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Extra Ovarian Adult Granulosa Cell Tumor: A Rare Clinical Case Report

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Abstract

Adult ovarian granulosa cell tumor is one of the rare types of malignant tumor, which arises from the sex cord granulosa cell of the ovary. The tumor can arise from different type of gonadal sex cord cells like thecal cells, Sertoli cells, granulosa cells and stromal cells. The specific type of granulosa cell tumor is comprised of thecal cells and fibroblasts. In our case report, we are reporting a case of 63-year-old women with granulosa cell tumor of low-grade malignancy.

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References

  1. Kaur K, Kaur M, Singla N, Kaur A. Bilateral ovarian adult granulosa cell tumor: a rare case presentation. Int J Curr Res. 2018;10(10):74591–2.

    Google Scholar 

  2. Joshi R, Baral G, Malla K. Ovarian adult granulosa cell tumor: a rare case report. Nepal J Obstet Gynaecol. 2018;13(1):57–60.

    Article  Google Scholar 

  3. Agius T, Gatt M, Falzon D, Babic D. A complex case of a granulosa cell tumour. BMJ Case Rep CP. 2021;14(12):e242224.

    Article  Google Scholar 

  4. Classification of tumors of the ovary. In: kurman RJ, Carcangiu ML, Herringtom CS, Younf RH, editors. WHO classifiaction of tumors. 4th edition. Lyon. IARC; 2014

  5. Ray-Coquard I, Morice P, Lorusso D, Prat J, Oaknin A, Pautier P, et al. Non epithelial ovarian cancer. ESMO clinicla practice guidelines for diagnosis, treatment and follow up. Ann oncol. 2018;29:1–18.

    Article  Google Scholar 

  6. Movahedi-Lankarani S, Kurman RJ. Calretinin, a more sensitive but less specific marker than α-inhibin for ovarian sex cord-stromal neoplasms: an immunohistochemical study of 215 cases. Am J Surg Pathol. 2002;26(11):1477–83.

    Article  PubMed  Google Scholar 

  7. Kottarathil VD, Antony MA, Nair IR, Pavithran K. Recent advances in granulosa cell tumor ovary: a review. Indian J Surg Oncol. 2013;4(1):37–47.

    Article  PubMed  Google Scholar 

  8. Moustaide H, Taheri H, Benkirane S, Saadi H, Mimouni A. Ovarian adult granulosa cell tumor: report of 3 cases. J Clin Case Rep. 2017;7:2.

    Google Scholar 

  9. Kayastha S, Chitrathara K, Sigdel B, Sanam P, Anupama S, Remi A, Augustine T, Peter BC. Adult granulosa cell tumor of ovary: clinical study of 10 cases. Indian J Gynecol Oncol. 2020;18:2.

    Article  Google Scholar 

  10. Miller BE, Barron BA, Wan JY. Prognostic factors in adult granulosa cell tumor of the ovary. Cancer. 1997;79:1951–5.

    Article  CAS  PubMed  Google Scholar 

  11. Lappöhn RE, Burger HG, Bouma J, Bangah M, Krans M, De Bruijn HW. Inhibin as a marker for granulosa-cell tumors. N Engl J Med. 1989;12:790–3.

    Article  Google Scholar 

  12. Salani R, Goodrich K, Song C, Grumbine FC. Three case reports of laparoscopic management of granulosa cell tumor with intraoperative rupture and subsequent upstaging. J Minim Invasive Gynecol. 2008;15:511–3.

    Article  PubMed  Google Scholar 

  13. Nakayama J, Saks E, Pelkofski E, Edwards J, Stine JE, Secord AA, Gehrig PA, Duska L. Laparoscopy compared to laparotomy in the management of granulosa cell tumors of the ovary. Gynecol Oncol. 2015;137:168.

    Article  Google Scholar 

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Acknowledgements

We the authors thank our pathology team for their efforts and suggestions. We extend our gratitude to Dr. Suraj Manjunath and Dr. Elvis Peter Joseph who were helpful in suggesting the case scenario. We thank patient for providing us with the case details.

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Correspondence to Y. C. Madhu.

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Dwajani, S., Rajeev, N., Shreya, M.S. et al. Extra Ovarian Adult Granulosa Cell Tumor: A Rare Clinical Case Report. Indian J Gynecol Oncolog 22, 22 (2024). https://doi.org/10.1007/s40944-023-00776-8

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  • DOI: https://doi.org/10.1007/s40944-023-00776-8

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