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The Battery of Analytical Techniques Necessary for the Effective Characterization of Solutions of Temperature-Sensitive Polymers

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Abstract

This review aims to highlight the most effective ways of studying temperature-sensitive polymer solutions, which exhibit phase separation phenomena caused by variations in temperature. As a result of phase separation, temperature-sensitive polymer systems can form well-defined self-assembled nanostructures with a number of different practical application such as in drug and gene delivery, tissue engineering, etc. In order to establish the required properties for applications, a rigorous characterization of the phase separation phenomenon is essential. This review describes the application of different spectroscopic and calorimetric methods, including NMR, DLS, SAXS, IR, Raman spectroscopy and DSC, for this purpose.

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Funding

This work was supported by World Premier International Research Center Initiative (WPI Initiative) from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan.

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Authors and Affiliations

  1. Institute of Macromolecular Chemistry, AS CR, 162 06, Prague, Czech Republic

    Nadiia Velychkivska & Larisa Janisova

  2. Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, 128 40, Prague, Czech Republic

    Nadiia Velychkivska

  3. International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), 305-0044, Tsukuba, Ibaraki, Japan

    Jonathan P. Hill & Jan Labuta

Authors
  1. Nadiia Velychkivska
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  2. Larisa Janisova
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Correspondence to Nadiia Velychkivska or Larisa Janisova.

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Velychkivska, N., Janisova, L., Hill, J.P. et al. The Battery of Analytical Techniques Necessary for the Effective Characterization of Solutions of Temperature-Sensitive Polymers. rev. and adv. in chem. 11, 100–111 (2021). https://doi.org/10.1134/S2079978021010076

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  • DOI: https://doi.org/10.1134/S2079978021010076

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