Skip to main content
Log in

Non-Newtonian flow of blood in a catheterized bifurcated stenosed artery

  • Published:
Journal of Bionic Engineering Aims and scope Submit manuscript

Abstract

The paper is devoted to study the non-Newtonian behavior of blood flowing in an artery having a stenosis, in a situation when a catheter has been inserted into it. The blood rheology is described by Herschel-Bulkley fluid model. The flow configuration is constructed by choosing suitable curvature at the lateral junction, where the flow separation is initiated. The effects of insertion of catheter and that of yield stress of blood on the velocity distribution, rate of flow and flow resistance of blood, distribution of shear stress at the arterial wall and the location of yield plane are investigated. The results provide some useful information for the prediction/treatment of some arterial diseases and circulatory disorders of the cardiovascular system, in a situation, when a stenosis is developed on the endothelium of the daughter artery / bifurcated artery. The study reveals that if the ratio between the radii of the catheter and the artery is increased, the shear stress at the arterial wall diminishes. However, when the bifurcation angle is increased, the wall shear stress is enhanced.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Fry D L. Acute vascular endothelial change associated with increased blood velocity gradients. Circulation Research, 1968, 22, 165–197.

    Article  Google Scholar 

  2. Caro C G, Fitz-Gerald J M, Schroter R C. Atheroma and arterial wall shear observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis. Proceedings of the Royal Society B, 1971, 177, 109–159.

    Article  Google Scholar 

  3. Lou Z, Yang W J. Bio-fluid dynamics at arterial bifurcation. Critical Review in Biomedical Engineering, 1992, 19, 455–493.

    Google Scholar 

  4. Lou Z, Yang W J. A computer simulation of the blood at the aortic bifurcation with flexible walls. ASME Journal of Biomechanical Engineering, 1993, 115, 306–315.

    Article  Google Scholar 

  5. Duncan D D, Bargeron C B, Borchardt S E, Deters S E, Gearhart S A, Mark F F, Friedman M H. The effect of compliance on wall shear in casts of a human aortic bifurcation. ASME Journal of Biomechanical Engineering, 1990, 112, 183–188.

    Article  Google Scholar 

  6. Ku D N, Giddens D P. Pulsatile flow in a model carotid bifurcation. Arteriosclerosis, 1983, 3, 31–39.

    Article  Google Scholar 

  7. Ku D N, Giddens D P. Laser Doppler anemometer measurements of pulsatile flow in a model carotid bifurcation. Journal of Biomechanics, 1987, 20, 407–421.

    Article  Google Scholar 

  8. Nadeem S, Ijaz S. Mechanics of biological blood flow analysis through curved artery with stenosis. Journal of Mechanics in Medicine and Biology, 2016, 16, 1650024.

    Article  Google Scholar 

  9. Misra J C, Shit G C. Role of slip velocity in blood flow through stenosed arteries: A non-Newtonian model. Journal of Mechanics in Medicine and Biology, 2007, 7, 337–353.

    Article  Google Scholar 

  10. Misra J C, Sinha A, Shit G C. Theoretical analysis of blood flow through an arterial segment having multiple stenoses. Journal of Mechanics in Medicine and Biology, 2008, 8, 265–279.

    Article  Google Scholar 

  11. Khan A A, Sohail A, Rashid S, Rashidi M M, Khan N A. Effects of slip condition, variable viscosity and inclined magnetic field on the peristaltic motion of a non-Newtonian fluid in an inclined asymmetric channel. Journal of Applied Fluid Mechanics, 2016, 9, 1381–1393.

    Article  Google Scholar 

  12. Keimanesh M, Rashidi M M, Chamkha A J, Jafari R. Study of a third grade non-Newtonian fluid flow between two parallel plates using the multi-step differential transform method. Computers and Mathematics with Applications, 2011, 62, 2871–2891.

    Article  MathSciNet  MATH  Google Scholar 

  13. Rashidi M M, Rastegari M T, Asadi M, Beg O A. A study of non-Newtonian flow and heat transfer over a non-isothermal wedge using the homotopy analysis method. Chemical Engineering Communications, 2012, 199, 231–256.

    Article  Google Scholar 

  14. Back L H. Estimated mean flow resistance increase during coronary artery catheterization. Journal of Biomechanics, 1994, 27, 169–175.

    Article  Google Scholar 

  15. Bjorno L, Petterson H. Hydro-and hemodynamic effects of catheterization of vessels. I. An experimental model. Acta Radiologia Diagnosis, 1976, 17, 511–525.

    Article  Google Scholar 

  16. Hellsten S, Petterson H. Hydro-and hemodynamic effects of catheterization of vessels: IV catheterization in the dog. Acta Radiologia Diagnosis, 1977, 18, 17–24.

    Article  Google Scholar 

  17. Karahalios G T. Some possible effects of a catheter on the arterial wall. Medical Physics, 1990, 17, 922–925.

    Article  Google Scholar 

  18. Jayaraman G, Tiwari K. Flow in a catheterized curved artery. Medical & Biological Engineering & Computing, 1995, 33, 720–724.

    Article  Google Scholar 

  19. Misra J C, Chakravarty S. Flow in arteries in the presence of stenosis. Journal of Biomechanics, 1986, 19, 907–918.

    Article  Google Scholar 

  20. Misra J C, Patra M K, Misra S C. A non-Newtonian fluid model for blood flow through arteries under stenotic conditions. Journal of Biomechanics, 1993, 26, 1129–1141.

    Article  Google Scholar 

  21. Misra J C, Sinha A. Effect of thermal radiation on MHD flow of blood in a permeable capillary in stretching motion. Heat and Mass Transfer, 2013, 49, 617–628.

    Article  Google Scholar 

  22. Misra J C, Chandra S, Shit G C, Kundu P K. Electro-osmotic oscillatory flow of micropolar fluid in a micro-channel: Application to dynamics of blood flow in microfluidic de vices. Applied Mathematics and Mechanics, 2014, 35, 749–766.

    Article  MATH  Google Scholar 

  23. Misra J C, Maiti S. Peristaltic pumping of blood through small vessels of varying cross-section. ASME Journal of Applied Mechanics, 2012, 79, 061003.

    Article  Google Scholar 

  24. Misra J C, Shit G C, Chandra S, Kundu P K. Hydromagnetic flow and heat transfer of a second-grade viscoelastic fluid in a channel with oscillatory channel walls: Application to dynamics of blood flow. Journal of Engineering Mathematics, 2011, 59, 91–100.

    Article  MATH  Google Scholar 

  25. Misra J C, Shit G C. Flow of a biomagnetic viscoelastic fluid in a channel with stretching walls. ASME Journal of Applied Mechanics, 2009, 76, 06106.

    Article  Google Scholar 

  26. Sinha A, Misra J C. MHD flow of blood through a dually stenosed artery: Effects of viscosity variation, variable hematocrit and velocity-slip. Canadian Journal of Chemical Engineering, 2014, 92, 23–31.

    Article  Google Scholar 

  27. Misra J C, Adhikary S D. MHD oscillatory channel flow, heat and mass transfer in a physiological fluid in presence of chemical reaction. Alexandria Engineering Journal, 2016, 55, 287–297.

    Article  Google Scholar 

  28. Saha R, Sarifuddin, Misra J C, Mandal P K. Impact of luminal flow on mass transport through coronary arteries: A study relevant to drug-eluting stent. International Journal of Mathematics and Computations, 2016, 27, 40–58.

    MathSciNet  Google Scholar 

  29. Misra J C, Chandra s, Herweig H. Flow of microploar fluid in a micro-channel under the action of an alternating electric current: Estimates of flow in bio-fluidic devices. Journal of Hydrodynamics, 2015, 27, 350–358.

    Article  Google Scholar 

  30. Kadowaki H, Hayase T, Funamoto K, Sone S, Shimazaki T, Jibiki T, Miyama K. Blood flow analysis in carotid artery bifurcation by two-dimensional ultrasonic-measurementintegrated simulation. Journal of Biomechanical Science and Engineering, 2015, 10, 14-00266.

    Article  Google Scholar 

  31. Akbar N S, Nadeem S. Blood flow analysis in tapered stenosed arteries with pseudoplastic characteristics. International Journal of Biomathematics, 2014, 7, 1450065.

    Article  MathSciNet  MATH  Google Scholar 

  32. Hye M A, Paul M C. A computational study on spiral blood flow i stenosed arteries with and without an upstream curved section. Applied Mathematical Modelling, 2015, 39, 4746–4766.

    Article  MathSciNet  Google Scholar 

  33. Srinivasacharya D, Rao M. Pulstile flow of couple stress fluid through a bifurcated artery. Ain Shams Engineering Journal, DOI: 10.1016/j.asej.2016.04.023. (in press)

  34. Sankar D S, Hemalatha K. A non-Newtonian fluid flow model for blood flow through a cathterized artery-Steady flow. Applied Mathematical Modelling, 2007, 31, 1847–1864.

    Article  MATH  Google Scholar 

  35. Sankar D S, Lee U. Two-fluid Herschel-Bulkley model for blood flow in catheterized arteries. Journal of Mechanical Science and Technology, 2008, 22, 1008–1018.

    Article  Google Scholar 

  36. Chakravarty S, Sen S. A mathematical model of blood flow in a catheterized artery with a stenosis. Journal of Mechanics in Medicine and Biology, 2009, 9, 377–410.

    Article  Google Scholar 

  37. Murray C D. The physiological principle of minimum work applied to the angle of branching or arteries. Journal of General Physiology, 1926, 9, 835–841.

    Article  Google Scholar 

  38. Lou Z, Yang W J. A computer simulation of the blood flow at the aortic bifurcation. Journal of Biomechanics, 1993, 26, 37–49.

    Article  Google Scholar 

Download references

Acknowledgment

This work was supported by the Science and Engineering Research Board, Department of Science and Technology, Government of India, New Delhi through Grant No. SB/S4: MS 864/14.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jagadis Chandra Misra.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Misra, J.C., Shit, G.C. & Pramanik, R. Non-Newtonian flow of blood in a catheterized bifurcated stenosed artery. J Bionic Eng 15, 173–184 (2018). https://doi.org/10.1007/s42235-017-0014-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s42235-017-0014-4

Keywords

Navigation