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Does applying resolution recovery to normal databases confer an advantage over conventional 3D-stereotactic surface projection techniques?

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Abstract

We evaluated a novel normal database (NDB) generated using single photon emission computed tomography (SPECT) data obtained from healthy brains by using a SPECT/CT system, analyzed using a resolution recovery (RR) technique applied to the three-dimensional stereotactic surface projection (3D-SSP) technique. We used a three-dimensional ordered subset expectation maximization method (3D-OSEM) with applied scatter correction (SC), attenuation correction, and RR to reconstruct the data. We verified the accuracy of the novel NDB’s values (Z, extent, and error scores), and compared the novel NDB to the 3D-SSP technique by using simulated misery perfusion-related patient data from a conventional NDB. In addition, Z, extent, and error scores at the precuneus, cuneus, and posterior cingulate were compared under different reconstruction conditions by using the patient data. In the simulation, Z scores decreased when using the novel NDB corrected using computed tomography-based attenuation correction (CTAC), SC, and RR. The extent scores of the posterior cingulate increased using the novel NDB, relative to the other NDBs. The error score with the novel NDB without RR decreased by 15% compared to that of the conventional NDB. Z scores generated from patient data decreased in the novel NDB with RR. The extent scores tended to decrease in the novel NDB with RR. The extent scores in the novel NDB with RR improved at the posterior cingulate, compared to the scores with the other NDBs. However, applying RR to the novel NDB conferred no advantage because the cut-off of the current Z score must be reconsidered when using the additive RR technique.

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Acknowledgements

This study was supported by the Digital Image Scientific Research Meeting (Mihara, Hiroshima, Japan).

Author information

Authors and Affiliations

  1. Biological Systems Sciences Program, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Shoubara, Japan

    Nobuhiro Yada & Hideo Onishi

  2. Department of Radiology, Shimane University Hospital, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan

    Nobuhiro Yada, Masahiro Miyai, Kentarou Ozasa, Masuo Haramoto & Yasushi Yamamoto

  3. Department of Radiology, Faculty of Medicine, Shimane University, Izumo, Japan

    Takashi Katsube & Hajime Kitagaki

  4. Department of Neurology, Faculty of Medicine, Shimane University, Izumo, Japan

    Keiichi Onoda & Shuhei Yamaguchi

Authors
  1. Nobuhiro Yada
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  2. Hideo Onishi
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  3. Masahiro Miyai
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  4. Kentarou Ozasa
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  5. Takashi Katsube
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  6. Keiichi Onoda
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  7. Masuo Haramoto
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  8. Yasushi Yamamoto
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  9. Shuhei Yamaguchi
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  10. Hajime Kitagaki
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Corresponding author

Correspondence to Nobuhiro Yada.

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Conflicts of interest

This study investigated brain perfusion images in a collaborative research program with Nihon Medi-Physics Co., Ltd, which provided 123I-IMP.

Funding

Authors Shuhei Yamaguchi and Hajime Kitagaki received research grants from Nihon Medi-Physics Co., Ltd (Grant Number: B1D25007). The other authors received no specific Grant form from either public or commercial funding agencies.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Statement of Human Rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Yada, N., Onishi, H., Miyai, M. et al. Does applying resolution recovery to normal databases confer an advantage over conventional 3D-stereotactic surface projection techniques?. Radiol Phys Technol 10, 240–248 (2017). https://doi.org/10.1007/s12194-017-0391-8

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  • DOI: https://doi.org/10.1007/s12194-017-0391-8

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