Abstract
Using the audiogenic seizure prone Krushinsky–Molodkina rat strain, it was demonstrated that short-term (5 min) exposure of 14-day-old pups to an elevated temperature (42°C) resulted in a significant decrease in audiogenic seizure severity at the age of 1 month. Presumably, this effect is determined by the activation of the heat-shock protein system (stress proteins).
Similar content being viewed by others
References
Poletaeva, I.I., Perepelkina, O.V., Boyarshinova, O.S., et al., Ontogenez, 2012, vol. 43, no. 6, pp. 387–400.
Semiokhina, A.F., Fedotova, I.B., and Poletaeva, I.I., Zh. Vyssh. Nervn. Deyat., 2006, vol. 56, no. 3, pp. 298–316.
Fedotova, I.B., Surina, N.M., Malikova, L.A., et al., Zh. Vyssh. Nervn. Deyat., 2008, vol. 58, no. 5, pp. 620–627.
Khudik, K.A., Pastukhov, Yu.F., and Guzhova, I.V., Ros. Fiziol. Zh. im. I.M. Sechenova, 2011, vol. 97, no. 11, pp. 1237–1246.
Ajdev, S.R. and Sharp, F.R., Toxicol. Pathol., 2000, vol. 28, no. 1, pp. 105–112.
Ammon-Treiber, S., Grecksch, G., Angelidis, C., et al., Naunyn-Schmiedeberg’s Arch. Pharmacol., 2007, vol. 375, pp. 115–121.
Brown, I.R., J. Neurosci. Res., 1990, vol. 27, no. 3, pp. 247–255.
Faingold, C.L., Adv. Neurol., 1999, vol. 79, pp. 311–321.
Ennaceur, A. and Chazot, P.L., Pharmacol. Res. Perspect., 2016, vol. 4, no. 2, p. e00223. doi 10.1002/prp2.223.eCollection 2016
Ekimova, I.V., Nitsinskaya, L.E., Romanova, I.V., et al., J. Neurochem., 2010, vol. 115, no. 4, pp. 1035–1044. doi 10.1111/j.1471-4159.2010.06989.x
Hessel, E.V.S., van Gassen, K.L.I., Wolterink-Donselaar, I.G., et al., Genes Brain Behav., 2009, vol. 8, pp. 248–255.
N’Gouemo, P., Yasuda, R.P., and Faingold, C.L., Brain Res., 2010, vol. 1308, pp. 153–157. doi 10.1016/j.brainres. 2009.10.019 PMCID: PMC2793592
Xu, J.L., Fan, Y., Li, L., et al, Epilepsy Res., 2013, vol. 103, no. 3, pp. 311–317. doi 10.1016/j.eplepsyres. 2013.07.002
Author information
Authors and Affiliations
Corresponding author
Additional information
Published in Russian in Doklady Akademii Nauk, 2017, Vol. 472, No. 1, pp. 109–111.
This article was translated by the authors.
Rights and permissions
About this article
Cite this article
Fedotova, I.B., Nikolaev, G.M., Kostyna, Z.A. et al. Remote effects of short-term neonatal hyperthermia in Krushinsky–Molodkina rats prone to audiogenic seizures strain. Dokl Biol Sci 472, 1–3 (2017). https://doi.org/10.1134/S001249661701001X
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S001249661701001X