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Inhibitory Action of Low-Molecular Chitosan on Growth of Bacteria with Different Tinctorial Properties

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Abstract—

Inhibitory effect of chitosan (molecular mass 28 kDa, deacetylation 94%) and of its quaternized derivative with 60% substitution on bacteria of various taxonomic groups was investigated. Bacteria differing in the cell wall surface characteristics and affinity to dyes were found to differ in their sensitivity to chitosan. Correlation dependencies between antibacterial activity of quaternized chitosan and the surface characteristics of bacterial cell walls were revealed.

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REFERENCES

  1. Dolgonosov, A.M., A model of a general type intermolecular interaction between a molecule and the liquid phase based on the theory of generalized charge, Sorbtion. Khromatogr. Protsessy, 2020, vol. 20, no. 3, pp. 343‒361.

    CAS  Google Scholar 

  2. Eroshenko, D.V. and Korobov, V.P., Adhesion of staphylococci: the first step to biofilm formation, Usp. Sovr. Biol., 2017, vol. 137, no. 1, pp. 100‒112.

    Google Scholar 

  3. Evans, M.L., Gichana, E., Zhou, Y., and Chapman, M.R., Bacterial amyloids, Methods Mol. Biol., 2018, vol. 1779, pp. 267‒288.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Khitin i khitozan: poluchemie, svoistva i primenenie (Chitin and Chitosan: Production, Properties, and Application), Skrybin, K.G., Vikhoreva, G.A., and Varlamov, V.P., Eds., Moscow: Nauka, 2002.

    Google Scholar 

  5. Krasavtsev, V.E., Kuprina, E.E., Maslova, G.V., and Albulov, A.I., Chitin and chitosan. Sources and main processing techniques, in Khitosan (Chitosan), Skrybin, K.G., Mikhailov, S.N., and Varlamov, V.P., Eds., Moscow: Bioengineering Center, 2013, pp. 18‒48.

    Google Scholar 

  6. Krasil’nikov, A.P. and Romanovskaya, T.R., Mikrobiologicheskii slovar’-spravochnik (Microbiological Reference Dictionary), Minsk: Asar, 1999, 2nd ed.

  7. Pan’kova, N.V., Polyudova, T.V., Lemkina, L.M., and Korobov, V.P., Hydrophobic and donor-acceptor properties of the surface of warnerin-sensitive or resistant staphylococcus cells, Microbiology (Moscow), 2011, vol. 80, pp. 573‒575.

    Article  Google Scholar 

  8. Rosenberg, M., Bacterial adherence to hydrocarbons: a useful technique for studying cell surface hydrophobicity, FEMS Microbiol. Lett., 1984, vol. 22, pp. 289‒295.

    Article  CAS  Google Scholar 

  9. Schneewind, O. and Missiakas, D., Lipoteichoic acids, phosphate-containing polymers in the envelope of gram-positive bacteria, J. Bacteriol., 2014, vol. 196, pp. 1133‒1142.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Shagdarova, B., Lunkov, A., Il’ina, A., and Varlamov, V., Investigation of the properties of N-[(2-hydroxy-3-trimethylammonium) propyl] chloride chitosan derivatives, Int. J. Biol. Macromol., 2019, vol. 124, pp. 994‒1001.

    Article  CAS  PubMed  Google Scholar 

  11. Shagdarova, B.T., Il’ina, A.V., and Varlamov, V.P., Antibacterial activity of alkylated and acylated derivatives of low-molecular weight chitosan, Appl. Biochem. Microbiol., 2016, vol. 52, pp. 222‒225.

    Article  CAS  Google Scholar 

  12. Shul’gina, M.V., Narvskaya, O.V., and Mokrousov, I.V., Patogennye i uslovno-patogennye mikobakterii (Pathogenic and Opportunistic Mycobacteria), Moscow: NEW TERRA, 2018.

  13. Tepper, E.Z., Shil’nikova, V.K., and Pereverzeva, G.I., Praktikum po mikrobiologii (Practical Course in Microbiology), Moscow: Kolos, 1972.

  14. Vadyvaloo, V. and Otto, M., Molecular genetics of Staphylococcus epidermidis biofilms on indwelling medical devices, Int. J. Artif. Organs, 2005, vol. 28, pp. 1069‒1078.

    Article  CAS  PubMed  Google Scholar 

  15. Yusupova, R.I., Kurmaeva, A.I., Potapova, M.V., Kulagina, E.M., and Barabanov, V.P., Microbial cell suspension as a colloidal system. Part 2. Surface charge and electrokinetic properties of yeast and bacterial suspensions, Vestn. Kazan. Tekhnol. Univ., 2013, vol. 16, no. 4, pp. 189‒191.

    CAS  Google Scholar 

  16. Zaitseva, E.A., Sharkova, V.A., Digo, R.N., Voropaeva, N.M., and Bronnikov, Yu.N., Morfologicheskie i tinktorial’nye svoistva bakterii (Morphological and Tinctorial Properties of Bacteria), Vladivostok: Meditsina DV, 2015.

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Funding

This work was supported by the Ministry of Education and Science of the Russian Federation in terms of the State Assignments concerned with Molecular Mechanisms of Microbial Adaptation to Environmental Factors, Research and Technological Development Registration no. АААА-А19-119112290009-1, and Production and Investigation of Physiologically Active Compounds, Biopolymers, their Derivatives, and Composites Used in Medicine and Agriculture, Research and Technological Development Registration no. 122041100009-4.

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Authors and Affiliations

  1. Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Ural Branch, Russian Academy of Sciences, 614081, Perm, Russia

    V. P. Korobov & A. L. Esaev

  2. Institute of Bioengineering, Research Center of Biotechnology, Russian Academy of Sciences, 119071, Moscow, Russia

    B. Ts. Shagdarova & V. P. Varlamov

  3. Kazan Federal University, 420008, Kazan, Russia

    V. P. Varlamov

  4. Perm State Agro-Technological University, 614990, Perm, Russia

    T. V. Polyudova

Authors
  1. V. P. Korobov
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  2. B. Ts. Shagdarova
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  3. V. P. Varlamov
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  4. A. L. Esaev
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  5. T. V. Polyudova
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Corresponding author

Correspondence to T. V. Polyudova.

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The authors declare that they have no conflict of interests. This article does not contain any studies involving animals performed by any of the authors.

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Translated by A. Oleskin

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Korobov, V.P., Shagdarova, B.T., Varlamov, V.P. et al. Inhibitory Action of Low-Molecular Chitosan on Growth of Bacteria with Different Tinctorial Properties. Microbiology 92, 215–220 (2023). https://doi.org/10.1134/S0026261722603347

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  • DOI: https://doi.org/10.1134/S0026261722603347

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