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Signal molecules during the organism development: Central and peripheral sources of noradrenaline in rat ontogenesis

  • Biochemistry, Biophysics and Molecular Biology
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Abstract

Using the method of high performance liquid chromatography with electrochemical detection, the age dynamics of the content of noradrenaline (NA) in the brain, adrenal gland, and the organ of Zuckerkandl in prenatal (18th and 21st days of embryogenesis) and early postnatal (3, 7, 15, and 30th days) periods of development was studied. The potential contribution of these organs to the formation of physiologically active concentration of noradrenalin in the blood was also assessed. The results suggest that, during the development of the organism, the activity of the sources of noradrenaline in the general circulation changes, which gives a reason to assume the existence of humoral interaction between NA-producing organs in the perinatal period of ontogenesis.

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References

  1. Lauder, J.M., Trends Neurosci., 1993, vol. 16, pp. 233–240.

    Article  CAS  PubMed  Google Scholar 

  2. Nguyen, L., Rigo, J.M., Rocher, V., Belachew, S., Malgrange, B., Rogister, B., Leprince, P., and Moonen, G., Cell. Tissue Res., 2001, vol. 305, pp. 187–202.

    Article  CAS  PubMed  Google Scholar 

  3. Izvolskaia, M., Duittoz, A.H., Tillet, Y., and Ugrumov, M.V., Brain Struct. Funct., 2009, vol. 213, pp. 289–300.

    Article  CAS  PubMed  Google Scholar 

  4. Kreider, M.L., Seidler, F.J., Cousins, M., Tate, C.A., and Slotkin, T.A., Brain Res. Develop. Brain Res., 2004, vol. 152, pp. 233–239.

    Article  CAS  Google Scholar 

  5. Hildreth, V., Anderson, R.H., and Henderson, D.J., Clin. Anat., 2009, vol. 22, pp. 36–46.

    Article  PubMed  Google Scholar 

  6. Viemari, J.C., Bevengut, M., Burnet, H., Coulon, P., Pequignot, J.M., Tiveron, M.C., and Hilaire, G., J. Neurosci., 2004, vol. 24, pp. 928–937.

    Article  CAS  PubMed  Google Scholar 

  7. Nomura, Y., Naitoh, F., and Segawa, T., Brain Res., 1976, vol. 101, pp. 305–315.

    Article  CAS  PubMed  Google Scholar 

  8. Huber, K., Kalcheim, C., and Unsicker, K., Auton. Neurosci., 2009, vol. 151, pp. 10–16.

    Article  CAS  PubMed  Google Scholar 

  9. Schober, A., Parlato, R., Huber, K., Kinscherf, R., Hartleben, B., Huber, T.B., Schutz, G., and Unsicker, K., J. Neuroendocrinol., 2013, vol. 25, pp. 34–47.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Ugrumov, M.V., Neurochem. Res., 2010, vol. 35, pp. 837–850.

    Article  CAS  PubMed  Google Scholar 

  11. Tomlinson, A. and Coupland, R.E., J. Anat., 1990, vol. 169, pp. 209–236.

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Tishler, A., Toxicolog. Pathol., 1989, vol. 17, pp. 330–332.

    Article  Google Scholar 

  13. Ramiro-Fuentes, S., Marco, A., Galan-Rodriguez, B., Ramirez-Ponce, P., and Fernandez-Espejo, E., Neurobiol. Aging, 2010, vol. 31, pp. 2115–2127.

    Article  CAS  PubMed  Google Scholar 

  14. Zubova, Yu.O., Bondarenko, N.S., Sapronova, A.Ya., and Ugrumov, M.V., Dokl. Biochem. Biophys., 2015, vol. 461, pp. 123–126.

    Article  CAS  PubMed  Google Scholar 

  15. Saifetyarova, Yu.Yu., Melnikova, V.I., Sapronova, A.Ja., and Ugrumov, M.V., Dokl. Biol. Sci., 2014, vol. 454, pp. 5–8.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Koltzov Institute of Developmental Biology, Russian Academy of Sciences, ul. Vavilova 26, Moscow, 119334, Russia

    A. R. Murtazina, Y. O. Nikishina, N. S. Bondarenko, A. Ja. Sapronova & M. V. Ugrumov

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  1. A. R. Murtazina
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  2. Y. O. Nikishina
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  3. N. S. Bondarenko
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  4. A. Ja. Sapronova
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  5. M. V. Ugrumov
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Correspondence to A. R. Murtazina.

Additional information

Original Russian Text © A.R. Murtazina, Y.O. Nikishina, N.S. Bondarenko, A.Ja. Sapronova, M.V. Ugrumov, 2016, published in Doklady Akademii Nauk, 2016, Vol. 466, No. 6, pp. 730–733.

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Murtazina, A.R., Nikishina, Y.O., Bondarenko, N.S. et al. Signal molecules during the organism development: Central and peripheral sources of noradrenaline in rat ontogenesis. Dokl Biochem Biophys 466, 74–76 (2016). https://doi.org/10.1134/S160767291601018X

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  • DOI: https://doi.org/10.1134/S160767291601018X

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