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Aptasensor for environmental monitoring

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Abstract

Aptamers are single-stranded oligonucleotides (DNA or RNA) capable of folding into well-defined structures and motifs that allow them bind to various target molecules with high specificity and affinity. The crucial ability of aptamers is interaction with a given target from small ions to molecular level that makes them useful in many applications for specific detection of various analytes. Nowadays aptamer is an effective tool not only for in vitro research in diagnostic methods, drug delivery and treatment therapy, but also for the development of nucleic-acid-based sensors in industrial waste management, pollution control and environmental toxicology. This mini review is focused on discussion and updating about the global researches in nucleic-acid-based sensors for environmental issues.

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  1. These authors contributed equally to this work

Authors and Affiliations

  1. School of Biological Sciences, Chungbuk National University, 1 Chungdae-Ro, Seowon-Gu, Cheongju, 28644, Republic of Korea

    Phat-Loc Nguyen, Simranjeet Singh Sekhon, Ji-Young Ahn, Sung-Jin Cho & Yang-Hoon Kim

  2. College of Veterinary Medicine, Western University of Health Sciences, 309 E Second Street, Pomona, CA, 91766, USA

    Jung Ho Ko & Lyon Lee

  3. Department of Bioprocess Engineering, Chonbuk National University, 567 Baekje-daero, Deokjin-Gu Jeonju, 54896, Republic of Korea

    Jiho Min

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  1. Phat-Loc Nguyen
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Correspondence to Jiho Min or Yang-Hoon Kim.

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Nguyen, PL., Sekhon, S.S., Ahn, JY. et al. Aptasensor for environmental monitoring. Toxicol. Environ. Health Sci. 9, 89–101 (2017). https://doi.org/10.1007/s13530-017-0308-2

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