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On the individualization of therapeutic doses of optical radiation according to changes in the parameters of blood oxygenation

  • Biophysics of Complex Systems
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Abstract

The effects of in vivo optical laser irradiation of blood from different patients were studied. The objects of the research were three series of blood samples from patients treated using extracorporeal UV blood irradiation, intravenous blood laser irradiation, and over-vein blood laser irradiation. The optic oximetry data and the gas composition of venous blood were compared before and after the irradiation. The positive and negative effects of blood irradiation on both the oxygen-exchange characteristics in individual patients and the content of some metabolic products were studied. It was shown that the changes in these parameters at the same power dose depended on both the individual initial level of venous blood hemoglobin oxygen saturation and the photoinduced changes in blood, which objectively reflect the individual sensitivity of patients to the action of optical radiation on blood and can be used for the assessment of the efficiency of phototherapy.

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Abbreviations

PHT:

photohemotherapy

UBI:

ultraviolet blood irradiation with UV lamp

IBLI:

intravenous blood laser irradiation

SBLI:

supravenous blood laser irradiation

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Authors and Affiliations

  1. Stepanov Institute of Physics, National Academy of Sciences of Belarus, pr. Nezavisimosti 68, Minsk, 220072, Belarus

    G. A. Zalesskaya

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  1. G. A. Zalesskaya
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Correspondence to G. A. Zalesskaya.

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Original Russian Text © G.A. Zalesskaya, 2015, published in Biofizika, 2015, Vol. 60, No. 3, pp. 534–541.

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Zalesskaya, G.A. On the individualization of therapeutic doses of optical radiation according to changes in the parameters of blood oxygenation. BIOPHYSICS 60, 433–438 (2015). https://doi.org/10.1134/S0006350915030227

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  • DOI: https://doi.org/10.1134/S0006350915030227

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