Abstract
Contemporary cell investigation methods permit us to describe the molecular transport mechanisms of intracellular substances and cell components. Analysis of the completeness and the consistency of the existing transport network data and their utilization is an issue for mathematical modeling. Self-organization of the cell transport network and transport of the cargo and organelles upon it are modeled in this work by examples of the mitotic spindle formation, retrograde axonal transport, and lipid transport.
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Original Russian Text © K.A. Novikov, A.A. Romanyukha, A.N. Gratchev, J.G. Kzhyshkowska, O.A. Melnichenko, 2015, published in Matematicheskoe Modelirovanie, 2015, Vol. 27, No. 3, pp. 49–62.
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Novikov, K.A., Romanyukha, A.A., Gratchev, A.N. et al. Mathematical model of cellular transport network self-organization and functioning. Math Models Comput Simul 7, 475–484 (2015). https://doi.org/10.1134/S2070048215050099
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DOI: https://doi.org/10.1134/S2070048215050099