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Tuning the Corrosion Resistance, Antibacterial Activity, and Cytocompatibility by Constructing Grooves on the Surface of Ti6Al4V3Cu Alloy

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Acta Metallurgica Sinica (English Letters) Aims and scope

Abstract

Ti6Al4V3Cu alloy is a promising biomaterial for combating implant-related infection. However, the antibacterial property of Ti6Al4V3Cu is expected to be enhanced due to the low content of Cu element in titanium. To address this issue, the antibacterial property of Ti6Al4V3Cu was tailored by the grooves with different groove widths (30 μm, 60 μm, and 90 μm) that were constructed on the surface of the Ti6Al4V3Cu by selective laser melting. The effect of grooves on corrosion resistance, antibacterial property, and cytocompatibility was investigated. The electrochemical tests showed that the corrosion resistance decreased with increasing groove width. The antibacterial tests indicated that the groove with a width of 30 μm and 90 μm groups showed better antibacterial activity against S. aureus (> 90%) compared with the groove with a width of 60 μm. The in vitro study suggested that all samples with different grooves were found to exhibit good cytocompatibility with osteoblast cells. It is considered that creating grooves on Ti6Al4V3Cu by selective laser melting is a promising strategy to enhance the antibacterial activity without sacrificing cytocompatibility.

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Acknowledgements

The design of the study and collection, analysis, and interpretation of data were supported by the National Natural Science Foundation of China (No. 51801198), the Funds of Scientific and Technological Plan of Fujian Province (Nos. 2020Y9064, 2020Y0083 and 2020L3026) and Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China (No. 2021ZZ111).

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Authors and Affiliations

  1. Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China

    Minghui Zhou, Yanming Gan, Cheng Ji, Yan Chen, Yanjin Lu & Jinxin Lin

  2. College of Chemistry, Fuzhou University, Fuzhou, 350108, China

    Minghui Zhou & Yanming Gan

  3. Liaoning Provincial Key Laboratory of Oral Diseases, School and Hospital of Stomatology, China Medical University, Shenyang, 110002, China

    Hui Sun & Qiang Wang

  4. Fujian College, University of Chinese Academy of Sciences, Fuzhou, 350002, China

    Yanjin Lu & Jinxin Lin

  5. Fujian Science and Technology Innovation Laboratory for Optoelectronic Information of China, Fuzhou, 350108, China

    Yanjin Lu & Jinxin Lin

  6. College of Chemistry and Materials Science, Fujian Normal University, Fuzhou, 350007, China

    Yanjin Lu & Jinxin Lin

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  1. Minghui Zhou
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Correspondence to Jinxin Lin or Qiang Wang.

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Zhou, M., Sun, H., Gan, Y. et al. Tuning the Corrosion Resistance, Antibacterial Activity, and Cytocompatibility by Constructing Grooves on the Surface of Ti6Al4V3Cu Alloy. Acta Metall. Sin. (Engl. Lett.) 36, 1979–1998 (2023). https://doi.org/10.1007/s40195-023-01620-w

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  • DOI: https://doi.org/10.1007/s40195-023-01620-w

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