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Histological Assessment of the Laboratory Rats Skin after Thermal Damages Treated with Nanosecond Microwave Pulses

  • ANIMAL AND HUMAN PHYSIOLOGY
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Abstract

The effect of nanosecond repetitive pulsed microwaves (RPMs, 10 GHz, 100 ns pulse duration, 8 Hz pulse repetition rate, 140 W/cm2 peak power flux density (pPFD)) on the treatment of a model thermal burn of the skin of laboratory rats was investigated. It is established that after 4-fold local irradiation, the rate of wound healing increases; it is due to the accelerated formation of granulation tissue and a decrease in the thickness of the scab, which ensures scarless healing.

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Authors and Affiliations

  1. Institute of High Current Electronics Siberian Branch, Russian Academy of Sciences, 634055, Tomsk, Russia

    A. A. Gostyukhina, A. V. Samoylova, M. A. Bolshakov, O. P. Kutenkov & V. V. Rostov

  2. Federal Scientific and Clinical Center of Medical Rehabilitation and Balneology of the Federal Medical and Biological Agency of Russia, 141551, Goluboe village, Solnechnogorsk district, Moscow oblast, Russia

    A. A. Gostyukhina, V. V. Yartsev, S. S. Evseeva & K. V. Zaitsev

  3. National Research Tomsk State University, 634050, Tomsk, Russia

    A. A. Gostyukhina, V. V. Yartsev, A. V. Samoylova, M. A. Bolshakov, S. S. Evseeva & V. M. Mochalova

  4. Siberian State Medical University of the Ministry of Health of the Russian Federation, 634050, Tomsk, Russia

    V. V. Yartsev & A. V. Samoylova

Authors
  1. A. A. Gostyukhina
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  2. V. V. Yartsev
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  3. A. V. Samoylova
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  4. M. A. Bolshakov
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  5. S. S. Evseeva
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  6. V. M. Mochalova
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  7. K. V. Zaitsev
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  8. O. P. Kutenkov
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  9. V. V. Rostov
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Corresponding author

Correspondence to A. A. Gostyukhina.

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Conflict of interest. The authors declare that they have no conflicts of interest.

Statement on the welfare of animals. The study was performed in accordance with the ethical standards of work with laboratory animals (ETS no. 123, 2007) and the sanitary rules for the design, equipment and maintenance of experimental biological clinics (Rules of Laboratory Practice in the Russian Federation). The research has been performed on the basis of permission of the Bioethics Commission of the Biological Institute of the NR TSU (Protocol no. 15 from June 14, 2019).

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Gostyukhina, A.A., Yartsev, V.V., Samoylova, A.V. et al. Histological Assessment of the Laboratory Rats Skin after Thermal Damages Treated with Nanosecond Microwave Pulses. Biol Bull Russ Acad Sci 50, 973–977 (2023). https://doi.org/10.1134/S1062359023601465

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  • DOI: https://doi.org/10.1134/S1062359023601465

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