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A Molecularly Imprinted Polymer for the Selective Extraction and Determination of Fenvalerate from Food Samples Using High-Performance Liquid Chromatography

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Abstract

A molecularly imprinted polymer (MIP) for the selective solid-phase extraction (SPE) was prepared using fenvalerate (FEN) as template and pyrrole as monomer. For comparison, non-imprinted polymer (NIP) was synthesized in the absence of FEN. A molecularly imprinted solid-phase extraction (MISPE) procedures were performed in column method by florescence detection technique. High-performance liquid chromatography (HPLC) analysis using a C18 column (300 mm × 3.9 mm, 5 μm), acetonitrile/water (1:1 v/v) as the mobile phase at a flow rate of 1.5 mL min−1 was applied for the quantitative determination. The parameters that affect the efficiency of method were thoroughly investigated. The measurements were done under the optimal conditions. The influence of desorption solvent, amount of sorbent, pH, and ionic strength were investigated. The limit of detection (LOD) and limit of quantification (LOQ) of method were obtained as 0.19 and 0.63 ng g−1, respectively. The relative standard deviation of standard solution (RSD%) was obtained 4.07 %. The application of method to separation and preconcentration of FEN in food samples were examined. The minimum and maximum recovery (%) through the spiking 50 ng of FEN per gram of samples was obtained as 85.30 and 96.50, respectively.

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Conflict of Interest

Azizollah Nezhadali declares that he has no conflict of interest. Javad Feizy declares that he has no conflict of interest. Hamed Reza Beheshti declares that he has no conflict of interest. This article does not contain any studies with human or animal subjects.

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Authors and Affiliations

  1. Department of Chemistry, Payame Noor University, Mashhad, Iran

    Azizollah Nezhadali & Javad Feizy

  2. Department of Chemistry, Payame Noor University, P.B. 19395-4697, Tehran, 19569, Iran

    Azizollah Nezhadali

  3. Testa Quality Control Laboratory, Mashhad, Iran

    Javad Feizy & Hamed Reza Beheshti

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  1. Azizollah Nezhadali
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  2. Javad Feizy
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  3. Hamed Reza Beheshti
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Correspondence to Azizollah Nezhadali.

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Highlights

Chemical PPy-MIP for FEN analysis was synthesized.

The MIP was successfully used in MISPE method.

MIP has been applied for the determination of FEN in food samples.

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Nezhadali, A., Feizy, J. & Beheshti, H.R. A Molecularly Imprinted Polymer for the Selective Extraction and Determination of Fenvalerate from Food Samples Using High-Performance Liquid Chromatography. Food Anal. Methods 8, 1225–1237 (2015). https://doi.org/10.1007/s12161-014-0004-7

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