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Photoreactivation of UV-exposed Escherichia coli K12 AB1886 uvrA6 via luminescence of Photobacterium leiognathi luciferase

  • Molecular Cell Biology
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Abstract

Bioluminescence induced by luciferases of marine bacteria promotes repair of UV-damaged DNA in Escherichia coli AB1886 uvrA6. Bacterial photolyase, which implements photoreactivation activity, was identified as a major contributor to DNA repair. However, a UV-induced increase in bioluminescence (SOS induction) of bacterial cells was insufficient for efficient photoreactivation.

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Authors and Affiliations

  1. GosNIIgenetika State Research Center, Moscow, 117545, Russia

    O. E. Melkina, V. Yu. Kotova, I. V. Manukhov, K. S. Pustovoit & G. B. Zavilgelsky

  2. Moscow Institute of Physics and Technology (State University), Dolgoprudnyi, Moscow Region, 141700, Russia

    M. N. Konopleva & I. V. Manukhov

Authors
  1. O. E. Melkina
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  2. V. Yu. Kotova
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  3. M. N. Konopleva
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  4. I. V. Manukhov
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  5. K. S. Pustovoit
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  6. G. B. Zavilgelsky
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Corresponding author

Correspondence to G. B. Zavilgelsky.

Additional information

Original Russian Text © O.E. Melkina, V.Yu. Kotova, M.N. Konopleva, I.V. Manukhov, K.S. Pustovoit, G.B. Zavilgelsky, 2015, published in Molekulyarnaya Biologiya, 2015, Vol. 49, No. 6, pp. 1035–1040.

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Melkina, O.E., Kotova, V.Y., Konopleva, M.N. et al. Photoreactivation of UV-exposed Escherichia coli K12 AB1886 uvrA6 via luminescence of Photobacterium leiognathi luciferase. Mol Biol 49, 928–932 (2015). https://doi.org/10.1134/S0026893315060175

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  • DOI: https://doi.org/10.1134/S0026893315060175

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