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Management of postoperative chylous ascites after surgery for ovarian cancer: a single-institution experience

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Abstract

Postoperative chylous ascites is a rare complication from operative trauma to the cisterna chyli or lymphatic vessels in the retroperitoneum. In the present study, we aimed to identify the incidence of postoperative chylous ascites in patients treated for ovarian cancer and to describe its management. We retrospectively reviewed all patients submitted to surgery for ovarian cancer at our Institution from October 2016 to November 2018. We analyzed the clinicopathological features, including the primary tumor histology, stage, grade, surgical procedure, median number of harvested pelvic and para-aortic lymph nodes. We described our experience in the diagnosis and management of chylous ascites. Five hundred and forty-six patients were submitted to surgery for ovarian cancer and 298 patients received pelvic and/or para-aortic lymphadenectomy. Chylous ascites occurred in 8 patients with an incidence of 1.4% in the overall population and a 2.68% among patients receiving lymphadenectomy. All patients received total parenteral nutrition (TPN) with Olimel N4E 2000 mL (Baxter®) and somatostatin therapy with 0.2 mL per 3 times/day for a median of 9 days (range 7–11). Median hospital stay was 15 days (range 7–16). All patients were successfully managed conservatively and none required surgical correction. Conservative management of chylous ascites with TPN, somatostatin and paracentisis is feasible and effective. These data should be confirmed by prospective multicentric studies.

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Authors and Affiliations

  1. Division of Gynecologic Oncology, Department of Women’s and Children’s Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

    Giuseppe Scaletta, Lorena Quagliozzi, Stefano Cianci, Virginia Vargiu, Giovanni Scambia & Anna Fagotti

  2. Department of Gastroenterology, Metabolic-endocrine and Nefro-urologic Science, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

    Maria Cristina Mele

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  1. Giuseppe Scaletta
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  2. Lorena Quagliozzi
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  3. Stefano Cianci
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  4. Virginia Vargiu
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  5. Maria Cristina Mele
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  6. Giovanni Scambia
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Correspondence to Stefano Cianci.

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Scaletta, G., Quagliozzi, L., Cianci, S. et al. Management of postoperative chylous ascites after surgery for ovarian cancer: a single-institution experience. Updates Surg 71, 729–734 (2019). https://doi.org/10.1007/s13304-019-00656-x

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