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MiRNA-202 Role in Reproductive System and Gynecological Cancers

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Indian Journal of Gynecologic Oncology Aims and scope Submit manuscript

Abstract

Introduction

MicroRNAs, also known as miRNAs, are small regulatory RNAs, and they also include many different types in terms of size and commission that do not code the proteins but are crucial for many biological activities, such as formation, regulation, and inhibition in biological pathways.

miRNA-202

Our aim in this study was to analyze miRNA-202 in reproductive system settings, including the formation and function of reproductive systems. MiRNA-202 has been identified as a tumor suppressor in ovarian, endometrial, and cervical malignancies; in addition, it is essential for follicular growth and oogenesis.

Conclusion

This study reviews the most recent evidence supporting the concept that dysregulation of miRNA-202 may contribute to gynecological malignancies.

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Acknowledgments

None.

Funding

This work was financially supported by Behbahan Faculty of Medical Sciences, Behbahan, Iran (Grant number: 401109).

Author information

Author notes

  1. Farzaneh Vahedi, Fatemeh Hasani, and Maryam Rezaee have equally contributed to this work, and both are first authors.

Authors and Affiliations

  1. Department of Medical Biotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran

    Farzaneh Vahedi & Maryam Rezaee

  2. Student Research Committee, Behbahan Faculty of Medical Sciences, Behbahan, Iran

    Fatemeh Hasani

  3. Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

    Marjan Nourigorji

  4. Department of Biology, Texas A&M University, College Station, TX, USA

    Ali Saber Sichani

  5. Reproductive Health Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran

    Hojat Ghasemnejad‐Berenji

  6. Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran

    Mortaza Taheri-Anganeh

  7. Student Research Committee, Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Seyyed Hossein Khatami

  8. Department of Molecular Medicine, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran

    Kamran Hosseini

  9. Behbahan Faculty of Medical Sciences, Behbahan, Iran

    Ahmad Movahedpour & Mostafa Moazamfard

Authors
  1. Farzaneh Vahedi
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  2. Fatemeh Hasani
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  3. Maryam Rezaee
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  8. Seyyed Hossein Khatami
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  9. Kamran Hosseini
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Corresponding authors

Correspondence to Ahmad Movahedpour or Mostafa Moazamfard.

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Vahedi, F., Hasani, F., Rezaee, M. et al. MiRNA-202 Role in Reproductive System and Gynecological Cancers. Indian J Gynecol Oncolog 22, 75 (2024). https://doi.org/10.1007/s40944-024-00833-w

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  • DOI: https://doi.org/10.1007/s40944-024-00833-w

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