 ( H ˜ ( 1 ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) } ,
(3.69)

where H ˜ (x) is defined by (3.64).

Proof Define a function z: [ β τ , ) T R + by

z(t)= { k ( t ) + t 0 t [ p ( s ) h ( u ( s ) ) + q ( s ) h ( max ξ [ β s , s ] T u ( ξ ) ) ] Δ s + α ( t 0 ) α ( t ) [ a ( γ ) h ( u ( γ ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T u ( ξ ) ) ] α 1 ( s ) Δ ˜ s , t T 0 , k ( t 0 ) , t [ β τ , t 0 ] T .

Note that the function z(t) is nondecreasing. It follows that the inequality

u(t) Ψ 1 ( z ( t ) ) ,t [ β τ , ) T

holds. Therefore, for t T 0 and s [ t 0 , t ] T , we have

max ξ [ β s , s ] T u(ξ) max ξ [ β s , s ] T Ψ 1 ( z ( ξ ) ) = Ψ 1 ( z ( s ) ) .

For t T 0 and s [ α ( t 0 ) , α ( t ) ] T ˜ , we have

h ( max ξ [ β γ , γ ] T u ( ξ ) ) α 1 ( s ) h ( max ξ [ β γ , γ ] T Ψ 1 ( z ( ξ ) ) ) α 1 ( s ) = h ( max ξ [ β α 1 ( s ) , α 1 ( s ) ] T Ψ 1 ( z ( ξ ) ) ) = h ( Ψ 1 ( z ( α 1 ( s ) ) ) ) = h ( Ψ 1 ( z ( γ ) ) ) α 1 ( s ) .

Then, from the definition of z(t) and the above analysis, we get for t T 0 that

z ( t ) k ( t ) + t 0 t [ p ( s ) h ( Ψ 1 ( z ( s ) ) ) + q ( s ) h ( max ξ [ β s , s ] T Ψ 1 ( z ( ξ ) ) ) ] Δ s z ( t ) + α ( t 0 ) α ( t ) [ a ( γ ) h ( Ψ 1 ( z ( γ ) ) ) + b ( γ ) h ( max ξ [ β γ , γ ] T Ψ 1 ( z ( ξ ) ) ) ] z ( t ) α 1 ( s ) Δ ˜ s , t T 0 ,
(3.70)
z(t)k( t 0 ),t [ β τ , t 0 ] T .
(3.71)

According to Theorem 3.2, from inequalities (3.70) and (3.71), we have

z(t)k(t) H ˜ 1 ( H ˜ ( 1 ) + t 0 t [ p ( s ) + q ( s ) + a ( s ) α ( s ) + b ( s ) α ( s ) ] Δ s ) ,t T 0 ,

which results in (3.69). This completes the proof. □

4 An application

In this section, in order to illustrate our results, we consider the following first-order dynamic equation with ‘maxima’:

x (t)=F ( t , x ( t ) , max s [ β t , t ] T x ( s ) ) ,t T 0 ,
(4.1)

and initial condition

x(t)=ϕ(t),t [ β τ , t 0 ] T ,
(4.2)

where F C rd ( T 0 ×R×R,R), ϕ C rd ( [ β t 0 , t 0 ] T ,R), 0<β<1, τ is a constant such that βτ t 0 .

Corollary 4.1 Assume that:

(H1) There exists a strictly increasing function α C rd ( T 0 , R + ) such that α(T)= T ˜ is a time scale and min{ t 0 ,α( t 0 )}=τ.

(H2) There exist functions A,B,C,D, α C rd ( T 0 , R + ) and an integer p>1 such that for t T 0 , u,vR,

|F(t,u,v)| ( A ( t ) + B ( t ) α ( t ) ) | u | p + ( C ( t ) + D ( t ) α ( t ) ) | v | p .
(4.3)

Then the solution x(t) of IVP (4.1)-(4.2) satisfies the following inequality:

|x(t)| { M p 1 p + p 1 p t 0 t [ A ( s ) + C ( s ) + B ( s ) α ( s ) + D ( s ) α ( s ) ] Δ s } p p 1 ,t T 0 ,
(4.4)

where

M= max s [ β τ , t 0 ] T |ϕ(s)|.

Proof It is easy to see that the solution x(t) of IVP (4.1)-(4.2) satisfies the following equation:

x(t)=ϕ( t 0 )+ t 0 t F ( s , x ( s ) , max ξ [ β s , s ] T x ( ξ ) ) Δs.
(4.5)

Using the assumption (H2), it follows from (4.5) that

| x ( t ) | | ϕ ( t 0 ) | + t 0 t | F ( s , x ( s ) , max ξ [ β s , s ] T x ( ξ ) ) | Δ s | ϕ ( t 0 ) | + t 0 t [ ( A ( s ) + B ( s ) α ( s ) ) | x ( s ) | p + ( C ( s ) + D ( s ) α ( s ) ) | max ξ [ β s , s ] T x ( ξ ) | p ] Δ s | ϕ ( t 0 ) | + t 0 t [ A ( s ) | x ( s ) | p + C ( s ) max ξ [ β s , s ] T | x ( ξ ) | p ] Δ s + t 0 t [ B ( s ) | x ( s ) | p + D ( s ) max ξ [ β s , s ] T | x ( ξ ) | p ] α ( s ) Δ s = | ϕ ( t 0 ) | + t 0 t [ A ( s ) | x ( s ) | p + C ( s ) max ξ [ β s , s ] T | x ( ξ ) | p ] Δ s + α ( t 0 ) α ( t ) [ B ( γ ) | x ( γ ) | p + D ( γ ) max ξ [ β γ , γ ] T | x ( ξ ) | p ] α 1 ( s ) Δ ˜ s .
(4.6)

Hence Corollary 4.1 yields the estimate

|x(t)| { M p 1 p + p 1 p t 0 t [ A ( s ) + C ( s ) + B ( s ) α ( s ) + D ( s ) α ( s ) ] Δ s } p p 1 ,t T 0 .
(4.7)

Inequality (4.7) gives the bound on the solution x(t) of IVP (4.1)-(4.2). □

Example 4.1 Consider the following first-order dynamic equation with ‘maxima’ on time scale T={ 2 n :nZ}{0} (ℤ stands for the integer set):

{ x ( t ) = 1 2 tan 1 ( ( 2 + 8 t 2 ) x ( t ) 3 ) x ( t ) = + 2 sin ( ( e 2 t + 4 cos 2 ( π t ) ) max s [ 1 16 t , t ] T x ( s ) 3 ) , t T 0 , x ( t ) = 3 , t [ 1 8 , 2 ] T ,
(4.8)

where T 0 =[2,)T.

Here ϕ(t)=3, β=1/16, p=3, F(t,x(t), max s [ β t , t ] T x(s))=( tan 1 ((2+8 t 2 )× x ( t ) 3 ))/2+2sin(( e 2 t +4 cos 2 (πt)) max s [ 1 16 t , t ] T x ( s ) 3 ), t 0 =2, τ=2.

By choosing α(t)=4t, we can show that α(T)= T ˜ T and min{ t 0 ,α( t 0 )}=2. Clearly,

| F ( t , x ( t ) , max s [ β t , t ] T x ( s ) ) | = | 1 2 tan 1 ( ( 2 + 8 t 2 ) x ( t ) 3 ) + 2 sin ( ( e 2 t + 4 cos 2 ( π t ) ) max s [ 1 16 t , t ] T x ( s ) 3 ) | ( 1 + 4 t 2 ) | x ( t ) | 3 + ( 2 e 2 t + 8 cos 2 ( π t ) ) | max s [ 1 16 t , t ] T x ( s ) | 3

and

max s [ ( 1 / ( 8 ) ) , ( 2 ) ] T |ϕ(s)|=3.

On the other hand, we have α (t)=4. Set A(t)=1, B(t)= t 2 , C(t)=2 e 2 t and D(t)=2 cos 2 (πt). Hence, Corollary 4.1 yields the estimate

|x(t)| { 3 2 3 + 2 3 2 t [ 1 + 2 e 2 s + 4 s 2 + 8 cos 2 ( π s ) ] Δ s } 3 2 ,t T 0 .

Authors’ information

Sotiris K Ntouyas is a member of Nonlinear Analysis and Applied Mathematics (NAAM) Research Group at King Abdulaziz University, Jeddah, Saudi Arabia.