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The Mechanisms of Chemoreception and Thermoreception in the Grueneberg Ganglion

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Abstract

The Grueneberg ganglion is one of the peripheral parts of the olfactory sensory system that specializes in detecting life-threatening stimuli. This article focuses on the chemoreceptors of ganglion neurons and their associated signaling pathways, which together provide a multimodal receptor function. The molecular organization of the receptor apparatus of neurons of this organ undergoes significant changes during ontogenesis, providing a shift in specialization in the direction from thermoreception in the neonatal period to chemoreception at later stages of development.

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Funding

This work was carried out with the financial support of the Program of Fundamental Scientific Research of State Academies for 2014–2020 (GP-14, section 63).

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Authors and Affiliations

  1. Pavlov Institute of Physiology, Russian Academy of Sciences, 199034, St. Petersburg, Russia

    E. V. Bigdai, V. O. Samoilov & A. A. Sinegubov

Authors
  1. E. V. Bigdai
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  2. V. O. Samoilov
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  3. A. A. Sinegubov
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Corresponding author

Correspondence to E. V. Bigdai.

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The authors declare that there is no conflict of interest.

COMPLIANCE WITH ETHICAL STANDARDS

This paper does not describe studies using humans and animals as objects.

Additional information

Translated by E. Puchkov

Abbreviations: GG, Grueneberg ganglion; OMP, olfactory marker protein; TAAR, trace amine-associated receptors.

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Bigdai, E.V., Samoilov, V.O. & Sinegubov, A.A. The Mechanisms of Chemoreception and Thermoreception in the Grueneberg Ganglion. BIOPHYSICS 66, 91–97 (2021). https://doi.org/10.1134/S0006350921010139

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  • DOI: https://doi.org/10.1134/S0006350921010139

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