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HIV and HPV as Fatal Partners

  • Uterine Fibroids (I Meinhold-Heerlein, Section Editor)
  • Published:
Current Obstetrics and Gynecology Reports Aims and scope Submit manuscript

Abstract

Human papillomavirus (HPV) infection is the commonest sexually transmitted infection globally. Many other types of sexually transmitted infections have been considered as co-factors for HPV infection, ranging from Neisseria gonorrhoeae to Chlamydia trachomatis to herpes simplex 2, to name a few. HPV infection, persistent infection with high-risk types, infection with multiple types as well as cervical cancer and its precursors are known to be more prevalent in human immunodeficiency virus (HIV)-infected women. Whether HPV infection stimulates transmission of HIV is still controversial but if this is true, HPV vaccination to prevent HPV infection, particularly with types 16 and 18, may have a significant public health impact. HPV vaccination has been shown to be highly effective in preventing disease caused by its target types, e.g. 16/18 (bivalent vaccine) and 16/18/6/11 (quadrivalent) and appear to be as safe and immunogenic in HIV-infected and HIV-uninfected individuals.

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Compliance with Ethics Guidelines

Conflict of Interest

Lynette Denny declares personal fees from Merck, GlaxosmithKline, and Roche for appearances on speaker’s forums.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. University of Cape Town/Groote Schuur Hospital, H45, Old Main Building, Observatory, 7925, Cape Town, South Africa

    Lynette Denny

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  1. Lynette Denny
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Correspondence to Lynette Denny.

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This article is part of the Topical Collection on Uterine Fibroids

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Denny, L. HIV and HPV as Fatal Partners. Curr Obstet Gynecol Rep 4, 143–148 (2015). https://doi.org/10.1007/s13669-015-0122-2

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  • DOI: https://doi.org/10.1007/s13669-015-0122-2

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