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Determination of a series of nonsteroidal anti-inflammatory drugs using the sensitized luminescence of lanthanides

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Abstract

The spectral-luminescent characteristics of a series of nonsteroidal anti-inflammatory drugs (NSAID) and their complexes with Eu(III) and Tb(III) have been studied. A possibility of NSAID determination using the sensitized luminescence of lanthanides has been shown. A synergistic effect of the impact of trioctylphosphine oxide (TOPO) and Triton X-100 on the luminescence intensity of mixed-ligand complexes La(III)-NSAID-TOPO in a micellar medium (Triton X-100), used as analytical forms, has been found. The limits of detection for NSAID in various dosage forms are from 0.012 to 2.0 μg/mL.

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Authors and Affiliations

  1. Bogatsky Physicochemical Institute, National Academy of Sciences of Ukraine, Lyustdorfskaya doroga 86, Odessa, 65080, Ukraine

    A. V. Egorova, I. I. Leonenko, Yu. V. Skripinets & V. P. Antonovich

  2. ODO INTERCHEM, Lyustdorfskaya doroga 86, Odessa, 65080, Ukraine

    A. V. Anelchyk

Authors
  1. A. V. Egorova
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  2. A. V. Anelchyk
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  3. I. I. Leonenko
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  4. Yu. V. Skripinets
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  5. V. P. Antonovich
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Correspondence to A. V. Egorova.

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Original Russian Text © A.V. Egorova, A.V. Anelchyk, I.I. Leonenko, Yu.V. Skripinets, V.P. Antonovich, 2015, published in Zhurnal Analiticheskoi Khimii, 2015, Vol. 70, No. 4, pp. 370–379.

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Egorova, A.V., Anelchyk, A.V., Leonenko, I.I. et al. Determination of a series of nonsteroidal anti-inflammatory drugs using the sensitized luminescence of lanthanides. J Anal Chem 70, 440–449 (2015). https://doi.org/10.1134/S1061934815040048

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  • DOI: https://doi.org/10.1134/S1061934815040048

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