We studied the effect of therapeutic doses of optical radiation on the hematological parameters of blood irradiated in vivo: hemoglobin concentration, hematocrit, and the number of erythrocytes in the peripheral blood of patients during courses of extracorporeal, overvein, and intravenous blood irradiation and after treatment. The reversible changes during the procedures were found to differ from the changes obtained after treatment completion. At the end of the treatment course, the hematological parameters had changed in different directions and became higher, the same, or lower than the initial parameters depending on the initial parameters and photoinduced changes in blood oxygenation. A compensatory effect was found for photohemotherapy on oxygen-dependent processes altering the oxygen inflow into cells as well as the generation of active oxygen species and their inhibition by antioxidant systems.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
G. A. Zalesskaya and V. S. Ulaschik, Zh. Prikl. Spektrosk., 76, No. 1, 51–75 (2009) [G. A. Zalesskaya and V. S. Ulaschik, J. Appl. Spectrosc., 76, No. 1, 44–65 (2009)].
G. A. Zalesskaya, in: V. S. Ulashchik (Ed.), Blood Photomodification by Doses of Optical Irradiation [in Russian], Belorusskaya Nauka, Minsk (2014).
G. A. Zalesskaya, Biofizika, 60, No. 3, 534–541 (2015).
I. M. Baibekov, R. Sh. Mavlyan Khodzhaev, A. G. Éretekis, and S. V. Moskvin, Erythrocytes in the Norm, Pathology and Upon Laser Treatment [in Russian], Triada, Tver, Russia (2008).
V. I. Karandashov, N. N. Kvitko, O. I. Slinchenko, and N. P. Aleksandrov, Byul. Éksper. Biol. Med., No. 5, 530–532 (1993).
I. M. Baibekov. A. F. Ibragimov, and A. I. Baibekov, Bull. Exper. Biol. Med., 152, No. 6, 756–759 (2007).
Y. Cui, Z. Guo, Y. Zheng, Y. Qiao, J. Cai, and S. Liu, Acta Biochem. Biophys. Sin., 39, 484–489 (2007).
E. K. Naumenko, Zh. Prikl. Spektrosk., 76, No. 4, 557–563 (2009) [E. K. Naumenko, J. Appl. Spectrosc., 76, 528–535 (2009)].
A. B. Rubin, Biophysics of Cell Processes [in Russian], Moscow University, Moscow (2002).
N. A. Davletkil′deev and G. S. Trushnikov, Vestn. Omsk. Univ. Med. Biofizika, No. 4, 45–48 (2008).
V. I. Karandashov, E. B. Petukhov, and V. S. Zrodnikov, in: N. R. Paleev (Ed.), Phototherapy [in Russian], Meditsina, Moscow (2001).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 84, No. 3, pp. 428–433, May–June, 2017.
Rights and permissions
About this article
Cite this article
Zalesskaya, G.A., Laskina, O.V. Correcting Effect of Therapeutic Doses of Optical Radiation on Hematological Parameters of Blood Irradiated In Vivo . J Appl Spectrosc 84, 448–451 (2017). https://doi.org/10.1007/s10812-017-0490-7
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10812-017-0490-7