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Simultaneous Determination of Foramsulfuron and Orthosulfamuron in Four Common Grains Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry

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Abstract

Foramsulfuron and orthosulfamuron are two important sulfonylurea herbicides and have been widely used for the weed control in grain field. But their residues and toxicities have also caused many problems. In this study, the QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) method and UPLC-MS/MS (ultra-performance liquid chromatography coupled with tandem mass spectrometry) were combined to simultaneously determine them in soybeans, wheat, rice, and maize. The suitable extractants (acetonitrile for soybeans and wheat while acetonitrile containing 1% formic acid for rice and maize) and sorbents (octadecylsilane (C18) for soybeans and wheat while primary secondary amine (PSA) for rice and maize) were tested and selected. In this study, the determinations of the target compounds were achieved in < 5.0 min and the limits of quantification were 0.005 mg kg−1 in the four grain matrices. The method showed excellent linearity (R2 > 0.9990) for the target compounds. And the recovery studies of foramsulfuron and orthosulfamuron performed in the four matrices at three spiked levels (5, 10, and 100 μg L−1) showed good average recoveries (75.16~106.45%) and reproducibility (inter-day relative standard deviations (n = 15) ranged from 4.08 to 15.95%). This method will be useful for the quick and simultaneous detection of foramsulfuron and orthosulfamuron residues in soybeans, wheat, rice, and maize.

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Funding

This work was supported by the National Key Research and Development Program of China (2017YFD0800700) and the National Natural Science Foundation of China (31371970).

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Authors and Affiliations

  1. State Key Laboratory for Biology of Plant Disease and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China

    Chang Ma, Xingang Liu, Xiaohu Wu, Fengshou Dong, Jun Xu & Yongquan Zheng

  2. Scientific Observing and Experimental Station of Crop Pests in Guilin, Ministry of Agriculture, Guilin, 541399, China

    Xingang Liu

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  1. Chang Ma
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  2. Xingang Liu
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  3. Xiaohu Wu
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  4. Fengshou Dong
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  5. Jun Xu
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Correspondence to Xingang Liu.

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Chang Ma declares that she has no conflict of interest. Xingang Liu declares that he has no conflict of interest. Xiaohu Wu declares that he has no conflict of interest. Fengshou Dong declares that he has no conflict of interest. Jun Xu declares that she has no conflict of interest. Yongquan Zheng declares that he has no conflict of interest.

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All authors named in a manuscript are entitled to the authorship and have approved the final version of the submitted manuscript. This article does not contain any studies with human or animal subjects.

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Ma, C., Liu, X., Wu, X. et al. Simultaneous Determination of Foramsulfuron and Orthosulfamuron in Four Common Grains Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry. Food Anal. Methods 11, 1789–1796 (2018). https://doi.org/10.1007/s12161-018-1155-8

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  • DOI: https://doi.org/10.1007/s12161-018-1155-8

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