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Remote effects of short-term neonatal hyperthermia in Krushinsky–Molodkina rats prone to audiogenic seizures strain

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Abstract

Using the audiogenic seizure prone Krushinsky–Molodkina rat strain, it was demonstrated that short-term (5 min) exposure of 14-day-old pups to an elevated temperature (42°C) resulted in a significant decrease in audiogenic seizure severity at the age of 1 month. Presumably, this effect is determined by the activation of the heat-shock protein system (stress proteins).

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Correspondence to I. I. Poletaeva.

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Published in Russian in Doklady Akademii Nauk, 2017, Vol. 472, No. 1, pp. 109–111.

This article was translated by the authors.

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Fedotova, I.B., Nikolaev, G.M., Kostyna, Z.A. et al. Remote effects of short-term neonatal hyperthermia in Krushinsky–Molodkina rats prone to audiogenic seizures strain. Dokl Biol Sci 472, 1–3 (2017). https://doi.org/10.1134/S001249661701001X

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  • DOI: https://doi.org/10.1134/S001249661701001X

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