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Congenital Cutaneous Candidiasis: Uncommon Entity or Underdiagnosed?

  • Fungal Infections of Skin and Subcutaneous Tissue (A Bonifaz and M Pereira, Section Editors)
  • Published:
Current Fungal Infection Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

We have created a general review of the disease in this article, especially of the clinical features, diagnosis, new treatments and preventive measures.

Summary

Congenital cutaneous candidiasis is a vertically transmitted fungal infection which affects term and premature newborn. It is considered as an underdiagnosed pathology, and infection caused by Candida albicans is considered the most common aetiology.

Recent Findings

Clinically characterized by erythematous papular lesions and pustules with collarette scale. It can also affect other organs and systems by causing an invasive fungal infection. Diagnosis is clinical, and the agent can be isolated; other tools of diagnosis include direct examination and skin biopsy. Regarding the treatment, this infection can be self-limiting in a majority of cases and topical antifungals constitute the treatment of choice. However, in the case of a systemic condition, the first-line treatment is amphotericin B. Prognosis is good, although it is unfavourable in the case of a systemic condition.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Author information

Authors and Affiliations

  1. Dermatology Service, Federico Gómez Children’s Hospital of Mexico, Mexico City, Mexico

    A. P. Sánchez-Padilla, A. M. Valencia-Herrera, M. E. Toledo-Bahena, C. A. Mena-Cedillos & M. Duarte-Abdala

  2. Research Department, Federico Gómez Children’s Hospital of Mexico, Mexico City, Mexico

    M. Salazar-García

  3. Mycology Department, Dermatology Service, Eduardo Liceaga General Hospital of Mexico, Mexico City, Mexico

    Alexandro Bonifaz

Authors
  1. A. P. Sánchez-Padilla
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  2. A. M. Valencia-Herrera
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  3. M. E. Toledo-Bahena
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  4. C. A. Mena-Cedillos
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  5. M. Duarte-Abdala
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  6. M. Salazar-García
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  7. Alexandro Bonifaz
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by SPAP and TBME. The first draft of the manuscript was written by SPAP and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to M. E. Toledo-Bahena.

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Conflict of Interest

Alicia Sanchez-Padilla, Adriana Valencia-Herrera, Mirna Toledo-Bahena, Carlos Mena-Cedillos, Mario Duarte-Abdala, Marcela Salazar-Garcia and Alexandro Bonifaz declare no conflicts of interest relevant to this manuscript.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Fungal Infections of Skin and Subcutaneous Tissue

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Sánchez-Padilla, A.P., Valencia-Herrera, A.M., Toledo-Bahena, M.E. et al. Congenital Cutaneous Candidiasis: Uncommon Entity or Underdiagnosed?. Curr Fungal Infect Rep 13, 175–180 (2019). https://doi.org/10.1007/s12281-019-00359-1

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  • DOI: https://doi.org/10.1007/s12281-019-00359-1

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