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Central Autonomic Network

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Abstract

The review analyzes data on the connections and functions of the structures of the central nervous system that form the central autonomic network (CAN), namely the prefrontal cortex, the extended amygdala, the hypothalamus, the central gray matter, the nucleus of the solitary tract, and the ventrolateral region of the medulla oblongata. We consider main properties of the CAN, such as morphological and neurochemical complexity, the presence of several outputs, and state-dependence. It is concluded that the main, but not the only function of the CAN is to maintain homeostasis in the current and predicted behavioral context.

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Funding

The study was carried out as part of the research work under the Program “Fundamental Scientific Research for Long-Term Development and Ensuring the Competitiveness of Society and the State.” Topic 64.1 (0134-2019-0001) “Uncovering the mechanisms of interaction between molecular-cellular and systemic regulation of internal organs.”

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  1. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia

    V. G. Aleksandrov, E. A. Gubarevich, T. N. Kokurina, G. I. Rybakova & T. S. Tumanova

  2. Herzen State Pedagogical University, St. Petersburg, Russia

    T. S. Tumanova

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  1. V. G. Aleksandrov
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  2. E. A. Gubarevich
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  3. T. N. Kokurina
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Correspondence to V. G. Aleksandrov.

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Aleksandrov, V.G., Gubarevich, E.A., Kokurina, T.N. et al. Central Autonomic Network. Hum Physiol 48, 759–765 (2022). https://doi.org/10.1134/S0362119722600412

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