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Artifacts in Quantitative analysis of myocardial perfusion SPECT, using Cedars-Sinai QPS Software

  • Technologist Corner
  • Published:
Journal of Nuclear Cardiology Aims and scope

Abstract

Quantitative analysis of myocardial perfusion Single photon emission computerized tomography (SPECT) images is increasingly applied in modern nuclear cardiology practice, assisting in the interpretation of myocardial perfusion images (MPI). There are different extensively validated state-of-the-art software packages, including QPS (cedars-Sinai), Corridor 4DM (University of Michigan) and Emory cardiac toolbox (Emory university), providing highly accurate and reproducible data. However, these software packages may suffer from potential artifacts related to patient or technical factors. By recognizing the source of such artifacts, the interpreting physician can avoid misinterpretation of MPI study. In this review, we discuss some of technical pitfalls that may occur in Quantitative Perfusion SPECT software (QPS, cedars-Sinai Medical center).

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Abbreviations

SPECT:

Single photon emission computerized tomography

MPI:

Myocardial perfusion imaging

LHR:

Lung to heart uptake ratio

TID:

Transient ischemic dilation

LV:

Left ventricle

RV:

Right ventricle

ROI:

Region of interest

LAD:

Left anterior descending coronary artery

LCx:

Left circumflex coronary artery

RCA:

Right coronary artery

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Disclosures

The authors report no conflicts of interest.

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Authors and Affiliations

  1. Department of Nuclear Medicine and Molecular Imaging, Rajaie Cardiovascular, Medical & Research Center, Vali-Asr Ave.Nyayesh Blvd., 1996911151, Tehran, Iran

    Hadi Malek MD & Nahid Yaghoobi MD

  2. Department of Nuclear Medicine, Rasool-e Akram Hospital Iran University of Medical Sciences, Tehran, Iran

    Raheleh Hedayati MD

Authors
  1. Hadi Malek MD
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  2. Nahid Yaghoobi MD
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  3. Raheleh Hedayati MD
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Correspondence to Nahid Yaghoobi MD.

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Malek, H., Yaghoobi, N. & Hedayati, R. Artifacts in Quantitative analysis of myocardial perfusion SPECT, using Cedars-Sinai QPS Software. J. Nucl. Cardiol. 24, 534–542 (2017). https://doi.org/10.1007/s12350-016-0726-6

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  • DOI: https://doi.org/10.1007/s12350-016-0726-6

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