Skip to main content
SpringerLink
Log in

Study on the Sensitivity Indicators by Sandstorm PM10 Exposure

  • Original article
  • Published:
Toxicology and Environmental Health Sciences Aims and scope Submit manuscript

Abstract

Objective

PM10 is one of the typical pollutants involved with sandstorm. More and more attentions on the sensitive bio-marks by PM10 exposure are attracted. This study is to probe the sensitivities indicators’ levels by sandstorm PM10 exposure.

Methods

A cross-sectional study involving administration on a survey 150 residents in Erlianhaote was performed. PM10 concentrations collected on a daily basis from the local monitor stations from March to June, 2016 were employed as the daily environmental exposure levels (DEEL). Indicators of IGM, CRP, CC16, IL16, IGA, LGG, IGE and IL8 were assayed, as well as questionnaire for individual disease histories were done.

Results

Results indicated that PM10 exposure level was positively related to IGG, IGM, IGA, LGG and CRP, age was positively related to CRP and LGG, and history of cardiovascular disease was related to CRP by multi-factor line regression analysis. Further analysis revealed that levels of IGG (p<0.01) and IGM (p<0.05) increased in the group with PM10 DEEL exceeded 200 μg/m3, compared to the group with the average exposure levels less than 200 μg/m3; while levels of IGM (p<0.05), IGA (p<0.05), LGG (p<0.05) and CRP (p<0.01) were found higher in the group with PM10 DEEL exceed 300 μg/m3, compare to the group with the levels less than 300 μg/m3.

Conclusion

Our findings suggest that sandstorm PM10 exposure might contribute to the changes of some immune and inflammation index. These findings provide clinical indicators for the sandstorm PM10 exposure and help to understand the risk of sandstorm pollution.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Chen, F. et al. Does temperature modify the effect of PM10 on mortality? A systematic review and metaanalysis. Environ. Pollut. 224, 326–335 (2017).

    Article  CAS  PubMed  Google Scholar 

  2. Sajani, S. Z., Hänninen, O., Marchesi, S. & Lauriola, P. Comparison of different exposure settings in a case—crossover study on air pollution and daily mortality: counterintuitive results. J. Expo. Sci. Environ. Epidemiol. 21, 385–394 (2011).

    Article  Google Scholar 

  3. Zanobetti, A. & Schwartz, J. The Effect of Particulate Air Pollution on Emergency Admissions for Myocardial Infarction: A Multicity Case-Crossover Analysis. Environ. Health Perspect. 113, 978–982 (2005).

    Article  PubMed  PubMed Central  Google Scholar 

  4. Downs, S. H. et al. Reduced Exposure to PM10 and Attenuated Age-Related Decline in Lung Function. N. Engl. J. Med. 357, 2338–2347 (2007).

    Article  CAS  PubMed  Google Scholar 

  5. Yuan, Z. in Effects of air pollutants on the inflammatory cytokines in rats (Jilin university, China, 2008).

    Google Scholar 

  6. Yang, C., Renqun, W., Su, Z. & Chunling, X. Effect of mixed air pollutants on the levels of interferon-γ and CC16 in bronchoalveolar lavage fluid of rats. J. China Med. Univ. 36, 436–437 (2007).

    Google Scholar 

  7. Miao, J. & Sang, N. PM_(10) Exposure Induces Myocardial Injuries in Rats. J. Shanxi Univ. 37, 648–652 (2014).

    Google Scholar 

  8. Sakamoto, N. et al. Effect of atorvastatin on PM10-induced cytokine production by human alveolar macrophages and bronchial epithelial cells. Int. J. Toxicol. 28, 17–23 (2009).

    Article  CAS  PubMed  Google Scholar 

  9. Nguyen, T. T. et al. A Longitudinal Study of Association between Heavy Metals and Itchy Eyes, Coughing in Chronic Cough Patients: Related with Non-Immunoglobulin E Mediated Mechanism. Int. J. Environ. Res. Public Health 13, doi: 10.3390/ijerph13010110 (2016).

  10. Lihua, G. et al. Effect of PM10 on human immunological parameters. J. Zhengzhou Univ. Med. Edition 43, 546–548 (2008).

    Google Scholar 

  11. Li, X. Y., Gilmour, P. S., Donaldson, K. & Macnee, W. Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro. Thorax 51, 1216–1222 (1996).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Liu, X. C. et al. Analysis of mass concentration of atmospheric particulate matter in a sandstorm course and its affecting factors in the Taklimakan Desert. Sci. Cold Arid Region 4, 259–264 (2012).

    Article  CAS  Google Scholar 

  13. Zhang, F. et al. Ambient air quality and the effects of air pollutants on otolaryngology in Beijing. Environ. Monit. Assess. 187, doi:10.1007/s10661-015-4711-3 (2015).

  14. Wong, C. M. et al. Cancer Mortality Risks from Longterm Exposure to Ambient Fine Particle. Cancer Epidemiol. Biomarkers Prev. 25, 839–845 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Chen, B. & Kan, H. Air pollution and population health: a global challenge. Environ. Health Prev. Med. 13, 94–101 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Zeka, A., Zanobetti, A. & Schwartz, J. Short term effects of particulate matter on cause specific mortality: effects of lags and modification by city characteristics. Occup. Environ. Med. 62, 718–725 (2005).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Golomb, E. et al. Myocardial mitochondrial injury induced by pulmonary exposure to particulate matter in rats. Toxicol. Pathol. 40, 779–788 (2012).

    Article  CAS  PubMed  Google Scholar 

  18. Dong, S. et al. Ambient Particulate Pollutants and C Reactive Protein Variability in Elderly Residents in Beijing. J. Environ. Health. 28, 1035–1039 (2011).

    CAS  Google Scholar 

  19. Liang, L., Yates, A. P., Mather, E. & Pickersgill, M. in Society for Endocrinology Meeting. 414–416.

  20. Thompson, D., Pepys, M. B. & Wood, S. P. The physiological structure of human C-reactive protein and its complex with phosphocholine. Structure 7, 169–177 (1999).

    Article  CAS  PubMed  Google Scholar 

  21. Shao, Y. & Dong, C. H. A review on East Asian dust storm climate, modelling and monitoring. Glob. Planet. Change 52, 1–22 (2006).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Chaoyang District, Beijing, 100012, PR China

    Hongmei Wang

  2. State Environmental Protection Key Laboratory of Regional Eco-process and Function Assessment, Chinese Research Academy of Environmental Sciences, Chaoyang District, Beijing, 100012, PR China

    Shihai Lv

  3. China University of Mining & Technology (Beijing), Beijing, 100083, PR China

    Baolu Wang & Caihong Yu

Authors
  1. Shihai Lv
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hongmei Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Baolu Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Caihong Yu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hongmei Wang.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lv, S., Wang, H., Wang, B. et al. Study on the Sensitivity Indicators by Sandstorm PM10 Exposure. Toxicol. Environ. Health Sci. 10, 65–71 (2018). https://doi.org/10.1007/s13530-018-0348-2

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13530-018-0348-2

Keywords

Search

Navigation