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Optimisation of Cytoreductive Surgery in Relation to Ca 125 in Epithelial Ovarian Cancer

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Indian Journal of Gynecologic Oncology Aims and scope Submit manuscript

Abstract

Background

The ovarian cancer patients have good survival benefit with optimal primary cytoreduction. Preoperative evaluation with imaging and tumour markers for the possibility of optimisation has been routinely practiced. Imaging though provides good insight about operability; the mesenteric, bowel and peritoneal surface diseases are not detected by imaging. The present study evaluates the role of Ca 125 in detecting optimisation in primary cytoreduction.

Materials and Methods

Prospective observational study of 194 patients of stage III epithelial ovarian cancer, with nonmucinous histology, was analyzed for the Ca 125 level in relation to optimisation.

Results

The statistical analysis of study results showed the p value of correlation between Ca 125 values, and residual disease was 0.7 which was statistically not significant.

Conclusion

The results of the present study conclude that the serum Ca 125 levels do not correlate with the optimisation in cytoreduction.

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Authors and Affiliations

  1. Department of Gynaecological Oncology, Kidwai Memorial Institute of Oncology, Bangalore, PIN-560029, India

    K. Shobha & U. D. Bafna

  2. Kidwai Memorial Institute of Oncology, Bangalore, India

    Natarajan Jayashree

  3. MCh Gynaecological Oncology, Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, PIN-110029, India

    Natarajan Jayashree

Authors
  1. K. Shobha
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  2. Natarajan Jayashree
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  3. U. D. Bafna
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Corresponding author

Correspondence to Natarajan Jayashree.

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The authors declare that they have no conflicts of interest.

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Shobha, K., Jayashree, N. & Bafna, U.D. Optimisation of Cytoreductive Surgery in Relation to Ca 125 in Epithelial Ovarian Cancer. Indian J Gynecol Oncolog 16, 13 (2018). https://doi.org/10.1007/s40944-018-0181-1

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  • DOI: https://doi.org/10.1007/s40944-018-0181-1

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