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5,7-Dihydropyrrolo[3,4-d][1,2]diazepin-1(2H)-ones. Synthesis and transformations

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Abstract

A preparative procedure has been developed for the synthesis of substituted 5,7-dihydropyrrolo-[3,4-d][1,2]diazepines by recyclization of 6-phenylpyrano[3,4-c]pyrrol-4(2H)-one with hydrazine hydrate. The stability of the seven-membered ring in the products under acidic conditions, alkylation, and heteroring fusion to the diazepine ring have been studied.

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Authors and Affiliations

  1. Litvinenko Institute of Physical Organic and Coal Chemistry, ul. R. Lyuksemburg 70, Donetsk, 83114, Ukraine

    O. I. Kharaneko

  2. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, ul. Murmanskaya 5, Kiev, 02660, Ukraine

    S. L. Bogza

Authors
  1. O. I. Kharaneko
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  2. S. L. Bogza
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Correspondence to O. I. Kharaneko.

Additional information

Original Russian Text © O.I. Kharaneko, S.L. Bogza, 2016, published in Zhurnal Organicheskoi Khimii, 2016, Vol. 52, No. 7, pp. 1049–1055.

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Kharaneko, O.I., Bogza, S.L. 5,7-Dihydropyrrolo[3,4-d][1,2]diazepin-1(2H)-ones. Synthesis and transformations. Russ J Org Chem 52, 1043–1049 (2016). https://doi.org/10.1134/S1070428016070228

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  • DOI: https://doi.org/10.1134/S1070428016070228

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