Skip to main content
SpringerLink
Log in

A Smartphone-assisted Paper-based Analytical Device for Fluorescence Assay of Hg2+

  • Published:
Chemical Research in Chinese Universities Aims and scope

Abstract

Rapid, efficiency and portable detection systems in low-resource settings with limited laboratory equipment and technical expertise are urgently needed. Herein, an integrated platform composed of a paper-based analytical device and a smartphone detection system for Hg2+ onsite testing was developed. Nitrogen-doped carbon dots(N-CDs) were synthesized by a simple hydrothermal method using citric acid as the carbon source and ethanediamine as the nitrogen source, which gave out bright blue fluorescence under the excitation at 350 nm UV light and the absolute fluorescence quantum yield was 17.1%. The fluorescence of the prepared N-CDs can be effectively quenched by Hg2+. In addition, an external attachment of smartphone for illumination and external light interference was designed to trace the fluorescence signals, and a software application of Android system with simple operation program was developed to perform snapshot and image processing. The smartphone-assisted detection system was combined with the N-CDs decorated paper chip to achieve the sensitive detection of Hg2+ in water samples. This integrated method for reliable sensing of Hg2+ shows a good linear detection range of 10–800 µmol/L(R2=0.9595) with detection limit of 1.07×10−8 mol/L.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Shahvar A., Saraji M., Shamsaei D., Sens. Actuators B Chem., 2018, 5, 891

    Article  Google Scholar 

  2. Yang K., Peretz-Soroka H., Liu Y., Lin F., Lab Chip, 2016, 16, 943

    Article  CAS  Google Scholar 

  3. Zhang D., Liu Q., Biosens. Bioelectron., 2016, 75, 273

    Article  CAS  Google Scholar 

  4. Sumriddetchkajorn S., Chaitavon K., Intaravanne Y., Sens. Actuators B Chem., 2014, 191, 561

    Article  CAS  Google Scholar 

  5. Chen Y., Fu Q., Li D., Xie J., Ke D., Song Q., Tang Y., Wang H., Anal. Bioanal. Chem., 2017, 409, 6567

    Article  CAS  Google Scholar 

  6. Liu Z., Zhang Y., Xu S., Zhang H., Tan Y., Ma C., Song R., Jiang L., Yi C., Anal. Chim. Acta, 2017, 966, 81

    Article  CAS  Google Scholar 

  7. Gong M., Sinton D., Chem. Rev., 2017, 117, 8447

    Article  CAS  Google Scholar 

  8. Liu C., Gomez F. A., Miao Y., Cui P., Lee W., Talanta, 2019, 194, 171

    Article  CAS  Google Scholar 

  9. Fang M., Zhou L., Zhang H., Liu L., Gong Z., Food Chem., 2019, 274, 156

    Article  CAS  Google Scholar 

  10. Xu Y., Liu J., Zhang J., Zong X., Jia X., Li D., Wang E., Nanoscale, 2015, 7, 9421

    Article  Google Scholar 

  11. Qu H., Zhang Y., Qu B., Kong H., Qin G., Liu S., Cheng J., Wang Q., Zhao Y., Biosens. Bioelectron., 2016, 81, 358

    Article  CAS  Google Scholar 

  12. Di Nardo F., Anfossi L., Giovannoli C., Goftman V., Goryacheva I. Y., Baggiani C., Talanta, 2016, 150, 463

    Article  CAS  Google Scholar 

  13. You M., Lin M., Gong Y., Wang S., Li A., Ji L., Zhao H., Ling K., Wen T., Huang Y., Gao D., Q Ma., Wang T., Ma A., Li X., Xu F., ACS Nano, 2017, 6, 6261

    Article  Google Scholar 

  14. Mohammad J. M., Talanta, 2019, 196, 456

    Article  Google Scholar 

  15. Asadian E., Ghalkhani M., Shahrokhian S., Sens. Actuators B Chem., 2019, 293, 183

    Article  CAS  Google Scholar 

  16. Li L., Yu B., You T., Biosens. Bioelectron., 2015, 74, 263

    Article  Google Scholar 

  17. Luo L., Wang P., Wang Y., Wang F., Sens. Actuators B: Chem., 2018, 273, 1640

    Article  CAS  Google Scholar 

  18. Yan F., Kong D., Luo Y., Ye Q., Wang Y., Chen L., Mater. Sci. Eng. C Mater. Biol. Appl., 2016, 68, 732

    Article  CAS  Google Scholar 

  19. Kaur N., Sharma V., Tiwari P., Actuators B: Chem., 2019, 291, 275

    Article  CAS  Google Scholar 

  20. Zhu S., Zhao X., Song Y., Lu S., Yang B., Nano Today, 2016, 11, 128

    Article  CAS  Google Scholar 

  21. Zhou N., Zhang X., Shi Y., Li Z., Feng Z., New J. Chem., 2018, 42, 14332

    Article  CAS  Google Scholar 

  22. Lan M., Zhang J., Chui Y., Wang H., Yang Q., Zhu X., Wei H., Liu W., Ge J., Wang P., Chen X., Lee C., Zhang W., J. Mater. Chem. B, 2015, 3, 127

    Article  CAS  Google Scholar 

  23. Chen T., Wang X., Liu Y., Li B., Cheng Z., Wang Z., Lai W., Liu X., Phys. Chem. Chem. Phys., 2017, 19, 5504

    Article  CAS  Google Scholar 

  24. Hallaj R., Hosseonchi Z., Babamiri B., Zandi S., Spectrochim. Acta, Part A, 2019, 216, 418

    Article  CAS  Google Scholar 

  25. Zhang R., Chen W., Biosens. Bioelectron., 2014, 55, 83

    Article  CAS  Google Scholar 

  26. Huang H., Weng Y., Zheng L., Yao B., Weng W., Lin X., J. Colloid. Interf. Sci., 2017, 506, 373

    Article  CAS  Google Scholar 

  27. Li M., Wang B., An X., Li Z., Zhu H., Mao B., Calatayud D., James T., Dyes and Pigments, 2019, 170, 107476

    Article  CAS  Google Scholar 

  28. Qiu Y., Dong L., Xiang D., Li L., Zhu L., Chem. Res. Chinese Universities, 2018, 34(6), 971

    Article  CAS  Google Scholar 

  29. Tanvir F., Yaqub A., Tanvir S., An R., Anderson W., Materials, 2019, 12, 1533

    Article  Google Scholar 

  30. Qi Y., Zhao J., Weng G., Li J., Li X, Zhu J., Zhao J., J. Mater. Chem. C, 2018, 6, 12283

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. State Key Laboratory of Supramolecular Structure and Materials, Institute of Theoretical Chemistry, Jilin University, Changchun, 130012, P. R. China

    Jiawen Ye, Yijia Geng, Fanghao Cao, Dan Sun, Shuping Xu & Weiqing Xu

  2. School of Chemistry and Environmental Engineering, Changchun University of Science and Technology, Changchun, 130022, P. R. China

    Jiawen Ye & Jingjing Chang

  3. School of Chemical Engineering and New Energy Materials, Zhuhai College, Jilin University, Zhuhai, 519041, P. R. China

    Jiawen Ye, Fanghao Cao & Qidan Chen

Authors
  1. Jiawen Ye
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yijia Geng
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Fanghao Cao
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Dan Sun
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Shuping Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jingjing Chang
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Weiqing Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Qidan Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Weiqing Xu or Qidan Chen.

Additional information

Supported by the National Natural Science Foundation of China(Nos.21873039, 21573087, 21573092), the Basic and Applied Basic Research Foundation of Guangdong Province, China(No.2019A1515010596), the “Three Levels” of Talent Project of Zhuhai College, Jilin University, China(No.2018TL006) and the Science and Technology Innovation Team Project of Zhuhai College, Jilin University, China(No. 2018CXKYTD005).

Electronic Supplementary Information

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ye, J., Geng, Y., Cao, F. et al. A Smartphone-assisted Paper-based Analytical Device for Fluorescence Assay of Hg2+. Chem. Res. Chin. Univ. 35, 972–977 (2019). https://doi.org/10.1007/s40242-019-9234-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40242-019-9234-y

Keywords

Search

Navigation