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Adjust antimicrobial agent regimens in older patients to correct for changes in pharmacokinetics and to avoid adverse events

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Abstract

Treating infections with antimicrobial agents in older patients can be challenging. Physiological changes associated with aging can alter the pharmacokinetics of antimicrobial agents; dose adjustments may be required to provide effective and safe treatment. Additionally, the choice of antimicrobial agent can be limited by comorbidities and the use of other medications in these patients. It is vital to tailor the choice of antimicrobial agent and the dose to the clinical profile of the patient.

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    Simon Fung

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Correspondence to Simon Fung.

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Adis author S. Fung is a salaried employee of Adis International Ltd/Springer Nature and declares no relevant conflicts of interest. All authors contributed to this article and are responsible for its content.

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Fung, S. Adjust antimicrobial agent regimens in older patients to correct for changes in pharmacokinetics and to avoid adverse events. Drugs Ther Perspect 40, 145–150 (2024). https://doi.org/10.1007/s40267-024-01065-w

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