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Green Synthesis, Characterization, and Antifungal Activity of Synthesized Silver Nanoparticles (AgNPS) from Garcinia Kola Pulp Extract

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Abstract

The prevention or cure of microbial infections are mostly combated with the use of antibiotics. However, the activity of most of the available antibiotics had been nullified by fungi resistance. This study was aimed at the investigation of the antifungal property of silver nanoparticles (AgNPs) synthesized from Garcinia kola pulp. The pulp of Garcinia kola were obtained from its ripe fruit, dried and pulverized into fine particles and extracted with water. The extract was mixed with 1mM aqueous silver nitrate following necessary procedure to form AgNPs. The AgNPs synthesized were characterized and screened against tested fungi using standard method. The inhibition zones were measured and recorded after incubation of the plates at a temperature of 35 °C for 24 h. The morphological assessment of the synthesized AgNPs confirmed the variation in particle size ranging from 24 to 10 nm with an average size distribution of 17 nm and a spherical shape. The synthesized AgNPs show good activity against tested fungi strains with inhibition zones ranging from 6 to 17 mm which is comparable to the inhibition zones demonstrated by the control in the range of 18 to 24 mm. This study indorsed the use of AgNPs against fungi infections owning to the antifungal activity displayed against tested fungi strains.

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Acknowledgements

The authors acknowledge all the staff of the school of department of pure and applied Chemistry Department for their support.

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The authors did not receive support from any organization for the submitted work.

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China

    Sunday Adewale Akintelu

  2. Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, Nigeria

    Sunday Adewale Akintelu

  3. Department of Agricultural Economics, Ladoke Akintola University of Technology, Ogbomoso, Nigeria

    Seyifunmi Charles Olugbeko

  4. Department of Chemistry, Louisiana State University, Baton Rouge, LA, USA

    Aderonke Similoluwa Folorunso

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  1. Sunday Adewale Akintelu
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  2. Seyifunmi Charles Olugbeko
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  3. Aderonke Similoluwa Folorunso
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Correspondence to Sunday Adewale Akintelu.

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The research does not involve humans and animals, it only involved the use of microorganisms.

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This study was approved and ethical clearance was given by the Research Ethics Committee (ERC) of Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology.

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This study present a comprehensive report on the antifungal investigation of AgNPs synthesized from Garcinia kola pulp extract which revealed its potential antifungal activity profile against selected clinical isolate.

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Akintelu, S.A., Olugbeko, S.C. & Folorunso, A.S. Green Synthesis, Characterization, and Antifungal Activity of Synthesized Silver Nanoparticles (AgNPS) from Garcinia Kola Pulp Extract. BioNanoSci. 12, 105–115 (2022). https://doi.org/10.1007/s12668-021-00925-3

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