Abstract
Upon irradiation ascorbic acid and 5,6-O-isopropylidene-2,3-O-dimethylascorbic acid are capable of lowering the yields of the main products of γ-radiolysis of oxygen-saturated ethanol or its aqueous solutions at pH 7 by virtue of reduction of peroxyl radicals and oxidation of α-hydroxyethyl radicals, respectively. In addition to the ability to inhibit radiation-induced transformations of oxygenated ethanol and its aqueous solutions at pH 7, ascorbic acid can participate in reactions resulting in the formation of additional amounts of reactive oxygen species, which must be taken into account when considering its role in free-radical processes in biological systems.
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References
Halliwell, B. and Gutteridge, J.M.C., Free radicals in Biology and Medicine, Oxford: Oxford University Press, 1999.
Buettner, G.R. and Jurkiewicz, B.A., Radiat. Res., 1996, vol. 145, p. 532.
Davies, M.B., Austin, J., and Patridge, D.A., Vitamin C: Its Chemistry and Biochemistry, Cambridge: The Royal Chemical Society, 1991.
Childs, A., Jacobs, C., Kaminski, T., Halliwell, B., and Leeuwenburgh, C., Free Rad. Boil. Med, 2001, vol. 31, no. 6, p. 745.
Shadyro, O.I., Sosnovskaya, A.A., Edimecheva, I.P., Ostrovskaya, N.I., Kazem, K.M., Hryntsevich., I.B., and Alekseev A.V, Bioorg. Med. Chem. Lett., 2007, vol. 17, no. 22, p. 6383.
Shadyro, O.I., Sosnovskaya, A.A., Edimecheva, I.P., Ostrovskaya, N.I., and Kazem, K.M., High Energy Chem., 2008, vol. 42, no. 2, p. 83.
Brinkevich, S.D. and Shadyro, O.I., High Energy Chem., 2008, vol. 42, no. 4, p. 255.
Brinkevich, S.D., Sverdlov, R.L., and Shadyro, O.I., High Energy Chem., 2013, vol. 47, no. 1, p. 12.
Egerton, SirA., Everett, A.J., Minkoff, G.J., Rudrakanhana, S., and Salooja, K.C., Anal. Chim. Acta, 1965, vol. 10, p. 422.
Freeman, G.R., Radiation Chemistry of Ethanol: A Review of Data on Yields, Reaction Rate Parameters, and Spectral Properties of Transients Washington: NBS, 1974.
Ledru, S. and Boujtita, M., Bioelectrochemistry, 2004, vol. 64, p. 71.
Bielski, B.H.J., Allen, A.O., and Schwarz, H.A., J. Am. Chem. Soc., 1981, vol. 103, no. 12, p. 3516.
Cabelli, D.E. and Bielski, AB.H.J., Radiat. Phys. Chem., 1984, vol. 23, no. 4, p. 419.
Bielski, B.H.J., Adv. Chem. Ser., 1982, vol. 200, p. 81.
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Original Russian Text © S.D. Brinkevich, 2015, published in Khimiya Vysokikh Energii, 2015, Vol. 49, No. 2, pp. 83–88.
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Brinkevich, S.D. Effect of ascorbic acid and its derivatives on the radiation-induced transformations of oxygenated ethanol and its aqueous solutions. High Energy Chem 49, 77–82 (2015). https://doi.org/10.1134/S0018143915020034
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DOI: https://doi.org/10.1134/S0018143915020034