Abstract
Renal function and body composition, including fluids, were studied during space flight conditions imitation with five-day dry immersion in 14 apparently healthy men. Noninvasive research of water spaces of the body was performed using methods of bioimpedance analysis (BIA). It was shown that renal excretion of fluids increased and negative aqueous balance developed during dry immersion. Bioimpedance research revealed decreased volume of the total body and the extracellular fluids, and the amount of circulating plasma also decreased. Thus, under the conditions of immersion, hypohydration developed in the body. In the recovery period, these changes in the hydration level rapidly returned to the initial values. The lean body mass during immersion was reduced insignificantly and the amount of fat, in contrast, exceeded the baseline levels. Furthermore, the experiment showed technical impossibility to obtain reliable impedancemetry data under the dry immersion conditions.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Glantz, S.A., Primer of Biostatistics, McGraw-Hill, 2005, 7th edition.
Kozlovskaya, I.B., Basic and applied tasks of immersion studies, Aviakosm. Ekol. Med., 2008, vol. 42, no. 5, p. 3.
Larina, I.M., Custaud, M.-A., Pastushkova, L.Kh., et al., The water-electrolyte metabolism, kidney function, and skin microvessels during seven-day dry immersion, Aviakosm. Ekol. Med., 2008, vol. 42, no. 5, p. 29.
Lobachik, V.I., Zhidkov, V.V., and Abrosimov, S.V., The state of the body fluid phases during 120-day head-down-tilt bed rest, Kosm. Biol. Aviakosm. Med., 1989, vol. 23, no. 5, p. 57.
Nikolaev, D.V., Smirnov, A.V., Bobrinskaya, I.G., and Rudnev, S.G., Bioimpedansnyi analiz sostava tela cheloveka (Bioimpedance Analysis of Human Body Composition), Moscow, 2009.
Noskov, V.B., Redistribution of bodyly fluids under conditions of weightlessness and in microgravity models. Hum. Physiol., 2013, vol. 39, no. 7, pp. 698.
Noskov, V.B., Kotov, A.N., Morukov, B.V., et al., Bioimpedance analysis of fluids and body composition under the conditions of short-term space flight or hypokinesia, Hum. Physiol., 2006, vol. 32, no. 5, p. 622.
Noskov, V.B., Lobachik, V.I., and Chepushtanov, S.A., The volume of extracellular fluid under conditions of long-term space flights, Hum. Physiol., 2000, vol. 26, no. 5, p. 600.
Noskov, V.B., Nichiporuk, I.A., and Grigoryev, A.I., Dynamics of liquid media and body composition under the conditions of extended space flight (bioimpedance analysis), Aviakosm. Ekol. Med., 2007, vol. 41, no. 3, p. 3.
Shul’zhenko, I.B. and Vil’-Vil’yams, I.F., The possibility to carry out long-term water immersion with the use of the dry immersion method, Kosm. Biol. Aviakosm. Med., 1976, vol. 10, no. 2, p. 32.
Dill, D.B. and Costill, D.L., Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration, J. Appl. Physiol., 1974, vol. 37, p. 247.
Electrical bioimpedance methods: Applications to medicine and biotechnology, Ann. N.Y. Acad. Sci., 1999, vol. 873.
Fortney, S.M., Hyatt, K.H., Davis, J.E., and Vogel, J.M., Changes in body fluid compartments during a 28-day bed rest, Aviat. Space Environ. Med., 1991, vol. 62, no. 2, p. 97.
Novosiolova, N.M., Custaud, M.-A., Tomilovskaya, E.S., et al., Long-term dry immersion: Review and prospects, Eur. J. Appl. Physiol., 2010, vol. 94, p. 1750.
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © V.B. Noskov, I.M. Larina, L.Kh. Pastushkova, I.V. Dobrokhotov, O.A. Valeeva, M. Coupe, M.-A. Custaud, A.M. Novoselova, 2011, published in Aviakosmicheskaya i Ekologicheskaya Meditsina, 2011, Vol. 45, No. 6, pp. 22–26.
Rights and permissions
About this article
Cite this article
Noskov, V.B., Larina, I.M., Pastushkova, L.K. et al. Functioning of the kidneys and human body fluids during five-day immersion. Hum Physiol 40, 737–740 (2014). https://doi.org/10.1134/S0362119714070172
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S0362119714070172