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Surgical treatment for a rare case of duodenal gangliocytic paraganglioma accompanied with lymph node metastasis

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Abstract

We report a rare case of duodenal gangliocytic paraganglioma accompanied with lymph node metastasis. An asymptomatic 58-year-old woman was admitted for the evaluation of abnormal liver enzyme test results. Abdominal computed tomography and upper gastrointestinal endoscopy revealed a 27-mm pedunculated tumor of the papilla of Vater. Adenocarcinoma of the papilla with muscularis propria invasion was suspected; therefore, pancreaticoduodenectomy with lymph node dissection was performed. There were no perioperative complications. A definitive diagnosis of gangliocytic paraganglioma of the papilla of Vater with lymph node metastases was confirmed by pathological examinations, which is a rare condition. The patient was discharged on her 16th postoperative day, and no recurrence or metastases were identified during the 18-month follow-up period. We herein discuss the surgical treatment for this rare case and present a review of related literature.

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Abbreviations

GP:

Gangliocytic paraganglioma

CEA:

Carcinoembryonic antigen

CA19-9:

Carbohydrate antigen 19-9

CT:

Computed tomography

LI:

Labeling index

LNM:

Lymph node metastasis

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Acknowledgements

This work was supported by Grants-in-Aid for Research from the National Center for Global Health and Medicine (30-1021to N.T.).

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Authors and Affiliations

  1. Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan

    Toko Miyazaki, Nobuyuki Takemura, Fuminori Mihara, Kyoji Ito & Norihiro Kokudo

  2. Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan

    Hideki Miyazaki & Toru Igari

Authors
  1. Toko Miyazaki
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  2. Nobuyuki Takemura
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  3. Fuminori Mihara
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  4. Kyoji Ito
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  5. Hideki Miyazaki
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  7. Norihiro Kokudo
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Correspondence to Nobuyuki Takemura.

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Miyazaki, T., Takemura, N., Mihara, F. et al. Surgical treatment for a rare case of duodenal gangliocytic paraganglioma accompanied with lymph node metastasis. Clin J Gastroenterol 15, 712–716 (2022). https://doi.org/10.1007/s12328-022-01636-2

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  • DOI: https://doi.org/10.1007/s12328-022-01636-2

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