Abstract
Introduction
Non-healing wound causes significant morbidity and mortality of patients. One of the rare causes behind non-healing wound infection is M. tuberculosis which often remains undiagnosed.
Aim
The aim of this study was to determine the tuberculosis as one of the causes of non-healing wound.
Methods
Wounds that did not heal even after secondary suturing and tissue biopsies were sent for histopathological examination. The cases diagnosed with tuberculosis received anti-tubercular treatment. Follow-up was done after 7 and 14 days of treatment, and response was seen in terms of reduction in inflammation and discharge.
Results
Of the 36 patients, five patients had tubercular infection out of which one patient revealed tubercular granuloma, two revealed epitheloid cells, Langhans cells, whereas two revealed non-specific chronic inflammation in histopathology.
Conclusion
A high degree of suspicion and tissue biopsy is required in case of delayed or non-healing wounds to diagnose tuberculosis as a cause. Even if typical tubercular granuloma is not visible in histopathology, the presence of epitheloid cells, giant cells, Langhans cells or predominant lymphocytic infiltrate equally suggests tubercular tissue infection.
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We certify that we have no affiliation with or involvement in any organisation or entity with any financial interest (such as honoraria, educational grants, participation in speakers) or non-financial interest (such as personal or professional relationship, affiliation, knowledge) in the subject matter or material discussed.
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All procedures followed were in accordance with ethical standard of responsible committee on human experimentation (institutional and national) and with Helsinki Declaration of 1975, as revised in 2008. Informed consent was obtained from all patients for being included in the study.
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Dr Amrita Chaurasia is a Professor in Department of Obs and Gynae, MLN Medical College, Prayagraj, India. Dr Vandana Ojha is an Assistant Professor in Department of Obs and Gynae, MLN Medical College, Prayagraj, India. Dr Osheen Bonal is a Junior Resident in Department of Obs and Gynae, MLN Medical College, Prayagraj, India. Dr Yashi Srivastava is a Junior Resident in Department of Obs and Gynae, MLN Medical College, Prayagraj, India.
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Chaurasia, A., Ojha, V., Bonal, O. et al. Non-healing Wounds: A Delayed Wound Infection by Mycobacterium Tuberculosis. J Obstet Gynecol India 70, 225–229 (2020). https://doi.org/10.1007/s13224-020-01320-w
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DOI: https://doi.org/10.1007/s13224-020-01320-w