Skip to main content
Log in

Segmentation and Volumetric Analysis of Heart from Cardiac CT Images

  • Original Article
  • Published:
Cardiovascular Engineering and Technology Aims and scope Submit manuscript

Abstract

Purpose

Cardiac CT is a valuable diagnostic tool in evaluating cardiovascular diseases. Accurate segmentation of the heart and its structures from cardiac CT and MRI images is essential for diagnosing functional abnormalities, treatment plans and cardiovascular diseases management. Accurate segmentation and quantitative assessments are still a challenge. Manual delineation of the heart from the scan images is labour-intensive, time-consuming, and error prone as it depends on the radiologist's experience. Thus, automated techniques are highly desirable as they can significantly improve the efficiency and accuracy of image analysis.

Method

This work addresses the above problems. A new, image-driven, fast, and fully automatic segmentation method was developed to segment the heart from CT images using a processing pipeline of adaptive median filter, multi-level thresholding, active contours, mathematical morphology, and the knowledge of human anatomy to delineate the regions of interest.

Results

The algorithm proposed is simple to implement and validate and requires no human intervention. The method is tested on the 'Image CHD' DICOM images (multi-centre, clinically approved single-phase de-identified images), and the results obtained were validated against the ground truths provided with the dataset. The results show an average Dice score, Jaccard score, and Hausdorff distance of 0.866, 0.776, and 33.29 mm, respectively, for the segmentation of the heart's chambers, aorta, and blood vessels. The results and the ground truths were compared using Bland-Altmon plots.

Conclusion

The heart was correctly segmented from the CT images using the proposed method. Further this segmentation technique can be used to develop AI based solutions for segmentation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

Data Availability

This work did not use any primary data (images) during the research. All the images were considered from the published work (cited).

References

  1. Kalus, S. Coronary artery CT (normal) | Radiology Case | Radiopaedia.org. Radiopaedia. https://radiopaedia.org/cases/coronary-artery-ct-normal

  2. WHO. Cardiovascular Diseases. World Health Organization, 2022. https://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1

  3. Selver, M., et al. Analysis on the use of multi-sequence MRI series for segmentation of abdominal organs. J. Phys.: Conf. Ser. 574:012139, 2015. https://doi.org/10.1088/1742-6596/574/1/012139.

    Article  Google Scholar 

  4. Habijan, M., D. Babin, I. Galić, H. Leventić, K. Romić, L. Velicki, and A. Pižurica. Overview of the whole heart and heart chamber segmentation methods. Cardiovasc. Eng. Technol. 11(6):725–747, 2020.

    Article  PubMed  Google Scholar 

  5. Automatic whole heart segmentation based on image registration. https://www.researchgate.net/publication/295706446_Automatic_whole_heart_segmentation_based_on_image_registra.

  6. Adaloglou, N. Introduction to medical image processing with Python: CT Lung and vessel segmentation without labels. AI Summer, https://theaisummer.com/medical-image-python/.

  7. Lin, A., M. Kolossváry, M. Motwani, et al. Artificial intelligence in cardiovascular CT: current status and future implications. J. Cardiovasc. Comput. Tomogr. 15(6):462–469, 2021.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Campadelli, P., Casiraghi, E., Lombardi, G. Automatic liver segmentation from abdominal CT scans. 14th International Conference on Image Analysis and Processing (ICIAP 2007), 2007. https://doi.org/10.1109/iciap.2007.4362863.

  9. Nasr-Esfahani, M., Mohrekesh, M., Akbari, M., Soroushmehr, S. M., Nasr-Esfahani, E., Karimi, N., et al. Left ventricle segmentation in cardiac MR images using fully convolutional network. 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018.

  10. X. Xu et al., "ImageCHD: A 3D computed tomography image dataset for classification of congenital heart disease," in Medical Image Computing and Computer Assisted Intervention – MICCAI 2020., 2020, vol. 12264, 77–87

  11. Larrey-Ruiz, J., J. Morales-Sánchez, M. C. Bastida-Jumilla, et al. Automatic image-based segmentation of the heart from CT scans. J. Image Video Proc. 2014:52, 2014. https://doi.org/10.1186/1687-5281-2014-52.

    Article  Google Scholar 

  12. Rim, B., S. Lee, A. Lee, H. W. Gil, and M. Hong. Semantic cardiac segmentation in chest CT images using K-means clustering and the mathematical morphology method. Sensors (Basel). 21(8):2675, 2021. https://doi.org/10.3390/s21082675.PMID:33920219;PMCID:PMC8070040.

    Article  PubMed  Google Scholar 

  13. Image processing for engineering and Science. Coursera. https://www.coursera.org/specializations/image-processing.

  14. Mongan, J., L. Moy, and C. E. Kahn. Checklist for artificial intelligence in medical imaging (claim): a guide for authors and reviewers. Radiol.: Artif. Intell. 2020. https://doi.org/10.1148/ryai.2020200029.

    Article  PubMed  Google Scholar 

  15. van Timmeren, J. E., D. Cester, S. Tanadini-Lang, H. Alkadhi, and B. Baessler. Radiomics in medical imaging-"how-to" guide and critical reflection. Insights Imaging. 11(1):91, 2020. https://doi.org/10.1186/s13244-020-00887-2.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Vallières, M., A. Zwanenburg, B. Badic, C. Cheze Le Rest, D. Visvikis, and M. Hatt. Responsible radiomics research for faster clinical translation. J. Nucl. Med. 59(2):189–193, 2018. https://doi.org/10.2967/jnumed.117.200501.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Wiggins, W. F., K. Magudia, T. M. S. Schmidt, S. D. O’Connor, C. D. Carr, M. D. Kohli, and K. P. Andriole. Imaging AI in practice: a demonstration of future workflow using integration standards. Radiol. Artif. Intell. 3(6):e210152, 2021. https://doi.org/10.1148/ryai.2021210152.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Menon, B. K., et al. Multiphase CT angiography: a new tool for the imaging triage of patients with acute ischemic stroke. Radiology. 275(2):510–520, 2015. https://doi.org/10.1148/radiol.15142256.

    Article  PubMed  Google Scholar 

  19. Huang, W., Y. Xu, D. Lu, Y. Shi, and G. Lu. Single-versus multi-phase acquisition protocol for prospective-triggered sequential dual-source CT coronary angiography: comparison of image quality and radiation dose. Clin. Imaging. 39(4):597–602, 2015. https://doi.org/10.1016/j.clinimag.2015.02.014.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

We would like to acknowledge Mr. Yogeesh M, the project manager at SIEMENS Healthcare, Germany for his valuable guidance to realize this requirement from the technical perspective (code reviews and suggestions for code optimization).

Funding

The authors declare that no funds, grants, or other support were received during the preparation of this manuscript

Author information

Authors and Affiliations

Authors

Contributions

R: Methodology, Writing original draft, Work design, Coding, results interpretation, getting feedback from the doctor. KNM: Conceptualization, Checking the data authenticity and its diagnostic quality, Investigation, Methodology, Visualization, Validation, Writing original draft. AK: Conceptualization, Data curation, Formal analysis, Project administration, Supervision, Validation, Checking the data authenticity and its diagnostic quality. VK: Investigation, Formal analysis, Computing resources, Code review, Review and editing.

Corresponding author

Correspondence to K. N. Manjunath.

Ethics declarations

Competing interest

The authors have no relevant financial or non-financial interests to disclose

Disclosure of Potential Conflict of Interest

The authors have no conflict of interest in this work

Research Involving Human Participants and Animals

This study did not involve any human participants either directly or indirectly

Informed Consent

Not applicable

Additional information

Associate Editor Derek J. Dosdall, Ph.D. oversaw the review of this article.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rashmitha, Manjunath, K.N., Kulkarni, A. et al. Segmentation and Volumetric Analysis of Heart from Cardiac CT Images. Cardiovasc Eng Tech (2024). https://doi.org/10.1007/s13239-024-00715-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s13239-024-00715-4

Keywords

Navigation