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Synergism and antagonism in extracting local anesthetics from aqueous media with mixtures of solvents

  • Physical Chemistry of Separation Processes. Chromatography
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Abstract

The extraction of local anesthetics from aqueous media with mixtures of solvent is examined and its synergistic and antagonistic effects are determined. Synergism parameters, separation factors, constants for the formation of anesthetic complexes, and solvate numbers are calculated.

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Correspondence to P. T. Sukhanov.

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Original Russian Text © P.T. Sukhanov, T.V. Chibisova, Ya.I. Korenman, 2014, published in Zhurnal Fizicheskoi Khimii, 2014, Vol. 88, No. 12, pp. 2012–2016.

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Sukhanov, P.T., Chibisova, T.V. & Korenman, Y.I. Synergism and antagonism in extracting local anesthetics from aqueous media with mixtures of solvents. Russ. J. Phys. Chem. 88, 2220–2224 (2014). https://doi.org/10.1134/S0036024414120334

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  • DOI: https://doi.org/10.1134/S0036024414120334

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